HydraDAO

Funding and incubating replacement research to extend human lifespan. • $HYDRA 🫀

[HydraDAO @daohydra]

This December, everything changes.

Introducing HydraDAO:

[Kai Micah Mills @kaimicahmills]

early bird tickets are now live for the space biostasis summit 2027 🥶

what happens when you put hundreds of the top space and biostasis experts in a room together?

this event will birth entire industries

on the agenda is space medicine, cryobiology, hibernation & torpor, national security, and much more

space center houston, feb 9-11
https://t.co/h1oGzvK2Tq

[Andy Yee @ahkyee]

Head transplant is one of the groundbreaking approaches to cognitive immortality. Now, @daohydra is backing critical research into spinal-cord fusion, the technology needed to make it possible.

$HYDRA

[HydraDAO @daohydra]

Happy to see Hydra's spinal fusion work mentioned in @techreview!

"The team cut through the spinal cords of three pigs at a point midway along their backs and then tested whether the severed nerve bodies could be fused back together using a surgical sealant. According to that paper, which appeared in the journal PLOS One, all the pigs regained the ability to stand and even walk unsteadily."

Soon... @theseusbio

[Antonio Regalado @antonioregalado]

The "Impossible Issue" of MIT Technology Review is out.

I wrote about six far-out ideas for preserving a person's mind.

https://t.co/ztpL7e2ydg

[Kai Micah Mills @kaimicahmills]

officially announcing the next @cryodao research project:

$259,000 for "TOTAL RECALL" 🧊🧠

setting out to prove that complex mammalian memory can survive cryopreservation with legendary cryobiologist greg fahy and principal investigator regina monaco

two complementary approaches will be pursued: testing whether learned responses survive cryopreservation in neural cultures and/or hippocampal slices, and whether the molecular changes associated with training are preserved

together, these approaches target one of the central questions for cryopreservation: can the information underlying memory survive?

[Karl Pfleger @KarlPfleger]

Crazy, unexpected science news today: the brain is actually 2 colocated but independent organs that develop from 2 totally separate progenitor cells in early development. Big implications for some research areas (eg ALS) & for creating ethical brainless clones for transplant.

[HydraDAO @daohydra]

👀🤫

[Eli Mohamad @elimohamad]

@theseusbio rising soon
breaking your spinal cord should not be the end

[Kai Micah Mills @kaimicahmills]

on february 9-11, 2027…

space meets biostasis @spacebiostasis

announcing the official date for the upcoming space biostasis summit, hosted at space center houston in texas

we’re bringing together the top space agencies, scientists, cryobiologists, funders, and astronauts to discuss:

- human metabolic depression for space exploration
- the latest breakthroughs and recent progress in cryobiology
- space search and rescue and medical evacuation

we will kick off the coalition that will develop the biostasis technologies required to make humanity multiplanetary

(and even share our latest groundbreaking research in whole-organism cryopreservation & revival)

not one you will want to miss 🥶

[Kai Micah Mills @kaimicahmills]

hard to find better branding than HydraDAO, absolute masterclass by @SiMaclennan

the vision behind it: https://t.co/tSpCYz1uKk

[Hyrum Wolf @HyrumWolf]

Over $4M raised for whole-body replacement

To this day, HydraDAO @daohydra is one of my favorite portfolio growth projects

Today in the lab, we are transecting and fusing spinal cords, bringing humanity one step closer to using whole-body replacement as a medical treatment

[HydraDAO @daohydra]

HydraDAO: HYDRA-7: Kind Bio Integrated Organ Networks has PASSED

Bodyoids are a go🫘❤️‍🔥

https://t.co/L66yPC9jDY

[Avi Roy @agingroy]

Medicine has mostly treated a lost body part as gone for good. That is quietly changing. Some tissue is now being regrown in living people.

Ranked by how far along, humans first:

1. Cornea. A therapy called Holoclar uses a patient's own eye stem cells, grows them in a dish, and rebuilds a cornea damaged by a chemical burn. About 77% of eyes recovered, and the results held for ten years. Already approved.

