Danny Evans

PhD Candidate (Computational Molecular Biophysics) @JHU | All views are my own.

[Danny Evans @danielJEvans]

Now on to my next adventure: finding a postdoc lab! If you have an opening and think I might be a good fit, please do not hesitate to contact me!

[Danny Evans @danielJEvans]

1/3 Just released my latest preprint! Introducing EVADE - a Python package designed for analyzing pocket volumes and dihedral correlations. Using EVADE, I uncovered statistical pitfalls and novel insights into the enigmatic protein 3CLPro. https://t.co/N02wmC1zf4

[Danny Evans @danielJEvans]

3/3 Here's the Github link to EVADE: https://t.co/8DEuYR0NLq

[Danny Evans @danielJEvans]

@adele_valeria I think evaluating whether a place is "better"/"worse" is a hard problem. A simple number ranking would struggle to capture the full range of factors. Saying "scores low on this particular scale" seems more accurate than "worst".

[Danny Evans @danielJEvans]

@elisew00 Thanks a lot!

[Danny Evans @danielJEvans]

In 2020 I got a CNC machine for woodcarving. I recently discovered how to carve protein structures. It’s fun when an unrelated interest intersects with my work! (I chose ubiquitin as a test case b/c it’s small and well-known. The carving process should work for most proteins.)

[Program in Molecular Biophysics at Johns Hopkins @JHU_Mol_Biophys]

The Program in Molecular Biophysics @JohnsHopkins is finally on Twitter! Follow us for news about our terrific graduate students and faculty. You can find out about our Ph.D. program at https://t.co/FwvsJszR6O . Please follow and RT!

[Remy Yovanno @rem_yo]

New preprint from the Lau Lab and @Lab_FURUKAWA. We used molecular dynamics simulations and electrophysiology (@TsungHan_Chou) to study the role of D-serine binding to NMDAR LBDs.

[Remy Yovanno @rem_yo]

So excited to share our lab’s newest paper with @Lab_FURUKAWA, including some of my thesis work using MD simulations and network modeling to study Fab binding to the NMDAR. Thankful to have worked with such an amazing team!

[Stephen Fried JHU @fried_lab]

@fried_lab's first foray in structural bioinformatics is out on @github. Great work by new grad student, @ManriquezEdgar. DomainMapper annotates protein domain structure, and properly labels non-contiguous, insertional, and circularly permuted domains. https://t.co/4tQv8YGpnS

[Danny Evans @danielJEvans]

(Actually Albert Lau is my PI, not a co-worker... but including all that in a single well-structured tweet seemed difficult. Thus I wrote a simpler tweet, and added this long clarifying footnote. David Foster Wallace might approve!)

[Danny Evans @danielJEvans]

The TACTICS paper is published in JCIM! Thanks to @SanimRahman4 @rem_yo @morgbeck @0xAfif (and David Cao, Milan Patel, and Albert Lau, whose twitters I don't know) for being great co-workers!

[Sanim Rahman @SanimRahman4]

Pleased to share the exciting work led by @danielJEvans on identifying druggable pockets from molecular dynamics simulations is now published in JCIM!

https://t.co/jEG1NDYwCr

[Danny Evans @danielJEvans]

@KennyMarincin Congratulations; that's awesome!

[Danny Evans @danielJEvans]

@CWolberger @SanimRahman4 @remy_yo Thanks a lot!

[Danny Evans @danielJEvans]

#BPS2021 is now underway... I'm excited to hear about the latest work from @rem_yo, shown in a Thursday 11:15-11:30 talk "Role of D-Serine Binding To The NMDA Receptor Ligand-Binding Domain". Having seen some of the data, I can assure you it's worth attending!

[Danny Evans @danielJEvans]

We developed ML-based software for finding cryptic sites. We applied the method to 3 proteins: two from SARS-CoV-2, and one from yersinia pestis. Thanks to everyone who contributed to the project! The preprint is available at https://t.co/EXaYDARGaQ