Check out this new @NatRevUrol#review from the lab of Dr. Robert Bristow at @CRUK_MI!
It shows how single-cell and spatial #transcriptomics are uncovering #ProstateCancer heterogeneity, evolution, and treatment resistance.
๐ https://t.co/QY0b40yaNm
๐ Proud to share our review in @NatRevUrol!
@jweischenfeldt#MigleMikutenaite#RobBristow
๐งฌ โSingle-cell and spatial RNA sequencing in prostate cancerโ
scRNA-seq and spatial transcriptomics are reshaping precision oncology in prostate cancer.
๐ https://t.co/UMLJIZG12o
Thank you everyone! ๐๐น
Archerthon 2025 wrapped up after 24 incredible hours. Weโve hit our target and raised over ยฃ5,500 for @RosemereCF
Huge thanks to everyone who donated, joined in or cheered us on. Every arrow counted ๐ฏ
Photos: https://t.co/Mbtt5vJNu8
#Archerthon2025
๐ฏ A truly Olympic prize!
Massive thanks to #BryonyPitman โ double Olympian & Team GB archer โ for donating her signed Paris 2024 shirt as a prize for #Archerthon2025 ๐น๐ฌ๐ง
๐ต๐กโซ๏ธ๐ข๐ด
๐ https://t.co/ifxQhDHa1o
Your support means the world ๐
Supporting @RosemereCF
๐ฏ Thank you, Linda Johnstone (@BigCButStillMe), for the beautiful handmade target cushion! So much love and care in every stitch โ truly a bullseye of perfection โค๏ธ
Check out her amazing work ๐
๐ https://t.co/Op4Vu9cwPw
๐งถ https://t.co/GwnYmb5ONQ
๐ฏ Thank you to the @BurnleyExpress for the fantastic coverage of #Archerthon2025!
The countdown continues - just 2 days!
@RosemereCF ๐
Read more here ๐ https://t.co/X0Gl4HyZHp
We have reached our ยฃ5,000 target! Thank you everyone for your support for @RosemereCF! The funds raised will surely make a difference for patients and their families.
#Archerthon2025
๐๏ธโโ๏ธ Weโre over the moon and under par thanks to @TheFlowerBowlEC ! โณ๐
Your ยฃ30 Crazy Golf voucher donation adds some fun to our #Archerthon2025 raffle and helps raise vital funds for the @RosemereCF, supporting patients across Lancashire and South Cumbria. ๐ฏ
๐ฏ Thank you to everyone supporting #Archerthon2025. Weโve reached the ยฃ2,500 mark! ๐ Just a few more weeks to go until the 24-hour archery challenge kicks off in aid of @RosemereCF ๐น๐ช
๐ Donate/Sign up: https://t.co/RNYhL9YDKy
Thank you Chris and Pete at #PurdieOak for donating ยฃ250 of luggage prizes to Archerthon 2025. Your generosity helps us raise funds for Rosemere Cancer Foundation. We really appreciate your support. Sign up or donate: https://t.co/RNYhL9YDKy #Archerthon2025@RosemereCF
๐ฏ 2 months to go!!
Join us for Archerthon 2025 - a 24-hour archery marathon in aid of @RosemereCF .
๐ https://t.co/VafO3oVqjS
25-26 Oct 2025 | Phoenix Archery, Burnley
#Archerthon2025#Rosemere
Metformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol
https://t.co/FpsOxB0bwU
In the STAMPEDE phase 3 trial, researchers evaluated whether adding metformin to standard of care could improve survival in non-diabetic patients with metastatic hormone-sensitive #ProstateCancer . Among 1,874 participants, no significant improvement in overall survival was observed with the addition of metformin (median OS: 67.4 vs. 61.8 months; HR 0.91, p=0.15). While metformin was associated with more gastrointestinal grade โฅ3 adverse events, it had an otherwise expected safety profile. Notably, metformin significantly reduced the adverse metabolic effects typically associated with androgen deprivation therapy.
These findings suggest that while metformin does not improve survival, it may offer metabolic benefits in this patient population.
@Silke_Gillessen@Prof_Nick_James@AshwinUrol@UroTaji@Hoda_Aty@DrAmandaAdler
Mohini Varughese @MPHRadiotherapy@AlisonBirtle
Mick Brown @MCRCnews@kittymisschan@scserendipity1
William Cross
David Dearnaley @ICR_London
Duncan Gilbert @ucl@EmilyGrist1@ArchieMacnair@minal_pm@fabioturco92
Patrick Williams @ProstateUK@mattsydes
Louise Brown @MRCCTU
@OncoAlert@AOmlin@nataliagandur@bavilima
๐น Huge congratulations to Mark & Raynor, our very own Archerthon committee members, crowned British Champions (Crossbow class) at the recent 3D Archery Championships in Nottingham 2025! ๐
Yet another reason to join the #Archerthon in aid of @RosemereCF! https://t.co/W0brTq9VXk
๐น Archerthon 2025 in Burnley
๐ 25โ26 October
๐ In aid of @RosemereCF
๐ฏ Take a tour of the battlefield
๐ฅ No experience? Join a taster session
๐ฏ Archer already? Book now as slots are limited
๐ Any donations welcome - every bit helps
#Archerthon2025
Most viewed this week from @JAMAOnc:
While phase 3 oncology trials frequently report success based on alternative endpoints, actual enhancements in overall survival and quality of life are uncommon.
https://t.co/4ZmqpzR6cQ
A huge thank you to #JollyTokki for sponsoring an hour of #Archerthon, our 24-hour archery fundraiser for @RosemereCF ๐ฏ๐น
This creative Sydney-based small biz adds a touch of flair and family spirit to handmade nail wraps ๐ ๐ฐ
๐ https://t.co/lj6bkwuYf9
๐ฏ Huge thanks to Phoenix Archery Burnley for being one of our main sponsors and ๐น hosting #Archerthon in support of this great cause.
Check out their shop ๐ https://t.co/Qv2RtGIqY5
@RosemereCF#CancerCare#Fundraiser ๐
Huge thanks to Oncology Consultants @ Rosemere for being our main sponsors and helping make #Archerthon a success. Your support is making a real difference.
Come down, show your support, and help us raise funds for vital #CancerCare!
@RosemereCF
A new @UroToday commentary builds on our meta-analysis of peripheral vs transition zone prostate cancer, examining outcomes and highlighting research gaps.
๐ง For those interested in prostate tumour zonal biology.
๐ https://t.co/BTvBYzUbDA...
@achoud72@BMJOncology