ER arrival sites associate with ER exit sites to create bidirectional transport portals | Journal of Cell Biology | Rockefeller University Press https://t.co/eG6A1Og2D8
Is it possible to use ‘Reprogramming of organelle morphology’ such as primary cilia length as a therapeutic approach or as a pathway to drug discovery? Please check this out.. https://t.co/3omslNFTXr
Samruddhi Shembekar, Martin Bähler and colleagues interrogate the regulation of mitochondrial cristae organisation by Myo19, Miro1 and Miro2, and metaxin 3.
https://t.co/fSf3ETc3Uk
#JCSMitoSI#mitochondria#OpenAccess#ReadandPublish
Jason Casler @JasonCasler1, Clare Harper and Laura Lackner find that mitochondria–plasma membrane contact sites regulate the ER–mitochondria encounter structure.
https://t.co/Z7g4zSKvDf
#JCSMitoSI#OpenAccess#ReadandPublish
The small #GTPases Arf1-5 are important regulators of membrane traffic and #Golgi functions. Pennauer, Spiess et al. @biozentrum analyze viability and phenotypes of individual and combined CRISPR/Cas9 Arf knockout cell lines. https://t.co/0ZMBfR5zj2
#Trafficking#organelles
How do brains rewire throughout life?
Our paper out in @Nature today outlines several principles of brain circuit development that we found by mapping the complete wiring of eight brains.
https://t.co/C2k8xv7mVp
#neuroscience#connectomics#brain#neurons#celegans#science
To explore the genetics that determine the differences between forewings and hindwings a team of scientists, including MBL's Nipam Patel (@Parflyale) and @AaronPomerantz, used CRISPR-Cas9 genome editing to disable a Hox gene in three different species. https://t.co/Z6jkujN99D
News & Views: Damage to DNA in a cellular organelle called the mitochondrion triggers an immune response in the nucleus. Mechanistic insights into this process published in Nature shed light on how organelles communicate. https://t.co/A77wpv0hYn
A new method allows researchers to analyse the dynamics of immunological synapses while avoiding the limitations of fluorescence microscopy. The approach combines deep learning algorithms and a 3D imaging technique called optical diffraction tomography https://t.co/nUZzyOJ2Uz
"The authors provide the first 3D reconstruction of the entire #microtubule network in primary mammalian cells." A JCB study (https://t.co/CgCgTg5JG0) by @Andi_Microscopy, @msolimena, et al. highlighted in @Facultyopinions: https://t.co/D3Oq4GhrC3
#TechnicalAdvance
A study in Nature describes how to engineer nanoparticles so that they exhibit “photon avalanching,” a disproportionately bright response to excitation that can be harnessed for superresolution imaging. https://t.co/a34YCBZrL5
Today would have been the 100th birthday of Shinya Inoué, pioneering innovator in microscopy and live-cell imaging and beloved MBL scientist. 🔬
📸 by Tom Kleindinst
https://t.co/XU8QfDvtzQ
Happy New Year! The station orbits the Earth at 17,500 miles per hour (28,000 kilometers per hour) enabling the crew to see 16 sunrises and sunsets each day.
Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on #Golgi structure, say Yijun Zhang and Joachim Seemann @UTSWNews: https://t.co/zRsIlhKskX
#Organelles