Prostate Cell News

An online resource for researchers studying prostate cells and prostate cancer. Part of the @STEMCELLTech Science News service.

[Prostate Cell News @ProstateCell]

GIVEAWAY! 🧡

Step into your lab in style with a pair of @STEMCELLTech science socks. 🧦

To qualify, subscribe to any of the 20 science newsletters offered by STEMCELL Science News and let us help you find your next journal club article. 📚

Learn more: https://t.co/ZePKd8T1eK

[Prostate Cell News @ProstateCell]

📢 New in @cddpress!

Scientists have identified a vulnerability in enzalutamide-resistant #ProstateCancer cells to ferroptosis and show that the arthritis drug auranofin may overcome resistance by targeting GPX4-dependent survival pathways.

Learn more: https://t.co/TEEvff5G6R

[Prostate Cell News @ProstateCell]

Gain- and loss-of-function studies in human #ProstateCancer cells and mouse neuroendocrine prostate cancer (NEPC) #organoids confirmed that sirtuin 1 promotes NEPC, while pharmacological inhibition suppresses it. 🧫

Read the full study: https://t.co/TG6hE8ak7i

🔓 #OpenAccess

[Prostate Cell News @ProstateCell]

Congratulations to @UTKnoxville's Dr. Kondapa Naidu Bobba, who has been selected to receive the 2026 Young Investigator Award. https://t.co/H13Fy9U8sz

Jointly supported by @PCFnews and @SNM_MI, this award will support Dr. Bobba’s research in radiopharmaceutical therapies to improve the outcomes for patients with metastatic #CRPC. 💊

[Prostate Cell News @ProstateCell]

This @oncogenejournal paper uncovers the significance of the ribosomal protein S15-DDX21-SCD1 axis in #ProstasteCancer development, expanding the understanding of noncanonical functions of ribosomal proteins.

🔎 Check it out: https://t.co/mUd4Rt681a

[Prostate Cell News @ProstateCell]

Clinical analysis revealed significantly increased pan-lactylated protein (Pan Kla) expression in #CRPC tissues compared to prostate cancer, accompanied by elevated lactate production and lactate dehydrogenase activity.

📚 Read the paper in @cddpress!

https://t.co/ftVQ0pY2e1

[Prostate Cell News @ProstateCell]

Using single-cell RNA sequencing of mice across pathological stages, scientists find an early neuroendocrine-initiating cluster marked by elevated HOXD11, conserved in human neuroendocrine #ProstateCancer.

Learn more: https://t.co/N65Zui8iGA

[Prostate Cell News @ProstateCell]

A new #review from the labs of Dr. @GertMeerleer and Steven Joniau (@joniau) at @UZLeuven explores how advances in imaging and metastasis-directed therapies are reshaping the management of oligometastatic #ProstateCancer, while highlighting ongoing challenges in defining and optimizing treatment strategies.

🗒️ Learn more in @NatRevUrol: https://t.co/z49QlPwrRL

[Prostate Cell News @ProstateCell]

📢 New in @MCT_AACR!

Researchers led by Dr. Allen Gao at @UCDavisUrology have identified IGFBP3-mediated SphK1/S1P signaling as a key driver of #enzalutamide resistance in advanced #ProstateCancer and a promising target for overcoming treatment resistance.

Learn more: https://t.co/mMYOZpVfiz

[Prostate Cell News @ProstateCell]

Congratulations to @fredhutch's Drs. Pallabi Mustafi and Ruben Raychaudhuri, who received Young Investigator Awards from the Prostate Cancer Foundation (@PCFnews)! 🤩

🗞️ https://t.co/XGpJGTpztR

Learn more about their work investigating #epigenetic features of aggressive #ProstateCancer.

[Prostate Cell News @ProstateCell]

🥼 Scientists at @PKU1898 synthesized a first-in-class, orally bioavailable, non-RGD pan-αv/α5β1 #Integrin antagonist, C19-9N.

🔗 https://t.co/7Vu72qFWhV

By co-targeting oncogenic drivers and #TME vulnerabilities, C19-9N heralds a transformative therapeutic paradigm with profound clinical potential for aggressive #ProstateCancer. 💊

[Prostate Cell News @ProstateCell]

This @jitcancer study, led by Huazhong University researchers is the first to map systemic immune dynamics after irreversible electroporation in #ProstateCancer using single-cell analysis.

📝 Read their findings: https://t.co/no9CBRQN4g

[Prostate Cell News @ProstateCell]

There are a number of studies that suggest the RAF-MEK-ERK-RSK cascade, a major #Oncogenic pathway, is activated in #ProstateCancer and this increases as the disease progresses. 🥼

Dr. @AdamSharpMedOnc and @ICR_London collaborators discuss. 🗣️

🔗 https://t.co/0iPbZbNo9O

[Prostate Cell News @ProstateCell]

New in @jitcancer!

Targeting LGALS9 enhances DC-mediated CD8+ T cell immunity and synergistically augments the therapeutic efficacy of tumor vaccines, representing a promising immunotherapeutic strategy for #ProstateCancer. 🎯

🔗 https://t.co/2NV2JFwqtR

[Prostate Cell News @ProstateCell]

The microbiome across the #prostate disease continuum. 🦠🪲

The authors propose a framework for the gut–urinary–prostatic axis and delineate when microbial and metabolite signaling meaningfully conditions prostate disease biology, and when it does not.

https://t.co/hKAg7062dK

[Prostate Cell News @ProstateCell]

A new study shows that ATM-deficient #ProstateCancer cells are highly sensitive to PARG inhibition, revealing a promising synthetic lethal therapy strategy for advanced prostate cancer. 🔬

Learn more: https://t.co/rd0HacocG2

[Prostate Cell News @ProstateCell]

📢 New in @oncogenejournal!

Researchers led by Dr. William Ricke at @UWMadPharmacy have shown that the RNA-binding protein DDX3X recognizes RNA G-quadruplex structures in #AndrogenReceptor (AR) mRNA to regulate AR signaling in treatment-resistant #ProstateCancer.

Learn more: https://t.co/hdCU2Y7p5X

[Prostate Cell News @ProstateCell]

A new study from the lab of Dr. Andrew Goldstein (@ASGoldstein6) at @UCLA demonstrates that OGDHL promotes #ProstateCancer growth and lineage plasticity by supporting nucleotide metabolism and is associated with neuroendocrine differentiation.

🗒️ Read the study: https://t.co/8Ik8djxScu

[Prostate Cell News @ProstateCell]

A new study led by Dr. K. C. Balaji at @UF_Urology suggests that newer MYC/MAX inhibitors more effectively suppress #ProstateCancer cell growth than earlier versions, supporting their potential as improved cancer therapies.

📄 Read the paper: https://t.co/FZRQVB8Ql6

[Prostate Cell News @ProstateCell]

New in @cddpress! 🤩

Nanchang University scientists reveal that the deubiquitinating enzyme USP13 is up-regulated in #prostate cancer (PCa) tissues and correlates with PCa progression.

👣 Follow the link: https://t.co/H4B0imN2nv