David Gilot

Cell Biologist interested in innovative therapies: ASO, siRNA and gene editing, Personal views.

[Neville Sanjana @nevillesanjana]

🚨🚨🚨 Thrilled to share our newest study — identifying functional long noncoding RNAs using transcriptome-scale RNA-targeting CRISPR screens.
🔎🔎🔎
We hope this scalable approach will be helpful for folks who want to connect noncoding RNAs to phenotypes & diseases.

[Rory Johnson @_Rory_Johnson_]

**please share** #Opportunity We are hunting for a special #CEO to drive an exciting project to develop new #rna medicines for #cancer patients

[GOLD Lab @GOLDLab_UCD]

🦋📷👑🦘#postdoc #opportunity alert! interested in joining us to develop exciting #RNA #cancer #crispr projects? Fellowship call open at https://t.co/SrN0TMvGnh Deadline 12 Oct

[Andrea Ventura @aventura71]

*Exciting

[CRISPR News 🧬 @CRISPR_News]

Major breakthrough: #CRISPR researchers have engineered a rice variant 🍚 resistant to multiple pathogens, including the devastating rice blast fungus, without reducing yield. A revolution for global food security as rice is a staple for 1/2 of the world. https://t.co/kWQEts5UVs

[Kévin Lebrigand, PhD @kevinlebrigand]

Spatial isoform Transcriptomics (SiT) is now published in @NAR_Open.
Combining @10xGenomics #Visium and @nanopore long-read, we explore the spatial landscape of gene expression isoforms in mouse brain sections.
@pbarbry @joalunatkthse @fr_genomics @CNRS

https://t.co/1PAKpKJXp3

[David Gilot @david_GILOT]

Thrilled to share our work on Gene Editing for #GM1 #gangliosidosis. Base Editing seems to be an alternative approach to treat patients @CureGM1
by ⁦@Delphine_Lclrc⁩ : She is looking for a PostDoc position !!!!!
@Inserm, ⁦@CSignaling⁩ https://t.co/5VhXkF4Lbd

[David Gilot @david_GILOT]

Wouaw Gene editing in Plant : Simplement génial . https://t.co/Ex1IDvLfJC

[Be the change you want to be @AgBioWorld]

@FAO releases a report on gene editing in ag. @doudna_lab writes “we can alter nutritional content to combat malnutrition, remove toxins from staple foods, increase yields to fight hunger, improve pest resistance, reduce the need for agrochemical inputs.

https://t.co/FdisdLPaRm

[David Gilot @david_GILOT]

From Rennes, France

[John Evans @john_evans3]

Inspiring and hopeful clinical case out of England - and the first human clinical proof of concept for base editing!!

https://t.co/Nh2PuyKqPK

[Morillon’s lab @LabMorillon]

An amazing line up of speakers for a free-access conference in Paris. Register here to secure a seat:
https://t.co/qj710OozVX

@SFCancer75
@andrzejDziembo1
@MaiteHuarteLab
@torbenheick
@ClaudiaKutter
@NovoaLab
@vanHeeschLab
@HowardYChang

[David Gilot @david_GILOT]

@CSignaling @CoulouarnC @Inserm Bien mérité Cédric Bravo.

[David Gilot @david_GILOT]

@GeneInvesting So sad for Rich Horgan and his family 😪

[GOLD Lab @GOLDLab_UCD]

GOLD Lab is hiring! We seek talented and ambitious young scientists for cutting-edge experimental AND quantitative/computational projects at PhD/postdoc level. Details here: https://t.co/ECBKuBw1QW **please retweet / share**

[David Gilot @david_GILOT]

Smart & efficient 🤩

[Madelynn Whittaker @mn_whittaker]

Interested in CRISPR and Huntington’s disease? Check out this @jclinicalinvest paper: an allele-specific strategy targeting mutant HTT via nonsense-mediated decay! 🧬 ✂️ https://t.co/tYToyZNRaj

[For Women in Science @4womeninscience]

Les #FemmesEnScience et leurs contributions à un monde vivable, durable et inclusif méritent de rayonner 👩‍🔬

À travers leurs travaux innovants, six Jeunes Talents 2022 #FWIS @FondationLOreal-@UNESCO sont au cœur de la lutte contre des maladies rares, génétiques et cancéreuses �Les #FemmesEnScience et leurs contributions à un monde vivable, durable et inclusif méritent de rayonner 👩‍🔬

À travers leurs travaux innovants, six Jeunes Talents 2022 #FWIS @FondationLOreal-@UNESCO sont au cœur de la lutte contre des maladies rares, génétiques et cancéreuses �Les #FemmesEnScience et leurs contributions à un monde vivable, durable et inclusif méritent de rayonner 👩‍🔬

À travers leurs travaux innovants, six Jeunes Talents 2022 #FWIS @FondationLOreal-@UNESCO sont au cœur de la lutte contre des maladies rares, génétiques et cancéreuses �Les #FemmesEnScience et leurs contributions à un monde vivable, durable et inclusif méritent de rayonner 👩‍🔬

À travers leurs travaux innovants, six Jeunes Talents 2022 #FWIS @FondationLOreal-@UNESCO sont au cœur de la lutte contre des maladies rares, génétiques et cancéreuses �Les #FemmesEnScience et leurs contributions à un monde vivable, durable et inclusif méritent de rayonner 👩‍🔬

À travers leurs travaux innovants, six Jeunes Talents 2022 #FWIS @FondationLOreal-@UNESCO sont au cœur de la lutte contre des maladies rares, génétiques et cancéreuses �Les #FemmesEnScience et leurs contributions à un monde vivable, durable et inclusif méritent de rayonner 👩‍🔬

À travers leurs travaux innovants, six Jeunes Talents 2022 #FWIS @FondationLOreal-@UNESCO sont au cœur de la lutte contre des maladies rares, génétiques et cancéreuses 👏

[David Gilot @david_GILOT]

@Delphine_Lclrc @FondationLOreal @UNESCO @4womeninscience @CSignaling @InsermGrdOuest @Inserm @Eugene_Marquis @UnivRennes1 @CHURennes Quel immense bonheur de voir ton travail et ton sérieux récompensés !! Ton intelligence te permettra d'accomplir tes rêves. Félicitations.

[Yair Einhorn @yaireinhorn]

4/These profound reductions in serum TTR were sustained throughout the observation period - ranging from 2 to 6 months.The data supports $NTLA-2001 as a one-time treatment to permanently inactivate the TTR #gene thus reducing the disease-causing protein in patients with #ATTR-CM.

[David Gilot @david_GILOT]

Congrats Sebastian & Yannick for this Tour de force 💪

[Sébastien Levesque @SbastienLevesq4]

Our work @doyonlab is officially out @NatureComms! Here’s a thread on how co-selection facilitates prime editing (PE) in human cells and how we uncovered previously unappreciated PE3-mediated DNA repair outcomes. https://t.co/jgMZlXyFqd