deGrootLab

Group of SELF-ORGANIZATION IN BIOLOGICAL SYSTEMS
Lead by Natalia Sánchez de Groot
@UABBarcelona

[deGrootLab @degrootlab]

After a long journey, it’s out.
Can prion-like proteins from the gut microbiome trigger neurodegeneration?
"Exogenous prion-like proteins and their potential to trigger cognitive dysfunction" 🧠🦠 | Molecular Systems Biology https://t.co/aCBREIw5CI
#Neurodegeneration #Microbiome

[ShorterLab @ShorterLab]

Global analysis of protein degradation reveals instability of diverse regulators in Escherichia coli | PNAS https://t.co/vp5pxSOEAp

[ShorterLab @ShorterLab]

The Alzheimer’s disease risk genes MS4A4A and MS4A6A cooperate to negatively regulate TREM2 and microglia states: Neuron https://t.co/ZjIGKj7FxA

[ShorterLab @ShorterLab]

Mast cell extracellular granules are bioactive condensates assembled by heparin and polyamine: https://t.co/cZeypMowH6

[Serpell Lab Reads @SerpellLabReads]

Sequence‐Driven Modulation of the Multistage Self‐Assembly Process in Lamellin‐Type β‐Peptides https://t.co/YgHUy3oSV7

[ShorterLab @ShorterLab]

A proteome-wide dependency map of protein interaction motifs: https://t.co/BiqnLTHt7w

[ShorterLab @ShorterLab]

Neurons with granulovacuolar degeneration bodies are resilient to tau-induced protein synthesis impairment | Science Advances https://t.co/aKXd07mtG4

[John Damianos, M.D. @john_damianosMD]

More evidence that stool microbiome testing is not ready for prime time yet!

[Serpell Lab Reads @SerpellLabReads]

Cell-penetrating peptides for therapeutic applications: emerging design strategies and future directions https://t.co/l2jpDtDA6s

[Sauralab @sauralab]

Interested in a postdoc position to investigate metabolic cell vulnerability in #Alzheimer disease? Apply with us to Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2026 | Send CV and short project/idea to @CarlesSaura [email protected]
https://t.co/s5GHENxcqp

[Gut Microbiota for Health NW @GutMicrobiotaWW]

Not all #microbiome science is ready to apply in your daily life

@MireiaVallesc explains what we know and do not know about the #microbiome today and how new research could lead to better treatments in the future

👉 Learn more here:

https://t.co/omQJshLkus

[ShorterLab @ShorterLab]

Could targeting viruses be a new hope against neurodegenerative diseases? https://t.co/9ULvSSSICc

[DARWIN Bioprospecting Excellence @DarwinBioprosp]

Venya Patel wrote an excellente piece on Nutrition Insight, highlighting our latest paper research on the microbial diversity of traditional Ethiopian foods. Check the link below to find out more.

https://t.co/MkvAUahXyq

[ShorterLab @ShorterLab]

Exogenous prion-like proteins and their potential to trigger cognitive dysfunction | Molecular Systems Biology https://t.co/GIPryYrSpX

[brangwynnelab @brangwynnelab]

What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity to find out - Biggest surprise was impact of encoded protein function. Fantastic work w/ @LindsayABecker @sofiquinodoz @david_a_knowles
https://t.co/3EG8ntIZYY

[deGrootLab @degrootlab]

Thanks to: Ann Hochschild, Padraig Deighan, Rafael Giraldo (@rafgir63), Antonela Lavatelli, Julian Cerón (@CeronLab), Antonio Miranda (@AMV_REDOX), Anna Laromaine (@alaromaine), Esther Dalfo (@EstherDalfo), Gian G. Tartaglia (@tartaglialab), Nuria Benseny, Josep Cladera 🙏

[deGrootLab @degrootlab]

After a long journey, it’s out.
Can prion-like proteins from the gut microbiome trigger neurodegeneration?
"Exogenous prion-like proteins and their potential to trigger cognitive dysfunction" 🧠🦠 | Molecular Systems Biology https://t.co/aCBREIw5CI
#Neurodegeneration #Microbiome

[deGrootLab @degrootlab]

First big project as a PI. New lab, new topic, tons of unknowns. So grateful to everyone who helped make this happen.

[deGrootLab @degrootlab]

🧠🦠 Spoiler alert:
Yes, gut microbes may carry prion-like proteins.
We identified sequences in H. pylori that form amyloids, affect Aβ aggregation, and trigger memory defects in worms.
The gut is a gateway to the brain, and to neurodegeneration.

https://t.co/c0KuH7TL11

[deGrootLab @degrootlab]

After a long journey, it’s out.
Can prion-like proteins from the gut microbiome trigger neurodegeneration?
"Exogenous prion-like proteins and their potential to trigger cognitive dysfunction" 🧠🦠 | Molecular Systems Biology https://t.co/aCBREIw5CI
#Neurodegeneration #Microbiome

[BCT UAB @Bctuab]

@uabbiociencies @UABciencies @EnginyeriaUAB @matdepuab @MatCAD_UAB @matesAbeam @iec @soccatmat

[Asociación RUVID @asociacionruvid]

🔴 @Repsol invierte en @DarwinBioprosp, #Spinoff de la Universitat de València, y le transfiere una innovadora solución de #Biotecnología https://t.co/7QR9bCb79d

@CdCienciaUV @parccientificuv