Darshak Bhatt

Postdoc @UMCG. Board member @SynBio_NL Interested in Synthetic Biology and Tumor Viro/Immunotherapy. Photography and drawing for fun.

[Darshak Bhatt @DarshakWrites]

3/3 This work was carried out at the labs of Luciana Andrade and Roger Chammas at @FMUSPoficial ICESP in Brazil, and with Toos Daemen in @researchumcg Groningen. 🎉 Shout out to all the coauthors that contributed to a great team effort!

[Darshak Bhatt @DarshakWrites]

1/3 Happy to share one of the final chapters of my PhD on oncolytic virotherapy! This study explores how oncolytic virotherapy can impacts the content and function of extracellular vesicles (EVs) from melanoma cells.

Link: https://t.co/TN0aHaUi8i

[Darshak Bhatt @DarshakWrites]

2/3 Key findings:
1. A single-round of infection with a recombinant alphavirus enables EV analysis without extracellular virus interference.
2. Oncolytic virotherapy alters EV cargo, including regulatory microRNAs.
3. EVs from infected cells reduce immune suppression.

[Darshak Bhatt @DarshakWrites]

🎉 Shout out to our awesome supervisors #FranjoWeissing and #toosdaemen for their guidance ���, and to @thijsjanzen for developing this amazing computational model #Spatialmodel #oncolyticvirus #Stochasticity 💻🎉

[Darshak Bhatt @DarshakWrites]

🥳Happy to share our article on oncolytic virotherapy and T-cell responses influencing outcomes. Key insights: timing of therapy, anticancer T-cell activity, and the diffusion of immune signals all play complex roles, sometimes reducing effectiveness.
https://t.co/6jUUAnvGkk

[Kevin Mitchell @WiringTheBrain]

My take on scientists leaving Twitter/X: It's great to see communities really developing on other platforms and there are lots of good reasons to boycott this place... 1/n

[Marjolein Crooijmans @MECrooijmans]

Bacterial cell wall, biofilm and morphology enthusiasts - our new preprint shows how E. coli manages to survive without its essential cell wall! Check it out 👇#microbiology #bacteria
@LeidenBiology
@ClaessenLAB
@HandeWinde

[Amélie Cabirol @AmelieCabirol]

✨#Postdoc opportunity in my lab @CbiToulouse ! Join an exciting @ERC_Research funded project on the microbiota-gut-brain axis in bees.

👉Apply: Portail Emploi CNRS - Offre d'emploi - Postdoctorat (H/F): Impact du microbiote intestinal sur la cognition des abeilles

[Joe Bondy-Denomy @joeBondyDenomy]

Did you know that bacteria remember their past for many generations? In this new preprint from us (@VillaniAlexis and Senen Mendoza) and Banin lab (@ShmidovE ), we reveal the "how?" and "why?" underlying a long-standing mystery in bacterial memory. https://t.co/zFc8PDLqTu

[Sonja Billerbeck @billerbeck_s]

Thanks for assembling this collection @DSchindler_PDR !
In our Chapter 15 you find methods to clone cost effective libraries with #oligopools and #GoldenGate by @Alicia_MV_ @_rprins and Thijs de Vroet 🧬🧬🧬

[Dagmar Wachten & lab @DagmarWachten]

Preprint from our #optogenetics team: novel photoswitch that allows an up to 400-fold induction of target gene expression by blue light! Perfectly suited to express biotherapeutics! Great collaboration @IIIBonn @MoeglichLab #ningaloobiosystems https://t.co/KdURxaWnUB

[Evan Weber @EvanWeberPhD]

An absolutely bonkers stat from this Nature article on Nobel Prize winners.

"702 out of 736 researchers who have won science and economics prizes up to 2023 are part of the same academic family"

https://t.co/qC3AeqwnSM

[Joseph Fasano @Joseph_Fasano_]

This is everything. In 2006, students from Xavier High School in NYC sent Kurt Vonnegut five letters asking the writer to visit their class. What he wrote back is one of the best things ever:

[Cauã Westmann @Cauawest]

I’m excited to announce that I’ll be defending my PhD next Wednesday (Oct 2nd)! If you're interested in molecular evolution and gene regulation and would like to join via Zoom, feel free to PM me for the link 😃

[Olivier Borkowski @O_Borkowski]

Microbial life in slow and stopped lanes
https://t.co/yapDq3bTdq

[Olivier Borkowski @O_Borkowski]

Now in @NatureComms :
Measuring the burden of hundreds of BioBricks defines an evolutionary limit on constructability in synthetic biology
https://t.co/EIearA1bj1

[Cees Dekker @cees_dekker]

I updated our webpage for openings at our #CDlab:
https://t.co/KYPrWGziVE

So feel free to apply if you are an ambitious young scientist interested in doing a postdoc (or PhD) in our biophysics lab!

RT=nice!

[Loai Abdelmohsen @AbdelmohsenLab]

We are thrilled to present our latest paper in @ACSCentSci, in which we demonstrate how communication between liposome artificial cells leads to the dynamic spatiotemporal organization of compartmentalized DNA. @chemical_llopis @vanhest_lab https://t.co/2LRJE5cdAn

[Rik Lindeboom @RLindeboom]

I'm #hiring a PhD student! Join the Lindeboom Lab at the @NKI_nl on an exciting project to explore oncogenic transcription factor binding kinetics and biophysics using state-of-the-art technologies! Apply now or share this exciting opportunity! https://t.co/ojFEKTkxgt