Our most recent Nature Cell Biology paper describes an innovative Perturbation-response Score (PS) method to decode heterogeneous responses of cells to perturbations at single-cell level. Particularly helpful for analyzing Perturb-seq data. https://t.co/KaMvUj7ovH
Also, especially shout out to the scGPT tool built by @BoWang87. It would be much more difficult to build our model without the wonderful, open-source scGPT!
Perturbation-prediction AI models are critical for building virtual cells. Many models exist, but what is next? What is the critical gap to application? Our pertTF preprint shows the next step: cross-system prediction, and beyond gene expression. https://t.co/b28JUZoA8Y
@xinjin@NVIDIAHealth Really incredible resource to understand brain function and great for the AI community. Thanks for releasing all these wonderful datasets!!
Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.
Perturb2026 is an exciting conference about generating perturbation data, building AI models, and interacting with academic and industry attendees. Great lineup of speakers. Come and join us on March 18-19, Vienna, Austria! https://t.co/W4wYXO2nqG
🧬 Building the Virtual Cell starts with data.
Today, we’re making the X-Atlas/Orion Perturb-seq dataset even more accessible — now live on Hugging Face @huggingface 🤗
📊 One of the largest & highest-quality perturbation datasets ever released, it provides the foundation for training AI models that can simulate and reason about cellular behavior.
👉 Explore here: https://t.co/0bszMU32nT
Fewer barriers. More models. A step closer to the virtual cell. 🌌
#VirtualCell #FoundationModels #AIinBiology #HuggingFace
#CSHAsia Course on #CRISPR#Genome Engineering: Basics, Applications and Future Directions
⌛️Application is still available by Aug. 25
📍Suzhou, China
📅October 9-19, 2025
🎯Undergrad/graduate students, postdoctoral fellows, scientists and professors
Our Cell paper is online (https://t.co/t5bOxlCN8q)! We present the CIDE framework, broadly applicable to cancer research and oncology. Also, we highlight AOAH as a promising new immunotherapy.
@BaoxuP Also immediately after this course (Oct 9-19) is the CSHA "Systems Biology of Gene Regulation and Genome Editing" conference (Oct 20-24). Great opportunity to attend both events in one place! @CSHANews
We are delighted to organize this CSHA inaugural CRISPR course, this October, at the beautiful Suzhou City, China. Great opportunity for trainees/researchers to learn everything about genome engineering and interact with top scientists in the field. App ddl Aug 8.
🎉 Join us in welcoming Dr. Wei Li as Associate Professor in Pharmacology & Physiology at UMSOM!
His groundbreaking work in AI, CRISPR, and cancer biology is driving the future of precision medicine. Welcome aboard, Dr. Li! 👏🔗 https://t.co/a2woRczDNw