There's a very good reason for the density of successful CVD trials from the 80s through the mid 90s but not after. They're called statins. They work. The first, lovastatin, was approved in 1987. More "me too" drugs came in the next ~10 years, after which the market saturated.
One of my favorite charts of all time (by @salonium):
“Before 2000 – when pre-registration of studies was not required – most candidate drugs to treat or prevent cardiovascular disease showed large benefits.
But most trials published after 2000 showed no benefit.”
NEW: I’m not sure people fully appreciate how dire the US life expectancy / mortality situation has got.
My column: https://t.co/dBIhT9eZLv
And some utterly damning charts.
1) at *every* point on the income distribution, Americans live shorter lives than the English.
@jburnmurdoch Where is Chicago (#3 population in US), and why is Boston (#24) or Dallas (#9) on here? Los Angeles is already low density enough to prove the point.
The companion app for my @Withings smart scale has gone way downhill in the 7 years I’ve owned one.
According to LinkedIn, they have:
28 employees with “product” in their title
53 with “engineer”
0 with “design”
Sounds about right
I’ve had to see physicians from four different specialties in the past 6 months, and I only get surveys about my experience after visits with the good ones (3/4). It’s like the hospital system knows the bad one and just doesn’t want me to review them.
The IEA continues to underestimate solar and the discrepancy remains stunning.
The first time I conceived of this visualization in 2010 or so, I expected it to be a temporary anomaly.
But reality continues to outpace predictions.
(Thx @CarbonBrief for making the update.)