Updates from the WHO Classification of Breast Tumors, 6th Edition (not published yet)
Invasive lobular carcinoma with extracellular mucin
- Recently described
- Needs to be separated from classic ILC and mucinous carcinoma in view of more aggressive biological behavior and less favorable prognosis
Dr. Tan #USCAP #pathology #PathX #PathTwitter
Ectopic pregnancy with fetal parts and yolk sac remnant (or simply yolk sac), Pic 1
It is not common to see a yolk sac in a POC specimen or even in ectopic pregnancy. It looks concerning, but once you see one, you'll recognize it faster next time.
Yolk sac, high power (Pic 2)
For the best educational thread on yolk sac, check @leon_metlay's post: https://t.co/wNu2SXpYqe
Another yolk sac post from Dr. Kaur's ISGYP presentation: https://t.co/x8H67pzXBZ
#everydayGYN #PathX #pathtwitter
Case of Invasive Carcinoma with Apocrine Differentiation 🌸🔬
Invasive carcinoma with apocrine differentiation is a rare tumor with characteristic apocrine morphology and harbors frequent mutations in the PI3K3CA/AKT/mTOR pathway.
#PathX#PathTwitter#breastpath
Stunning contrast between flat urothelial carcinoma in situ (right side of each image) and reactive urothelium (left side)
CIS➡️enlarged, irregular, & hyperchromatic nuclei
Reactive➡️small, uniform nuclei w/vesicular chromatin + intraepithelial acute & chronic inflammation