Diego M. Riaño-Pachón

professor, biologist, bioinformatician, skeptic, atheist, easy going

[Michael Schatz @mike_schatz]

So long San Diego! Here’s my opinionated meeting report from #PAG2025 | #PAG32. What else did I miss???

[The Biodiversity Genomics Academy @TheBGAcademy]

It's the 6-week countdown to BGA24, and we currently sit at 30 unique sessions!

You can join us at https://t.co/h2JwerRiIt to keep up to date with information and other attendees!

Session list: https://t.co/plaib455rU

#BGA24 #Bioinformatics #Biodiversity #Genomics

[Diego M. Riaño-Pachón @diegoriano]

Verifying myself: I am diriano on https://t.co/zimthVLniP. 1cK0C4kph4tq8Ijew50HxCjEkP0JofdbE25l / https://t.co/3PPeOaPPYX

[Massimo @Rainmaker1973]

If you think overpopulation is a problem, you may be wrong.

Two centuries of rapid global population growth are coming to an end.

World population growth is a first derivative, in math terms, and peaked in 1968, going down almost continually ever since

UN projections show it will possibly falling below 0.1% in 2100.

[📉 Our World in Data]
[read more: https://t.co/yfCZ2krs64]

[Sophien Kamoun @KamounLab]

Early days of de novo genome assembly

[𝕐 @nomad421]

K&R is, in fact, the only correct style for placing { and }.

[Linus ✦ Ekenstam @LinusEkenstam]

GitHub re-founded on Copilot 🤯

Everyone will be able to write code. I'm certain.

Todays upgrade to Copilot is a push in that direction

[Omar Abudayyeh @omarabudayyeh]

We’ve always wondered if there was something beyond CRISPR for genome editing. We now report that animals, plants, fungi and viruses have troves of programmable nucleases capable of efficient gene editing in human cells

An update on our Fanzor work!

https://t.co/9oAJFDmOpH 1/7

[Taco Jesse @TJesse62]

PacBio vs Nanopore
@PacBio
@nanopore

- Final version -

Acknowledgements to @khmiga

[Federico Brown @federico_brown]

Thanks to @mariana_deniz and @focalplane_jcs for the friendly interview and for allowing me to share my career path discovering the wonders of #evodevo. Special thanks to @Luiza_O_Saad, Denisse Galarza, and @JuanJimenezMer3 for the #planarian, and #ascidian microscopic photos.

[Mick W@tson ↙️ @BioMickWatson]

from: https://t.co/sIHAIrBAY6

[European Reference Genome Atlas @erga_biodiv]

Wondering how to best annotate #protein-coding genes in a genome? 🧬

Check out our new #structural annotation guide👉 https://t.co/szeLSBTmXL

Great work led by @ADennis1980 & the ERGA #Annotation Committee 🎉

@EBPgenome @BioGenEurope

[Heng Li @lh3lh3]

Pangene is a new tool for constructing a pangenome gene graph from multiple assemblies: https://t.co/0nAlftYxRF. You can explore the rich haplotypic diversity of human genes at https://t.co/3wXVcsjITJ. Still WIP.

[Heng Li @lh3lh3]

jstreeview is a HTML+JavaScript tree viewer/editor I initially developed for TreeFam in 2008. I now make it public with minor updates at https://t.co/tGrUUEcn0z. Although 15 years old, jstreeview still has features rarely seen in other web-based or even desktop tree viewers.

[LLM Security @llm_sec]

* People ask LLMs to write code
* LLMs recommend imports that don't actually exist
* Attackers work out what these imports' names are, and create & upload them with malicious payloads
* People using LLM-written code then auto-add malware themselves

https://t.co/Va9w18RpWu

[Diego M. Riaño-Pachón @diegoriano]

SAGB Agosto @labbces https://t.co/V3AHCWniOg

https://t.co/VakPM1DTkb

[Heng Li @lh3lh3]

@richard_durbin and I have been working on a review titled "Genome assembly in the telomere-to-telomere era". We have put the preprint at https://t.co/vKC09eV4rt. Let us know if you have comments or suggestions. We would really appreciate!

[marek mutwil 🇺🇦 @LabMutwil]

We are seeking an assistant/associate professor in bioinformatics/computational biology/AI in life sciences. https://t.co/g9IuX2n4AJ The position comes with an attractive start-up fund, remuneration, and a very generous funding system. P.s. the place in the pic is <1 hour away.

[Mark @Sanbomics]

RNAseq counting tools are not perfect. I simulated 240 GTEx samples to test multiple tools. Below I show the difference between actual and estimated counts for each simulated sample.

But, what is causing this? And will it affect differential expression? (1/7) #Bioinformatics

[Professor Booty PhD @ProfBootyPhD]

I think we need to talk about how devastating this cancer microbiome refutation paper from
@StevenSalzberg1
and colleagues is. It really speaks to how devoid of critical thinking and intellectual depth our glam publishing ecosystem has become. 1/n
https://t.co/wWsHTa4K8x