2. Hearing. A gene therapy from Regeneron delivers a working copy of a broken hearing gene into the inner ear. In its trial, 11 of 12 children born deaf gained hearing, and three reached near-normal levels.

3. Teeth. A Japanese antibody wakes dormant buds for a third set of teeth. It cleared its first human safety trial, and a study in children born missing teeth comes next.

4. Sight. Stem-cell and gene therapies are restoring vision in macular disease, with roughly ten letters gained on an eye chart. Still early trials.

5. Heart muscle. The first patches of lab-grown heart cells are being tested in people in Japan, with modest benefit so far.

6. Limbs and whole organs. Still regrown only in salamanders and mice.

Caveats: The universal wins, teeth and hearing, are early or fix a single broken gene. Regrowing a whole limb or a failed heart is still an animal story.

For most of medicine, lost has meant gone. For a cornea, an ear, and soon maybe a tooth, that is no longer true.

[Kai Micah Mills @kaimicahmills]

mouse bodyoids are already here

large animal models are up next

🫘

https://t.co/VYrmiKcDPc

[HydraDAO @daohydra]

What you really want is a Bodyoid, you just don't realize it yet

[Bryan Johnson @bryan_johnson]

I just cloned myself...as a newborn

With this clone, I can:

+ become my own blood boy
+ test therapies on the clone
+ grow organs for transplantation
+ develop new treatments
+ inject young cells

This baby-bryan lives in a petri dish for now.

This may be scary to some people…a dystopian future. But, for others, they will see it as the inevitable future of health.

Clinical trials are already using this technology to restore dopamine neurons for Parkinson's, heart health and eyesight.

The process
> blood draw
> my cells were extracted
> yamanaka factors applied
> reset epigenetic age
> restoring them to an embryonic-like state

Why?
> these cells are now pluripotent
> can be differentiated into hundreds of cell types
> i.e. neurons, cardiomyocytes, retinal cells, etc
> allowing me to rebuild my body
> organ by organ
> repairing lost eyesight or hearing
> restoring kidney, liver or lung function
> repairing skin damage
> there’s no real limitation in imagining
> my body will accept them bc they’re my cells
> foreign cells are at risk of being rejected

As cells age, they accumulate epigenetic errors compounding into dysfunction and disease.

This technology gives us a path to reverse aging.

I mentioned getting diagnosed with an incurable disease is one of the best things that has happened to me in a long time. It’s opened up a frontier of new paths to repair and strengthen the body. This is the first example.

[RobLogic @RobLogic]

This tiny freshwater hydra snatches a wriggling snack with its tentacles in seconds… then casually grows a whole baby from its side

[Eli Mohamad @elimohamad]

Replacement parts on demand. Organ banks. No immune rejection, because they are your own, young organs. Nobody needs to die just because you need a transplant. @daohydra rising

[Kris Borer @krisborer]

Death should be optional. If you want to do something about it, check out my new book Radical Life Extension: Technological Strategies to Defeat Aging. ❄️🫀🧬

[Kai Micah Mills @kaimicahmills]

we are investing $250,000 into bodyoid research via hydra (@daohydra)

bodyoids, or integrated organ networks, can unlock perfectly matched organs and tissues on demand and alleviate suffering on a global scale

they are a key component in radically extending the human lifespan

along with our breakthrough spinal fusion research, we are filling in the gaps for whole-body replacement one by one

details to follow

[HydraDAO @daohydra]

Remember to be Kind to one another. You only have one life to live.

For now.

[Eli Mohamad @elimohamad]

You can make organs more resistant to various stresses ex vivo. In the future, we'll have replacement part banks with thousands of organs, and for those who can afford it, their own grown younger organs (no rejection risk).
We built @cryodao and @daohydra to address the key bottlenecks on this path: accelerate cryopreservation and replacement technologies.
And soon, we'll be able to engineer humans for cryosleep, enabling deep space missions.

[Andrei Panferov @andreypnfrv]

Medical Express mentions our experiments with spinal cord fusion :) Proud!

https://t.co/X421YG9sur