Jon Chu

Doctor & Dentist in Training. Ultra (3) and Marathon (17) runner, Cook - interested in Surgery, Kinesiology, Fitness & Prev Med. All views my own.

[David Sinclair @davidasinclair]

Muscles are an endocrine organ. When you move, they release molecules (myokines) that protect your brain, heart & immune system

[Jon Chu @Chudaism_]

So great to see friends and colleagues, old and new, at @BAOMSOfficial this week - Fantastic learning and always a pleasure to be reminded why we do what we do!

[Peter Brennan @BrennanSurgeon]

Just had large study of >2000 UK medical students accepted for publication

>50% of respondents felt the allocation system for newly qualified (FY) doctor posts was unfair

46% noticed negative impact on physical/mental health

Up to 48% are considering career outside the NHS

[Jon Chu @Chudaism_]

Currently reading this whilst sleep deprived pre/post night shift haha

[Nicholas Fabiano, MD @NTFabiano]

Why do living organisms need sleep?

A new theory suggests that myelin acts as a proton capacitor, accumulating energy during sleep.

🧵1/12

[Rory McIlroy @McIlroyRory]

Dreams do come true.

[Jon Chu @Chudaism_]

i love the internet

[djcows @djcows]

the market crash looks so much nicer in ghibli

[∩ @zachpogrob]

'4000 weeks' is by far the most insane framing for how short life is.

[David Sinclair @davidasinclair]

A key to success is to spend your 20s & 30s reading voraciously:
1. History & biographies
2. How to write well
3. Finance & Economics
4. Personal development
5. Relationships

[Dr. Rhonda Patrick @foundmyfitness]

Metastasis—the spread of cancer to new organs—is responsible for 90% of all human cancer deaths.

Exercise—particularly high-intensity exercise—increases blood flow and shear stress in blood vessels. This mechanical force makes it harder for circulating tumor cells to survive, spread, and form metastases.

Several lines of evidence support this anti-cancer mechanism:

- In vitro studies show that exercise-equivalent levels of shear stress kill up to 90% of circulating tumor cells, including highly metastatic and drug-resistant breast cancer cells.

- In animal studies, mice who exercise have fewer circulating tumor cells and a 50–60% lower rate of metastasis and tumor growth.

- In humans, higher physical activity levels are linked to reduced cancer recurrence, possibly due to lower metastatic spread.

The powerful force of blood flow achieved during exercise actively disrupts cancer spread, which is just one of the ways exercise benefits the long-term health and survival of cancer patients.

[FoundMyFitness Clips @fmfclips]

Physical inactivity is as deadly as smoking

Yet, we don’t treat it that way

By age 50, most Americans have lost 10% of their peak muscle mass—by 70, up to 40%

This isn’t about vanity; it’s about survival

Resistance training isn’t optional; it’s the most powerful defense against aging we have

[Jon Chu @Chudaism_]

Feeling extremely attacked for the size of the meals I inhale hahahaha

[David Sinclair @davidasinclair]

Recipe to feel great each day:
•Don’t finish big meals
•Avoid sugary foods
•Stretch at every chance
•Walk whenever possible
•Get a standing desk
•Optimize sleep
•Be kind

[Dr. Rhonda Patrick @foundmyfitness]

Combining omega-3s, vitamin D, and regular exercise may reduce biological aging far beyond the impacts of these interventions in isolation, a new study indicates.

Specifically, supplementing with omega-3s alone reduced biological age on several next-generation epigenetic clocks during the 3-year study. It also slowed the pace of biological aging.

Omega-3s combined with vitamin D or exercise had an even greater benefit on phenotypic age when compared to any singe intervention. The biggest benefit for phenotypic age—a nearly 4-month reduction—was observed when omega-3s, vitamin D, and exercise were combined.

This aligns with what we know about the individual effects of these interventions. Having a low omega-3 index is more strongly associated with all-cause mortality than smoking. Vitamin D plays a critical role in modulating several mechanisms associated with the "hallmarks of aging." Being sedentary is one of the strongest predictors of an early death—and exercise is one of the most powerful ways to delay it.

These results suggest that while omega-3s have powerful anti-aging effects, they also enhance the benefits of supplementing with vitamin D and engaging in regular exercise. There is a synergy among healthy lifestyle habits.

Study PMID: 39900648

[David Sinclair @davidasinclair]

Omega-3 plus vitamin D “slows biological aging by 3-4 months over 3 years, particularly when combined with exercise.” 👏

[Jon Chu @Chudaism_]

currently reading this in between uni tutorials post-night shifts haha

[Bryan Johnson @bryan_johnson]

go to bed
right now
it can wait until tomorrow
yes you do need more than 6 hr
you are not fine
you do have a lot going on
and why you need sleep
I know your friend only sleeps 4 hrs
he also frequently melts down
off you go

[Years Progress @YearsProgress]

2025 is 1% complete.

[Simon Fleming 🛠 @OrthopodReg]

The requested 🇦🇺 pay update:

*Currently* working as a (year 1) ortho surgeon boss in QLD (salary varies by state & “metro centre” vs DGH)

I take home £7,250 - £10,500 per month (on-call dependant)

work 4 days a week, no private, 1:7 on-call

Main issue is a shortage of anaesthetists

It is also sometimes quite warm

#medtwitter

[Chris Williamson @ChrisWillx]

“The worst outcome in this world is not having self-esteem. If you don’t love yourself, who will?” — @naval

[Jon Chu @Chudaism_]

🥲

[Jon Chu @Chudaism_]

Interesting topic of discussion not talked about enough I think. How the stress index of your work and rota patterns affect your metabolism and cravings!

[Dr Luke Craddock @DrLukeCraddock]

I can empathise with this hard. Since finals and F1 I’ve gained over 40lbs and am honestly the unfittest I have ever been.

I am hopeful to try and get back into shape after Christmas, if my heavy ED rotation allows it 🤣

[Gurwinder @G_S_Bhogal]

Even the smartest people are dumb most of the time. This is because cognition is computationally costly, so the brain must ration rationality.