Erik Wright

Devotee of science, especially #microbes, #evolution, & #bioinformatics. Crew member on spaceship Earth.

[Erik Wright @digitalwright]

Congratulations to Aidan in our lab on the publication of his tool EvoWeaver: https://t.co/pOER0dT7V0

tl;dr Partial biochemical pathways derived from genome information alone.

[Erik Wright @digitalwright]

Protein structure search is becoming evermore popular. But I've always wondered whether some structure matches arise from convergent evolution. Now we know the answer – a resounding yes!
This has major implications for the use of protein structure search.
https://t.co/C4A04Qz1RQ

[Erik Wright @digitalwright]

Years of effort culminating into an excellent paper by Sam Blechman from our lab:

https://t.co/3ZHAYkPXGu

tl;dr MRSA infections are commonly treated with the antibiotic vancomycin. Yet MRSA almost never gains resistance. Now we known why vancomycin is so durable against MRSA.

[Erik Wright @digitalwright]

Congrats to Sam for his publication reviewing the intersection of EHR mining, machine learning, and antibiotic resistance! @JIDJournal

https://t.co/J6BNKpLwnX

[Erik Wright @digitalwright]

DECIPHER v3 released yesterday with lots of new features! Time to update: https://t.co/WVIxzWyjhb

[Erik Wright @digitalwright]

The Wright Lab has a new website! I think it's the coolest lab website ever, but don't trust me:
https://t.co/7Y5leX0VQ8
Many thanks to Monica in our lab for catching us up to 2024! 😎

[Erik Wright @digitalwright]

It turns out a lot of pseudogenes are actually genes. See our new publication in BMC Genomics. https://t.co/hCVoT1Vt31 The extent of this problem in public genome databases is mind blowing! Congratulations to Nick in our lab for figuring this out.

[Erik Wright @digitalwright]

Clusterize is now published in Nature Communications. https://t.co/4rSMhqd6Ji Clustering large numbers of sequences accurately in linear time via relatedness sorting. Check out the accuracy relative to MMseqs, CD-HIT, etc.!

[Erik Wright @digitalwright]

So proud of my lab for this new publication in a completely different area of research for us!
https://t.co/GGLpDMnqMr

And especially proud of this creative infographic created by our newest lab member!!
https://t.co/ybgzhoidAM

[Erik Wright @digitalwright]

Happy to see Travis' work in our lab out in print. An important read if you are doing #microbiome studies.

https://t.co/CrKpghmUce

[Erik Wright @digitalwright]

We need a plan D (for Data!)
https://t.co/Gw8B1hBuFq

[Seema_Lakdawala 🏳️‍🌈 @Lakdawala_Lab]

Excited this collaboration with @SCOTTeHENSLEY and Drew Weissman is out. Cool work in broad flu mRNA vaccines. Work on ferrets from my lab was done by @SageVle

[Erik Wright @digitalwright]

Clever method for getting rid of the thermocycler in PCR:
https://t.co/KYmLsl3YCn

[Akos T. Kovacs @EvolvedBiofilm]

Balancing Trade-Offs Imposed by Growth Media and Mass Spectrometry for Bacterial Exometabolomics
@AppEnvMicro from @digitalwright

https://t.co/jHiYcxEhed

https://t.co/jHiYcxEhed

[Erik Wright @digitalwright]

Very cool work on a conundrum in evolution: How to cross between fitness peaks? Many fitness landscapes have paths between peaks that circumvent valleys:
https://t.co/Qk2Tl0Zwta

[Erik Wright @digitalwright]

Congratulations to Jennifer Brennan for her new paper in @PLOSCompBiol

https://t.co/Nsijppp6Rg

In this collaboration with the @kgjamieson lab, we show how to easily find synergies among many drugs.

Synergies among combinations of up to 8 antibiotics were rare for 𝐸. 𝑐𝑜𝑙𝑖.

[Erik Wright @digitalwright]

@naturemethods More proof the 16S gene is insufficient for species level resolution:
https://t.co/V4WZVK4zyq

[Erik Wright @digitalwright]

Another day, another paper claiming to give species level resolution from the 16S gene, in @naturemethods:
https://t.co/L8MSLbE39D

See plot of correlation between 16S and genome divergence: https://t.co/BnYQXaELkI

Two bacteria with identical 16S can share 50% of their genes!

[Erik Wright @digitalwright]

🦇 Some moths have evolved to produce ultrasound capable of jamming bat sonar
https://t.co/4VZ1BxcL6J

[Olivier Elemento @ElementoLab]

This mind-blowing research in @Nature shows that machine learning can effectively guide enzyme optimization and help create enzymes that degrade all kinds of plastic waste in record time 🤯https://t.co/uGXX98EfKO