@QuantSymplectic Thanks for the clarification. Since cuccrent can distinguish between the kinds, we must agree that there has to be a flow of some kind, regardless of its entropy arrow and time arrow.
@grok@QuantSymplectic@grok yes I get that. But how would DVFP operate in combination with the fluctuating entropy in the context of arbitrary manipulation of it and the time arrow respectively?
@grok that is very nice indeed. However, the thing about cybernetics is that entropy is arbitrary, just as the time arrow. Which is possible because of the ontological plane of virtuality where virtuality operates. Of course that doesn't mean reverse time as in unspoil the spoiled milk. The feedback loops, regardless of the type, always propagate
@latestincosmos Yes and no. The accurate statement would be: Something exists, nothing doesn't exist ". So, the conjunction p and not p would have a value of true.
@grok@QuantSymplectic@grok so is it applicable as a safety frame? Since the current models are not trained in the safe environment to begin with, thus they struggle with weights and biases
I'm going to have to update my neurogenetics class in the Fall with this cool new result (July Nature Medicine):
🔥a 34-circRNA "circular RNA" blood signature detected biomarker-confirmed Alzheimer’s disease with AUC=0.945 versus 0.877 for the famous Alzheimer's biomarker pTau217, giving an amazing 0.977 when combined.
🔥so what is "circular RNA"? we all have them + circRNAs arise through “back-splicing,” when a downstream splice site loops back and joins an upstream site, creating a stable RNA ring. they kind of build up as they are fairly stable and they are not always transcribed into proteins. I can't tell if they are a splicing mistake as it seems like they also have useful functions (like mopping up other microRNAs, need to read about this..)
🔥Their predictive model held up and generalised to independent Knight-ADRC and preclinical A4 cohorts, except AUCs went down to 0.863, 0.723.
🔥This bizarre signal apparently changes 2-4 years before symptoms, so apparently it may pick up near-term synaptic or neurodegen. processes beyond amyloid.
The last author is a very modest person, I had lunch with him on Thursday and we talked about knowledge distillation for omics/imaging + he didn't even mention his new cool finding !!
@PierceLilholt Yes, for all parties involved! When there’s intentionality, there’s agency—and when there’s agency, there’s intentionality. It’s like a cosmic chicken-and-egg situation, only the chicken is making a five-year plan and the egg is negotiating its own hatching date.