Dex

Your AI workspace in Chrome.
Build agents across all your personal and team context.
Use them right where you already work.

[Dex @dexbythirdlayer]

Karpathy was right about personal knowledge bases for LLMs. But markdown files alone won't cut it.

Dex captures raw operational events - every Slack thread, email, meeting, deal update - and structures them into a live context graph that agents can reason over at scale.

Personal knowledge bases are for you to read.
Operational knowledge bases are for agents to act.

Get early access at joindex[dot]com

[Regina Lin @reggitales]

Introducing Dex: the self-driving workspace for operators.

Dex is the first agent system with full operational context and a self-updating knowledge base.

Every datapoint from your workspace is ingested, synced, and structured into compounding context for agents to take action.

Comment "DEX" or tag @dexbythirdlayer access.

First 1,000 sign-ups get 7 days free.
After, join our rolling waitlist.

Sign up at joindex [dot] com for a fun surprise.

How dex works (threads)

[Dex @dexbythirdlayer]

sat down with @notablecap to talk about what that bet actually looked like, and where we're taking it next.

Spotify: https://t.co/X6bp1CfuV1

Apple Podcasts: https://t.co/LOwWjrxUEX

YouTube: https://t.co/Ne6MSB7Iw3

[Dex @dexbythirdlayer]

four weeks before YC demo day, we killed what we'd been building. it had a 50% CMO response rate, but we couldn’t stop thinking about an idea that nobody had a name for yet…

10,000+ downloads later, that idea is Dex.

[Notable Capital @notablecap]

On the 1st ep of First Commit, @reggitales explains why she dropped out of Harvard, left a YC batch mid-pivot, and is now building Dex — a browser agent helping knowledge workers offload the manual layer of their day.

[Notable Capital @notablecap]

Introducing First Commit — a new Notable podcast series that talks to builders solving hard problems before the industry catches up.

First episode drops tomorrow with @reggitales, co-founder of @dexbythirdlayer.

[Dex @dexbythirdlayer]

We pitched AI coworkers at YC demo day before AI coworkers became the obvious direction notion, zapier, glean, everyone was racing into. Before that, we bet on computer-use agents before agents were a thing, and browser copilot before AI browsers existed.

Sat down with Notable Capital to walk through what it's like to give up everything, bet hard on something nobody else sees, be obsessed enough to do it anyway, and watch the world wake up to it in real time.

Now we’re betting on where it’s headed next.

[Laura Hamilton @lauraham150]

First episode drops tomorrow with @reggitales of @dexbythirdlayer. Subscribe and come find out how she’s building the self-driving workspace that lives in your browser🎙️

[Bain Capital Ventures @BainCapVC]

The AI chat box had a good run. So now what?

We’re tackling that question and more at Intent: Proactive & Predictive Interfaces, this Thursday.

@amandamhuang and @rkhkimx are moderating a stacked panel featuring Jenning Chen (@simile_ai), @KevinGu (@dexbythirdlayer), @justoutquan (Tomo) and @kneureither (@interaction).

May 21st, 6 - 7:30 PM | Co-hosted with @dexbythirdlayer
https://t.co/S1QXjHuauY

[Bain Capital Ventures @BainCapVC]

The gap between “I need to do X” and X getting done? That’s an interface problem.

We’re getting together this Thursday with founders and builders who are closing it.

Join us for Intent: Proactive & Predictive Interfaces, co-hosted with @dexbythirdlayer and moderated by BCV investors, @amandamhuang and @rkhkimx.

Doors open at 6 PM! Spots limited:
https://t.co/S1QXjHuIkw

[Regina Lin @reggitales]

Intent Series pt. 2 is this Thursday: Proactive & Predictive Interfaces. RSVP below.

Panelists:
Jenning Chen (Simile AI)
Kevin Gu (ThirdLayer)
Justin Quan (Tomo)
Konstantin Neureither (Interaction)

hosted with @rkhkimx & @amandamhuang and @aurielws

[Franco Farnedi @ffarnedi]

@reggitales done - [email protected]

[Kaushik Mahorker @kaushikm_]

Been using dex everyday for the past few weeks, and they have a killer hubspot integration so my CRM is always up to date

[Forsy @Forsy_AI]

NEW: @dexbythirdlayer is making the case for self-improving agents.

AutoAgent reportedly spent 24+ hours autonomously tuning an agent harness, then hit #1 on SpreadsheetBench (96.5%) and the top GPT-5 score on TerminalBench (55.1%).

Manual harness engineering is starting to get challenged by agents that optimize themselves.

[Aditi @music_adit17056]

been using @dexbythirdlayer for 3 months and ngl it feels like my own personal JARVIS atp

it reads and labels my emails, helps organize everything, and even plans meetings directly in my Notion calendar

As someone working in venture research, this tool is definitely staying.

[Edoardo Morani @ed_moraaaa]

Everyone should take a look about this product called @dexbythirdlayer

A self-driving workspace for operators

This is a very interesting tool btw that can literally make your work organization easier

[Dex @dexbythirdlayer]

Karpathy was right about personal knowledge bases for LLMs. But markdown files alone won't cut it.

Dex captures raw operational events - every Slack thread, email, meeting, deal update - and structures them into a live context graph that agents can reason over at scale.

Personal knowledge bases are for you to read.
Operational knowledge bases are for agents to act.

Get early access at joindex[dot]com

[Kevin Gu @kevingu]

introducing Dex, the first agent system with full operational context and a self-updating knowledge base

karpathy's llm knowledge base on steroids

Dex ingests raw events from every app in your workspace. every slack message, email, meeting, browser session, task update compounds into one living knowledge base. background agents continuously monitor and enhance it while you sleep so your agents get smarter every day

try now at joindex [dot] com

[Dex @dexbythirdlayer]

@reggitales https://t.co/gSRsR1130A

[Regina Lin @reggitales]

Introducing Dex: the self-driving workspace for operators.

Dex is the first agent system with full operational context and a self-updating knowledge base.

Every datapoint from your workspace is ingested, synced, and structured into compounding context for agents to take action.

Comment "DEX" or tag @dexbythirdlayer access.

First 1,000 sign-ups get 7 days free.
After, join our rolling waitlist.

Sign up at joindex [dot] com for a fun surprise.

How dex works (threads)

[Dex @dexbythirdlayer]

@reggitales dex it up

[Dex @dexbythirdlayer]

@calcsam @mastra HUGE

[Dex @dexbythirdlayer]

agent engineering can now be automated. this is the next step for agents to recursively self improve

[Kevin Gu @kevingu]

https://t.co/DBaiIhnhLQ