Dharmesh Patel

Assistant Prof@Emory, Computational Chemist/Molecular Modeler@LOBP, School of Medicine, Emory University #CompChem #gymgoer #Foodnerd #DrugDesign

[Living Journal of Computational Molecular Science @livecomsj]

We have a new paper out, on parameterizing modified nucleic acids for simulation in AMBER! https://t.co/dplTNlPi4f #compchem

[Dharmesh Patel @DharmeshJP]

🧬 Excited to share our new paper in J. Med. Chem.! We report novel dimeric capsid assembly modulators (D-CAMs) as a unique class of highly potent anti-HBV agents, with improved potency and distinct effects on capsid morphology. https://t.co/3bnKnWXJYl @ACSPublications

[Dharmesh Patel @DharmeshJP]

Using structure-based similarity of SARS-CoV-2 3CLpro, we identified other viral proteases with shared features. As predicted, NIP-22c and CIP-1 showed broad-spectrum antiviral activity against SARS-CoV-2, norovirus, enterovirus & rhinovirus. https://t.co/C4NxJhz8om

[Dharmesh Patel @DharmeshJP]

@EmoryUniversity @EmoryMedicine @EmoryPediatrics

[Dharmesh Patel @DharmeshJP]

Behind Our Published Paper: Loss of the Aryl Hydrocarbon Receptor promotes cancer cell resistance to BRAFV600E targeted therapies https://t.co/d97plDMztD #

[Dharmesh Patel @DharmeshJP]

Excited to share that our recent work is published in Nature - Sig Transduct Target Ther on “Loss of the aryl hydrocarbon receptor promotes cancer cell resistance to BRAFV600E targeted therapies.”https://t.co/l6sE66FJAK @EmoryMedicine @AtlPedsResearch @WinshipAtEmory

[Dharmesh Patel @DharmeshJP]

Check out our recent article on Combating yellow fever virus with 7-deaza-7-fluoro-2′-C-methyladenosine | Antimicrobial Agents and Chemotherapy https://t.co/bhyuHwt4xa @AtlPedsResearch @EmoryUniversity @EmoryMedicine

[Ilya Kuprov @Ilya_Kuprov]

We are trying to increase Computational Chemistry representation at @ScienceAdvances - if you work in that area, consider sending something. We do have Comp Chem specialists on the editorial board who would be able to judge a manuscript on its merits. https://t.co/mUm1tlY881

[AI Andy @ItsAIAndy]

MIT University is offering free online courses.

No payment is required.

Here are 9 courses you can't afford to miss in 2025:

[Dharmesh Patel @DharmeshJP]

Looking forward to work on drug discovery for cystic fibrosis! @AtlPedsResearch @EmoryCHOA_CFAIR @EmoryPediatrics

[Dharmesh Patel @DharmeshJP]

Check out our recent work on sustained antiviral insulin signaling during West Nile virus infection results in viral mutations https://t.co/TAH5uTqAeU @EmoryMedicine @EmoryPediatrics

[Gabriele Corso @GabriCorso]

My seminar on ML in Structure-Based Drug Discovery at the MoML Summer School is now on YouTube https://t.co/NEoDB67AaC
Giving this class had a particular significance for me as MoML is dedicated to the memory of Octavian Ganea an amazing friend who introduced me to this topic 🙏

[Dharmesh Patel @DharmeshJP]

Excited to be part of the team as a co-investigator, looking forward to working on antiviral targeting Mpox virus.

[Sarafianos Lab @SarafianosLab]

Thrilled to receive NIH funding for this collaborative effort with Ray Schinazi and Haian Fu on the discovery of MPOX virus-targeting antivirals! Grateful to the reviewers for appreciating the team's efforts and preliminary data.

[rcsb pdb 💉🧬💻🔬💊🌱🧠🦠 @buildmodels]

Soap molecules break up the outer layer of enveloped viruses stopping infection. Watch at the molecular level how soap breaks up viruses by using series of hydrophilic and hydrophobic interactions. #WorldHygieneDay
https://t.co/96KGXJ3hrn

[Dharmesh Patel @DharmeshJP]

Check out out recent work on Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections https://t.co/IiaxUfjWxu #mdpiviruses via @VirusesMDPI @EmoryMedicine @EmoryUniversity @EmoryPediatrics @EmoryBDCI @drugbuster21

[Dharmesh Patel @DharmeshJP]

Check out our recent work on Biophysics-Guided Lead Discovery of HBV Capsid Assembly Modifiers | ACS Infectious Diseases https://t.co/GNEFcfgrQa

[Dharmesh Patel @DharmeshJP]

@SarafianosLab There is another great story on SuFEx recently out by @HarborSpring https://t.co/x3DLQnRWZC

[Dharmesh Patel @DharmeshJP]

Check out our recent work on Synthesis and biological evaluation of novel Peptidomimetic inhibitors. NIP-22c displays nM activity and high potency against nirmatrelvir resistance mutants. @EmoryMedicine @EmoryUniversity @EmoryPediatrics https://t.co/lkBYcM1Rwd

[Dharmesh Patel @DharmeshJP]

Check out recent article. Synthesis and evaluation of highly potent HBV capsid assembly modulato... https://t.co/PyoKS6ILAz

[Dharmesh Patel @DharmeshJP]

@EmoryBDCI @EmoryCFAR @EmoryPediatrics @EmoryMedicine @EmoryUniversity Thank you!

[Dharmesh Patel @DharmeshJP]

I am excited to announce our patent on prediction of antiviral resistance mutations https://t.co/BlJ0A3pMMl @EmoryBDCI @EmoryCFAR @EmoryPediatrics @EmoryMedicine @EmoryUniversity