Here it is!!!😍
My first first author paper has just been released in the @JCellBiol
The majority of my PhD went into this work within the amazing NeuroCyto team and I couldn’t be prouder of the final outcome!
Congratulations to all involved 🎉
.@dombingham et al from @christlet's lab use bead-induced presynapses and CRISPR-tagging of endogenous #actin coupled to STORM to reveal distinct actin nanostructures within presynapses: a mesh at the active zone, rails, and perisynaptic corrals. https://t.co/vlN82jGZj8
@Dr_majio
A cell can change in seconds, and the important moment may be easy to miss.
RT-SuperES is working on microscopy that can spot those changes as they happen, then switch to super resolution for a closer look.
https://t.co/bpJENlSic0
#Microscopy#StemCells
Stunning STORM of intermediate filaments - excellent prep with the Smart Omnicell Kit on the SAFE platform by @abbelight.
Robust sample workflows like this help power real-time, high-content super-resolution in #RTSuperES.
#SMLM#STORM#Microscopy@EUeic#PathfinderOpen
Partner spotlight ✨: Prof. Geneviève Almouzni (@GAlmouzni)🔬 Pioneer of chromatin assembly & histone chaperones (CAF-1/HIRA). In RT-SuperES, she helps steer targets & live readouts—linking H3.1/H3.3 dynamics to real-time imaging ⏱️🧬 #RTSuperES#Chromatin@EUeic#PathfinderOpen
🔬 @christlet, @HenriquesLab, and colleagues introduce the Structural Repetition Detector (SreD), an unsupervised approach for identifying repetitive biological structures in #Fluorescence#Microscopy data.
🔗 Click to check it out: https://t.co/7BcIKpluU9
#Microscope#Imaging
🔬👨💻📰 #SReD is out!
Automated structural detection for #ImageJ & #FIJI, from nano to macro ✨🐘. No training data, no bias - texture analysis with GPU acceleration!⚡️ Brainchild of @afonsomendes92 and adventure w @christlet lab + friends.
Check: https://t.co/bkP94oAr7M
.@dombingham, @christlet et al. use bead-induced presynapses & CRISPR-tagging of endogenous #actin coupled to STORM to reveal distinct actin nanostructures within presynapse. https://t.co/vlN82jGZj8
From the Year in Cell Biology: https://t.co/2EJQw4PsR7
#Cellbio2023
.@dombingham, @christlet et al. use bead-induced presynapses & CRISPR-tagging of endogenous actin coupled to STORM to reveal distinct actin nanostructures within presynapses: https://t.co/vlN82jGZj8
In our Cellular Neurobiology collection https://t.co/qrQOQ6AseS
#SfN23
Congrats to @christlet and the Neuro Cyto Lab for having their image of the neuronal cytoskeleton featured on the cover of the Journal of Cell Biology! It was captured using a CSU-W1 SoRa system at our Center of Excellence in Marseille. Click for article: https://t.co/qGCAG3DGWc
.@JCellBiol's October cover shows a #neuron expressing endogenous GFP-#actin after CRISPR/Cas9-mediated tagging in a hippocampal neuronal culture labeled for MAP2. From @dombingham@christlet et al (https://t.co/RbMga3IWxb)
Read JCB’s October Issue: https://t.co/iRw0rZGqqH
Our October cover shows a #neuron expressing endogenous GFP-#actin after CRISPR/Cas9-mediated tagging in a hippocampal neuronal culture labeled for MAP2. From @dombingham@christlet et al (https://t.co/yoJfVBVOM0)
Read JCB’s October Issue: https://t.co/aPHG4tskvK
🚨New paper alert! @dombingham, @christlet et al. reveal distinct actin nanostructures in presynapses. Great work and congrats to all authors!
🔬A custom MASSIVE-TAG-Q-FAST ANTI-ALFA was used for 3D #DNAPAINT actin imaging.
https://t.co/0IGE9KbzxM
In @JCellBiol, @dombingham@christlet et al use bead-induced presynapses and CRISPR-tagging of endogenous #actin coupled to STORM to reveal distinct actin nanostructures within presynapses: a mesh at the active zone, rails, & perisynaptic corrals https://t.co/sW16TJxg6t
@Dr_majio
.@dombingham et al from @christlet's lab use bead-induced presynapses and CRISPR-tagging of endogenous #actin coupled to STORM to reveal distinct actin nanostructures within presynapses: a mesh at the active zone, rails, and perisynaptic corrals. https://t.co/vlN82jGZj8
@Dr_majio
To read Review Commons referee comments on @dombingham, @christlet et al's "Distinct nano-structures support a multifunctional role of actin at presynapses" #RefereedPreprint click on the second icon under the author line @biorxivpreprint