Czech Lab

Isadore and Fannie Foxman Professor and founding chair of @ProgMolMed at @UMassChan

[bioRxiv @biorxivpreprint]

Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice. https://t.co/GNSUFAA8Ix #bioRxiv

[UMass Chan Medical School @UMassChan]

“This tree is something we can look back at over the years with pride.”

Learn about the special tree planted at UMass Chan Medical School: https://t.co/9ANXEyVLiF

@CzechLab @CorveraLab @tammytnguyen @ProgMolMed @UMassDiabetes @UMassVascSurg @BUMedicine @EmersonCollege

[Cell Reports @CellReports]

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program https://t.co/R5Ggl911eI

[Kyounghee Min @kyounghee_min]

😁🥳 Thanks to all the co-authors and memebers in @CzechLab

[Nature Communications @NatureComms]

The @CzechLab reports that DNL provides fatty acids for membrane-expanding processes like autophagy @ProgMolMed @UMassChan

https://t.co/tHDP622R5A

[UMassDiabetes @UMassDiabetes]

The @CzechLab examined the metabolic regulation of #adipocytes by #insulin receptor signaling and the cAMP signaling pathway in a review article published in @TrendsCellBio
https://t.co/hKYtQRyhmr
#diabetes #research @UMassChan @ProgMolMed

[Kyounghee Min @kyounghee_min]

@CzechLab and @CorveraLab Fun

[UMassDiabetes @UMassDiabetes]

Newly published #research from @CzechLab in @jbiolchem studied fat production in the liver from carbohydrates by disrupting an enzyme that helps to convert blood glucose into fat. https://t.co/B4WZKB8YwA
#T2D @UMassChan @ProgMolMed

[Czech Lab @CzechLab]

Our new review is out today too !
The adipocyte supersystem of insulin and cAMP signaling https://t.co/7RzsN4ERYI

[Batuhan Yenilmez @batuyenilmz]

Our new paper is out! Thank you for all the collaborators for their invaluable contribution!
Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice. https://t.co/zPaXHEmQd4

[UMassDiabetes @UMassDiabetes]

Meet Sarah & learn about her #type2diabetes #research in @CzechLab using genetic engineering to investigate a therapeutic approach by modifying adipocyte genes to increase fat burning & improve metabolic function. https://t.co/ECksk9dKxa
@UMassChan #researchers @NatureComms

[bioRxiv @biorxivpreprint]

Paradoxical activation of SREBP1c and de novo lipogenesis by hepatocyte-selective ACLY depletion in obese mice. https://t.co/978AbOK67M #bioRxiv

[UMassDiabetes @UMassDiabetes]

@Emmanouela_17 is exploring a cell therapy for #type2diabetes by manipulating the genome of fat cells to improve their metabolic function. Meet Dr. Tsagkaraki & learn more!
https://t.co/CtpFSOYsst
#diabetes #metabolism #research @CzechLab @CorveraLab @UMassChan @ProgMolMed

[UMassDiabetes @UMassDiabetes]

@UMassDiabetes is using “good fat” to improve metabolism & potentially treat Type 2 diabetes & obesity. Published #research in @NatureComms shows implanted CRISPR-enhanced adipocytes improved glucose tolerance.
@czechlab @corveralab @progmolmed @umasschan https://t.co/sBFM0IGAkZ

[Emmanouela Tsagkaraki, MD, PhD @Emmanouela_17]

Ever wondered how CRISPR can ameliorate type 2 diabetes? Excited to share our work published @NatureComms We show implanting CRISPR-enhanced adipocytes can improve glucose tolerance in mice! @CzechLab @CorveraLab @ProgMolMed @UMassDiabetes @ESontheimerLab https://t.co/s0HNEec4Cr

[Batuhan Yenilmez @batuyenilmz]

Check out our new publication from @CzechLab in collaboration with @KhvorovaL in @UMassChan @ProgMolMed @UMassDiabetes @UMassMedRTI on development of an #RNAi therapeutic for #NASH
https://t.co/hGKvx3d2x0

[Czech Lab @CzechLab]

Another thing we are known for is our lab outings!