Congratulations @CarolynBertozzi and @raflynn5 for the amazing discovery of glycosylated RNA, #glycoRNA.
Newly Discovered Glycosylated RNA Is All Over Cells: Study https://t.co/PeJM0rm3dI
Labcorp shares the data derived from #SARS_CoV_2 samples from patients with geographic and time metadata. After @PacBio sequencing 6,700 of these samples they were able to add mutation metadata showing the spread of variants. #SequenceEverything#HiFiDNA
https://t.co/8XZkG01XUg
What's the #HiFi advantage in viral sequencing? Fewer amplicon drop-outs, simpler amplicon balancing & the ability to call all mutation types robustly, even at low coverage. We're excited to bring this to bear on #COVID19 surveillance w/ a new protocol: https://t.co/7lkNMLgbLj
@Labcorp will be expanding their #SARSCoV2 sequencing with @Pacbio's Sequel II systems . The protocol, co-developed the two organizations, allows complete viral genome sequencing of 96-900 samples.
https://t.co/TljZrvEu8D
This study uses antibodies that bind to the Receptor Binding Domain (RBD) of the Spike protein preventing infection. Using a mixture of antibodies, some variants "escaped". Connecting the antibody pairs with a linker molecule prevents the mutant "escapes". https://t.co/DBhOzMEaCM
Th US has failed dismally in sequencing #SARSCoV2 samples from patients, from 0.02% to 2.6%, ranking 36th in the world. We are flying blind in a #pandemic. For comparison, Denmark has sequenced half of all its COVID cases. #SequenceEverything
https://t.co/dGEMw4tPBA
Francis deSouza, CEO of @illumina calls for a "Bio Force" to track the virus and declares "genomic surveillance is central to the solution. "
#SequenceEverything#COVIDsequencing
https://t.co/f1JGCpKKKL
Over 250,000 #SARSCoV2 genomes have been sequenced to date by the COG-UK consortium 🧬
A sombre, yet important milestone in the fight against the #COVID19 pandemic 😷
The history of the genome project was annotated with psychedelics. From Kerry Mullis' famed ride through the redwoods of northern California to Hilton Head's late night LSD beach party, a lot of the founders turned on. :-)
The 1st Psilocybe cubensis genome is now in NCBI.
This was sequenced with @PacBio HiFi and assembled with @infoecho Peregrine assembler.
It was annotated with FunAnnotate and RNA-Seq data from Whitehead/MIT (Torrens-Spence et al)
https://t.co/hQ7zXdUKy2
@SethOregon
@psilopedia
"these developments may lead to the democratisation of genome assembly projects which are now approachable by smaller labs with limited technical and financial resources."
#HiFiDNA#DNAdemocracy@PacBio
https://t.co/khEAmlHS6M