The Cold Spring Harbor Asia (CSHA) meeting - Nuclear Architecture and Function is coming up soon! (Sept 1-5, 2025). Abstract submission deadline extended to July 18. Fantastic speakers & beautiful city (Suzhou) with Royal Garden. Check out here: https://t.co/jER6uINI8D
Today in @Nature, we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas.
We built an interactive browser to explore the spatial data: https://t.co/Xy3JcsSpYw
Paper link below👇
Brain cancer leverages the same tools as the developing brain 🧠! In our new study, published today in @Nature, we mapped neocortical development to explore brain cancer and neuropsychiatric risks. #stemcells#brainresearch
https://t.co/8t8WHyQiS4
My first talk at the CSHL Neurodegenerative Diseases Conference 🧠🧬! Grateful to share my work and inspired by the incredible science. Thrilled to reconnect with old friends and meet new ones! Big thanks to my mentor Dr. Piao @LabPiao for her support and the meeting organizers!
Glad to share the peer-reviewed version of the @mgheffel manuscript now in @Nature. In collaboration with @lab_paredes , we studied the chromatin conformation and DNA methylation changes during human hippocampus and frontal cortex development. https://t.co/T8idzapvf5
Happy to share the final version of our #GAGEseq published today @NatureGenet! The single-cell co-assay for #scHiC and #scRNA reveals 3D genome & gene expression interplay in mouse cortex (also integration w/ #MERFISH) and during human hematopoiesis. 1/3 https://t.co/y6wGcTBslO
The big reveal. My post-doc Jiuling Yang will be giving an oral presentation on her exciting findings on the immune checkpoint protein PVRL2 (aka Nectin2, CD112) at the AACR on Monday: https://t.co/YYqTv7rznk @UCSF, @UCSFstemcell, @UCSFUrology, @UCSFCancer
Preterm birth affects 1 in 10 infants, with few treatment options. But a UCSF-led study shows how precision medicine in pregnancy could change that. “This study calls for a precision framework for future drug development,” senior author Jingjing Li says. https://t.co/rW0ZP4PAwu
New work from @jingjingSF@wang156658 + team reveals who can benefit from preterm birth therapy, calling for a precision-medicine approach that could identify targets for novel treatments. To conduct the study, researchers developed a machine-learning framework. More via @UCSF
A Multiomics, Spatiotemporal, and Single Cell Atlas for Mapping Cell-Type-Specific Dysregulation at the Maternal-Fetal Interface https://t.co/ULWXOTL8Pz #biorxiv_genomic
Integrative #MachineLearning analysis reveals genes associated with preterm labor + identifies potential drug targets. The work not only contributes to addressing preterm labor but also establishes a valuable method for studying other complex diseases. Congrats @jingjingSF + team
We are delighted that our PRIME method found its home @MolecularCell. The cover art is exquisitely designed by the leader behind the PRIME development @Xingjie_Ren. Congratulations to @Xingjie_Ren@HanYang_Henry and the entire team! https://t.co/XMwAxQWAhY
What's the link between #genome organization & transcriptional control? While most TADs are stable, @TomSexton_lab &co show (by ectopic induction in ESCs) that #transcription can directly remodel #TADs, with a context-dependent sensitivity #PLOSBiology https://t.co/WVSLJZpaQJ
We're thrilled to announce the selected candidates for this year's Mount Sinai Neuroscience Seminars! Join us in welcoming exceptional postdocs to share their insights in #neuroscience. SAVE THE DATES for this enlightening series.
@SinaiBrain#MSNseminars
@Bingjie_Zhang_ I have been following your work since your presentation at the 2021 SC Genomics Days. Your research is truly inspiring to me and has had a great influence on my work. Feeling happy for your achievements :)