1st Place Match: JR Boys FS - 120 - Brayden Wenrich, PA over Michael Batista, NJ (TF 14-2 (2:06)) #Fargo2026
Wenrich wins Pennsylvania's first Junior title of the night and gives the state 53 all-time Junior golds.
๐OVER A CENTURY OF SCIENCE. ONE CONSISTENT MESSAGE.
โ๏ธIn medicine, few hypotheses have been tested as rigorously as the relationship between LDL cholesterol and atherosclerotic cardiovascular disease.
๐ 1913 โ Nikolai Anitschkow demonstrated that cholesterol-rich diets induce atherosclerosis in experimental models.
โค๏ธ 1948 โ The Framingham Heart Study established the association between cholesterol levels and cardiovascular risk.
๐ 1964 Nobel Prize โ Konrad Bloch and Feodor Lynen elucidated the biosynthesis and metabolism of cholesterol.
๐ 1985 Nobel Prize โ Michael Brown and Joseph Goldstein discovered the LDL receptor, transforming our understanding of cholesterol regulation and familial hypercholesterolemia.
๐ 1994 (4S Trial) โ Lowering LDL-C with statins reduced cardiovascular events and mortality.
๐+ ๐2015 (IMPROVE-IT) โ Further LDL-C reduction with ezetimibe translated into additional cardiovascular benefit.
๐2017โ2018 (FOURIER & ODYSSEY Outcomes) โ PCSK9 inhibitors demonstrated that achieving very low LDL-C levels produces further risk reduction.
๐งฌ๐ซ๐ป๐ฌ๐ฉปToday โ Genetics, epidemiology, pathology, imaging, Mendelian randomization studies, and randomized clinical trials continue to converge on the same conclusion.
More than a century of basic science and clinical research has consistently pointed in one direction:
๐LDL cholesterol is causal.
โ๏ธLower is better.
โ๏ธEarlier is better.
โ๏ธLonger is better.
When a scientific concept is supported by experimental biology, human genetics, epidemiology, randomized clinical trials, and two Nobel Prizes in Medicine, it is no longer merely a hypothesis.
๐ It is biology.
@society_eas@nationallipid
New in @AJPCardio:
Under the 2026 ACC/AHA dyslipidemia guideline, over 60% of U.S. adults aged 30-79 without ASCVD now have a statin indication, up from 43% under the 2018 guideline.
Thatโs 31.3 million newly eligible Americans.
But only 1 in 4 eligible adults are currently on therapy.
๐ https://t.co/d6NdxoZLzs
For those looking to say hello @nationallipid meeting in Chicago - I'll be there Saturday from mid-late morning till the evening ceremony - if travel goes well - Look for the oldest Lipidologist in the room! #NLASessions
๐ฃ๏ธ DUKE FANS HAVE SPOKEN
After collecting responses across Facebook, X, and Instagram for 48 hours, these were the players Duke fans said theyโre most excited to watch this season. ๐
One thing that stood out: fans mentioned nearly every player on the roster, showing just how much excitement there is for this team.
Who are YOU most excited to watch this coming season? ๐
#Duke #DukeBasketball #CBB
5โญ Duke commit Deron Rippey Jr. built his game on Brooklyn concrete and a family blueprint that left no room for shortcuts.
The nationโs #1 point guard is bringing his NYC tenacity to Durham, where heโs ready to cement his NBA dreams in reality. ๐
a study on rybelsus (oral semagltuide aka oral ozempic) showed that sema exposure was reduced by 40% when administered with 240ml of water vs 50ml, suggesting that drinking more than 120ml of water with the tablet would negatively impact absorption.
therefore, not only do patients need to totally restrict food before and after taking the tablet, but they must consciously prevent overdrinking water when taking the tablet.
this will inevitably lead to claims of "the tablet is not working for me" and you'll see churn due to lack of perceived weight loss efficacy.
every endocrinologist that has prescribed this drug in their T2DM clinic has reported the same thing.
Reminder! Please join us on Monday, April 27, 2026, from 9:30-10:30 am EST for Baim Grand Rounds with @ProfKausikRay, presenting โChanging the Paradigm of ASCVD Prevention.โ Zoom link: https://t.co/6uNNjfjytf
The American Heart Association mourns the passing of the legendary cardiologist Eugene Braunwald, M.D., widely recognized as one of the most influential figures in the history of cardiovascular medicine. Over seven decades, his work reshaped the understanding and treatment of heart disease, leading many to call him the father of modern cardiology.
Braunwald was a lifelong contributor to the American Heart Association, helping advance its research and scientific mission, and was honored with some of the Associationโs highest honors for his lasting influence on cardiovascular care and research. His influence extended well beyond his own discoveries, as generations of Associationโsupported investigators, clinicians and academic leaders were trained by Braunwald or guided by the clinical trial standards and mentorship models he helped establish.
https://t.co/ieZuHYMyOP
Congratulations @CBallantyneMD!! So well deserved! A true trailblazer and an incredible mentorโnot just to me, but to so many. Grateful to learn from you and to work alongside you! @vijay_nambi@BCMDeptMedicine
More on the amazing story of CETP inhibition with obicetrapib - was associated with attenuated decline in kidney function in patients at high CV risk: Post hoc pooled results from the BROADWAY and BROOKLYN trials https://t.co/lcFpI0Mo2e @nationallipid@society_eas@atherosociety@ASPCardio@escardio@NewAmsPharma
Duke fans are going to feel it from the jump.
With Deron Rippey Jr., itโs the pace, the burst, the confidence. The kind of guard who changes the energy the second he touches the ball.
Goosebumps every time he has itโฆyou ready for that?