Congrats to Dylan and Stephen for their method to glycosylate cotylenol and access 14-3-3 protein-client molecular glues! https://t.co/oyBP8aF1NH
Donor linker design was aided by Stephen’s “autoDFT” and solved a common problem in terpenoid synthesis: contrasteric glycosylation.
Want to reduce an alkene? Don’t want to use H2 + Pd/C? Check out @sopoandy@mclerici123 and I’s recent publication on photochemical hydrogenation out now in @JOC_OL!! This is a practical and SAFE way to reduce highly substituted alkenes and heterocycles.
https://t.co/d0mEpryexC
Congrats to Prof. Benjamin Cravatt for receiving the 2024 Bristol Myers Squibb Award for Enzyme Chemistry from the @ACS_DivBioChem. His work in activity-based protein profiling revolutionizes treatments for neurological disorders and cancer. 🎉🌟 More at: https://t.co/07oQgCR7UZ
Congratulations to Ben Cravatt of @scrippsresearch on receiving the 2024 Bristol Myers Squibb Award in Enzyme Chemistry! The Cravatt lab has had substantial impacts ranging from fundamental research to advancing clinical candidates. Hear more during our symposium at #ACSFall2024!
Is everything bigger in #Texas?? Me & @BradMoore_SIO are stoked to unveil the “PKZILLAs”: Genes for the new largest known enzymes and proteins in #biology, from the Texan fish-killing alga Prymnesium parvum. PKZILLAs make their giant 90-carbon polyketide toxin, prymnesin! 🧵1/n
We are happy to start the Year of 2024 with a total synthesis of heilonine @J_A_C_S ! Cheers!
Convergent and Efficient Total Synthesis of (+)-Heilonine Enabled by C–H Functionalizations | Journal of the American Chemical Society https://t.co/xewLUOTAOL
@GriceChemistry Not the first I’m hearing about this but would love to learn more. Do you have any recommended reading on this topic that I could take a look at?
Cool to see Gavin’s awesome work highlighted in @OPRD_ACS! The article sold really say Smith and coworkers as this was all him. Congrats and if anyone in industry is looking for a fantastic chemist let me know so I can connect you.