Have you ever wondered what animal superpowers can teach us about our own DNA? Join us in Cambridge, MA (or online) for a Broad Discovery Series talk on Wednesday, May 20 at 6 pm ET with @eenork of @darwinsarkfnd. Register: https://t.co/pQfSkgg4Pn
Anthropic just published best practices for Opus 4.7 with Claude Code. The biggest changes:
Default effort is now "xhigh" (new level between high and max).
Fixed thinking budgets are gone. The model decides when to think deeply on its own.
Updated: Ask a frontier genomic foundation model (Evo2) about your DNA variant !
AskEvo2 : https://t.co/F5USYlYn3F
Get Evo 2 DNA variant log-likelihoods in your browser - no Docker, no GPU, no API keys, no login.
Paste ref and alt sequences : get wild-type + mutant log-likelihoods. Single variant and batch modes available.
Validated against ClinVar: BRCA1 AUC=0.90, MLH1 AUC=0.95, n=200 each. Results are raw Evo2 model outputs (no supervised linear probing or retraining applied).
Runs via a Modal backend, hosted on Hugging Face Spaces.
@goodfire_ai@arcinstitute@pdhsu@garykbrixi@NVIDIAHealth
@camsoft2000 Exactly, and if you express these thoughts, there will be a ton of people commenting on your lack of skills files , under using the plan mode and blah blah
@tangming2005@anshulkundaje@genbioai What do you think of the goodfire findings ? It could help decrypt non coding variants , or find similar regulatory regions .