Dom Crocombe

[Dom Crocombe @domcro]

It's a huge honour to be attending the World Health Assembly at the @UN in Geneva this week.

Lots of incredible work going on here and around the world towards protecting our health.

Very cool stuff.

#WHA72 #UHC #climatechange #NCDs #globalhealth

[JAMA @JAMA_current]

Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting.

#CCR25 @CritCareReviews

https://t.co/GDpQJ68zpE

[BHFDataScience @BHFDataScience]

📣 A huge milestone for AI in healthcare, the BHF Data Science Centre has helped researchers to train an AI model on secure NHS data, aiming to:
📈 Predict patient health outcomes
🤝 Help with clinical decision-making
📄 Support NHS planning
🔗 https://t.co/Zgwqia9zNk

[Rui Castro @RuiCastroHD]

@meijnikman on the role of auto-brewery 🍺🦠 in SLD

The goal for the future is to use personalised medicine to eliminate high-ethanol-producing bacteria (gut microbiota transplantation, phages, antibiotics, pre|probiotics)

@EASLnews #SLDsummit @FrancqueSven @DebbieShawcros1

[Nature Medicine @NatureMedicine]

New Review from @FaiezZANNAD & colleagues calls for inclusion of patients with #MASLD and measurement of liver outcomes in cardio-kidney-metabolic trials, when data suggest benefits and safety. @ArunJSanyalVCU @JavedButler1
https://t.co/95WbFjtvUr

[Dom Crocombe @domcro]

@lisa_shark @FrontGastro_BMJ @PhilSmithIsBack @drfrancimoroni @GastroDrSmith Excellent!

[Charlie Lees @charlie_lees]

Diet may be the ultimate modifiable environmental factor to optimise human health and prevent / treat disease, including inflammatory bowel disease.

But it is not the only one

• Exercise and stress management also key
• Smoking and alcohol too

What would you add?

[Charlie Lees @charlie_lees]

I don't think diet is THE cause of IBD

But there is good epidemiological evidence now that the modern western diet is on factor contributing to the global rise in IBD. Some dietary factors may be drivers of inflammation rather than causative.

The role of dietary therapy in treating inflammation is established through exclusive enteral nutrition

Data for other dietary strategies is weaker.

A Mediterranean style diet is recommended if this is available locally and affordable.

A Mediterranean diet is typically prepared from fresh whole foods, minimally processed, with fruits, vegetables, leans meats, healthy fats and whole grains. Produce is typically season and local. Meals are enjoyed socially with family and friends. Physical activity and time in nature is also encouraged

IBD clearly a global problem arising across many cultures with a multitude of local cuisines. This gives us an opportunity to share knowledge and learn from each other.

For many people improving diet quality will have a profound impact on how they feel - including improved mood, sleep quality and energy levels.

Important additional considerations:

About 25% of IBD patients will also have a degree of IBS

Dietary fibre typically needs to be restricted in
• stricturing small bowel Crohn's disease
necessitates a low fibre diet
• during acute flares of colitis

[James Lee @Dr_James_Lee]

There's been amazing coverage of our new paper @Nature https://t.co/qkrUksBYVW but I wanted to put together a walk-through (and make this accessible as possible). It's a bit long so get a cup of tea! The full version is open access so pls do have a read if you are interested...

[Nutrition Doc @Leicnut]

Palliative parenteral nutrition and venting gastrostomy

'Both interventions improve quality of life but not without significant burdens.'

Inoperable malignant bowel obstruction: palliative interventions outcomes - mixed-methods systematic review https://t.co/Twgg0eddM8

[Seb @ibdseb]

📣📣📣📣📣💥💥💥💥

Truly transformational work by @Dr_James_Lee and @TheCrick team 👇
Macrophages driving IBD origin ; and perhaps also other autoimmune disorders

HUGE potential 👀

https://t.co/tGPCmcyRep

[Be Part of Research @NIHRtakepart]

Did you know that an online behavioural counselling tool with nurse support is effective at helping people lose weight? New research has shown this programme could be an effective and efficient way for the NHS to support people with obesity: https://t.co/NfyncMWUNz

[roypounder.apt @APandT]

Read open access "Branched-chain amino acid supplementation does not improve measures of sarcopenia in cirrhosis: results of a randomised controlled trial" at https://t.co/rMFQO7WNsJ
#livertwitter #cirrhosis #clinicaltrial

[Kohilan Gananandan @KGananandan]

Fantastic course at a wonderful institute! Some great insights and learning about this complex condition. Thanks to @HGronbaek and the rest of the faculty for great organisation and being so welcoming @konskaza @AUHdk

[NEJM @NEJM]

The editors announce a new series focusing on fundamental and emerging concepts in nutrition, from the “pharmacodynamics” of food to the gut and immunity and the role of the gut microbiome in health and disease. Read the full editorial: https://t.co/jTRjOrElyY

[NEJM @NEJM]

This week’s most viewed articles:

1. Original Article: A Cell-free DNA Blood-Based Test for Colorectal Cancer Screening https://t.co/n4wanKhie2 #Oncology

[PulseToday @pulsetoday]

NHS workforce plan relies on 'significant' substitution of qualified GPs, NAO warns https://t.co/X2g9Gd3PMB #longtermworkforceplan #NHSworkforceplan #NHSworkforce

[Gareth-Rhys Jones @Gastro_GRJ]

I’ve been working with the British Society for Immunology (BSI) to develop a new online training course on IBD immunology in clinical practice.

The first gastroenterology day is on 5th June;
details 👉https://t.co/767Kb8bPmG
@bsicongress @jimbrewer84 @PlevrisN @Bealoquebea

[David Nunan @dnunan79]

"It's going to protect YOU..."
"It will reduce YOUR risk of a heart attack, cancer, diabetes etc".

We see this all the time when it comes to medical treatments and health interventions.

I'm going to show why 99.9% of the time this type of phrasing/framing ("YOU/R") is wrong🧵

[richard horton @richardhorton1]

What have we done to medical students? https://t.co/YAhiS48czf

[Dom Crocombe @domcro]

@EileenBurns13 We’re all in this real world. It shouldn’t be an excuse to accept the status quo imposed on us.

I’m saddened that the thousands of eligible Drs denied UK training posts are not seen by Dr leaders as the primary solution.

Their barriers to entering workforce need lowering.