deWitLab

Computational & Genomics Lab studying 3D genome function and dynamics @ Netherlands Cancer Institute

[deWitLab @deWitLab]

You may know ZNF143 as a looping factor. We show together with the @hansen_lab that this is not the case! If you want to know why and what it does instead do read our thread below:
https://t.co/2oPbiy0SoW

[Luca Braccioli @LucaBraccioli]

📢 We are very excited to announce the first International Dutch Embryo Model Meeting in Nijmegen on March 27-28. See below for details.

Don't miss this fantastic opportunity to connect with the embryo model community!

[Anders Sejr Hansen @Anders_S_Hansen]

Come and join us!

[Tineke Lenstra @tinekelenstra]

Check out our latest review on how cooperativity influences transcriptional bursting. Kudos to the first author Charis Fountas! https://t.co/TEXbncV4J7

[Eda Yildirim @YildirimLabDuke]

Delighted to see the completed Special Issue of Current Opinion in Genetics and Development on "Genome Architecture and Expression”

It was a pleasure putting this together with Maya Capelson.

Thanks to all the authors that contributed articles

https://t.co/RQI7HBy6uZ

[deWitLab @deWitLab]

@Anders_S_Hansen @NIH_CommonFund Wow, congrats! Hope this leads to loads of cites 😆

[The Netherlands Cancer Institute @NKI_nl]

The protein factories of our cells are much more diverse than we thought. NKI scientists have shown that cancer cells can use ribosomes to boost their invisibility, helping them hide from the immune system. They publish their findings in Cell today ➡️ https://t.co/HiwoYct5DA

[The Netherlands Cancer Institute @NKI_nl]

Researchers from the Netherlands Cancer Institute and @prinsesmaximac are launching a new study looking into rhabdoid tumors, a rare and highly aggressive form of childhood cancer, thanks to financial contributions from @kika8118 ➡️ https://t.co/sIW8eQGmdd

[Geoff Fudenberg @gfudenberg]

Happy to share work with Hadi, Yao & @Maxime_Tortora characterizing the impact of dynamic CTCF barriers for cohesin loop extrusion
https://t.co/iiaiJg2ZeB

[Rob Klose @RobKlose]

Want to do a DPhil @BiochemOxford ? Here is a link (https://t.co/91DzUxEkId) to programmes that admit students. Great labs to choose from. Have a look at https://t.co/xRFjpV4GRP if you want to know more what we do in my group! Please RT!

[Antoine Zalc @AntoineZalc]

🚨🚨🚨
Call is now open!!!
Wanna become our new beloved colleague 🫶🏻🫶🏻🫶🏻 and be part of a stimulating (and friendly) scientific community ???
We are perfectly located in beautiful Paris with exciting work environment and state-of-the-art core facilities
APPLY 👇🏻👇🏻👇🏻👇🏻

[The Netherlands Cancer Institute @NKI_nl]

👀 We're looking for a junior group leader! Join our innovative, curiosity-driven institute in a collaborative, international environment. Full freedom to pursue your research, competitive salary & relocation support.

📅 Apply by Dec 1
Info & application: https://t.co/my1GSyAsQy

[deWitLab @deWitLab]

@NicolaFestuccia On Oct 4 no less, congrats!

[Elphege Nora Lab at UCSF @ElphegeNoraLab]

First preprint from the lab 🚨

How can enhancers regulate target promoters across vast genomic distances, and what is the role of cohesin loop extrusion in the process?

https://t.co/l7bwPsTSkd

(1)

[Leila Akkari @LeilaAkkari1]

Paper 🚨! Ecstatic, proud, grateful …Years of dedication from the whole lab, with the exceptional @djkloosterman and the one of a kind #JohannaErbani at its helm. What a journey all the way to @CellCellPress! How did it start (& end)? A 🧵1/n
https://t.co/d1SPgjFRDr

[Lea Kiefer @LeaKiefer138]

(1/16) Check out our @SimonMJGaudin paper https://t.co/ZcCmKI4CFh from the Canzio lab out in @ScienceMagazine today on how tuning local cohesin trajectories enables differential readout of the clustered Protocadherin (Pcdh) locus across different types of neurons.

[Rik Lindeboom @RLindeboom]

I'm #hiring a PhD student! Join the Lindeboom Lab at the @NKI_nl on an exciting project to explore oncogenic transcription factor binding kinetics and biophysics using state-of-the-art technologies! Apply now or share this exciting opportunity! https://t.co/ojFEKTkxgt

[The Netherlands Cancer Institute @NKI_nl]

Immunotherapy before surgery for patients with metastatic melanoma appears to be successful as 59% of patients responds so well that adjuvant treatment is no longer needed, show the results of the NADINA trial presentend at #ASCO24 today by @ProfCUBlankNKI https://t.co/f4ATt0Mi2g

[Jan Kosinski @jankosinski]

Might attempt to model a flotillin cage using the AlphaFold3 web server was super fun (original paper: https://t.co/zLldiN2BHR). Read the thread for a crazy plot twist!🧵👇

[Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social @RolandDunbrack]

Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get @Nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? @GoogleDeepMind

[Andrew Wood @AndrewWoodLab]

Interested in using degron tagging to study the function of your favourite protein in genetically engineered mouse models? Check out our review covering recent work in this area: https://t.co/9DKLmjaH5h