Dahlia Perez

Biologist, PhD in regenerative research. Interested in hearts, pooches and beaches.

[Eldad Tzahor @Tzahore]

🎉💖🥳Thrilled to share our new study: “Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischaemic injury”, headed by Avraham Shakked @AbingtonSA. 🥳💖🎉

Link to paper --> https://t.co/v3UGm0W5ix 1/12

[Dahlia Perez @dahliaeperez]

Fun in the sun during the Keystone Conference #KSheartfail thank you to the organizers for the great talks and great times!!! @benoitbruneau @MansoorHusaini

[Dahlia Perez @dahliaeperez]

huge congratulations to my labmate @AharonovAlla on the release of her work! ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration
https://t.co/9YZQyNtRkz

[Shoval Miyara @MiyaraShoval]

EXTREMELY excited to share the beautiful and elegant work of my labmate @AharonovAlla DECODING THE ERBB2 DERIVED CARDIAC REGENERATION! @Tzahor_Lab @Tzahore ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration https://t.co/J7L5Aoc7Ws

[Eldad Tzahor @Tzahore]

@AharonovAlla @abingtonSA @jmartinlab We show a potent ERBB2-driven regeneration of scarred hearts (a model of heart failure in mice) and that this utilises core-EMT processes

[Eldad Tzahor @Tzahore]

@AharonovAlla @abingtonSA @jmartinlab YAP is activated and required downstream of ERBB2 signaling in cardiomyocytes and its activity is mechanically driven by cytoskeleton and nuclear envelope remodeling (aka, mechanotransduction pathway)

[Eldad Tzahor @Tzahore]

@AharonovAlla @abingtonSA @jmartinlab We also shaw that YAP gets phosphorylated on S274 and S352 (non-Hippo sites) and this is essential for cardiomyocyte division

[Eldad Tzahor @Tzahore]

@AharonovAlla @abingtonSA @jmartinlab In sum, we demonstrate a potent ERBB2-mediated YAP mechanosensory signaling involving EMT-like characteristics that drive heart regeneration in adult mice. END

[Natalia Davidzohn @NDavidzohn]

Very excited to share my recent work! Now in @JExpMed. https://t.co/DgMfnWr3us
Thanks to all the team members @AdiBiram @Eilema

[Dahlia Perez @dahliaeperez]

Huge congratulations to my labmates for publishing the next chain in the agrin story of cardiac regeneration!

[Shoval Miyara @MiyaraShoval]

Our lab @Tzahor_Lab @Tzahore and collaborators now show that a single dose of Agrin after myocardial infarction limits adverse remodeling of the heart and improves cardiac repair in PIGS- taking this possible treatment one step forward towards the clinic!!https://t.co/xGOvvRHzVP

[Shoval Miyara @MiyaraShoval]

The beautiful work of the talented @OrenYifa is now out! Make sure you read that elegant study ASAP! The small molecule Chicago Sky Blue promotes heart repair following myocardial infarction in mice @Tzahor_Lab @Tzahore @oncidium21 @genzelinakh https://t.co/cfyjwmLC7b

[Dahlia Perez @dahliaeperez]

Congrats Oren!

[Oren Inzelberg Yifa @OrenYifa]

Happy to share our paper about the small molecule CSB that attenuates inflammation and improves contractility to promote heart repair @JCI_insight !!!
https://t.co/fUSaOJGEAI

@Tzahore @Tzahor_Lab @BursacLab
#WeizmannScience #HeartRepair #heartdisease #Cardiology