Short-term versus long-course neoadjuvant chemotherapy for resectable and borderline resectable pancreatic ductal adenocarcinoma (PACT-21 CASSANDRA): results from the second randomisation analysis of a randomised, open-label, 2 × 2 factorial phase 3 trial https://t.co/h4XwQHQ61D
#earlyonset#colorectalcancer with liver-only metastases
Leveraging real-world data from an Australian Cancer Database (TRACC) - differences in cancer biology, tumour location & treatment sequence on the overall survival of early- vs late-onset patients https://t.co/JYI4PdULU0
🧪 Serum CA19.9 in IPMN 🍇 to detect High-Grade Dysplasia and Invasive Carcinoma
🌎 Included in upcoming global GL!
🚨 In 4.6k pts CA19.9 POORLY 🙈 performed in excluding HGD / cancer
👎 No use as standalone / screening test!
🆓 @JAMANetworkOpen
https://t.co/gnTkj3JLfN
Postpancreatectomy diarrhoea 🔴🔴 an emerging issue in the era of pancreas cancer surgery
🚨Incidence 33% at 90 days
😖 Severity correlates with QoL
💊 PERT always required + 40% loperamide
✂️ Arterial divestment / vascular resection risk factors
https://t.co/i03eJ7lcQS
Oligometastatic pancreatic cancer 🔴 finally defined in @TheLancetOncol
🥇https://t.co/GEGfvnAy63
🧐 What about treatment?!
😉 Join our ongoing RCT SONAR 📡 https://t.co/TNVpQYDFv1
Additional resection of initially positive pancreatic neck margin was not found to be associated with oncologic benefits in postneoadjuvant pancreatoduodenectomy for PDAC. https://t.co/ruPzR1TKMa
New study from the DISPAIR consortium @BjsOpen!
Refined classification of postoperative pancreatic fistula after left pancreatectomy based on cumulative morbidity.
Open Access: https://t.co/WrnHwaFrhb
Hot from the press 🔥🔥🔥
"The @EAHPBA - @ESSOnews - Innsbruck consensus recommendations on peri- and postoperative management following liver resection" out now @hpbjournal. Happy to be able to contribute my small share in this!
https://t.co/iLHkjkGtrv
📝 Pretty cool data with the PUMP2 trial- HAIP for unresectable intrahepatic cholangiocarcinoma. @curecc@TheGutOncLab
48 patients. 22 patients (44%) achieved a PR and 42 patients (84%) disease control at 6 months. 5 patients (10%) converted to resection, of whom one had a pCR.
Median OS was 22.3 months (95% CI, 19.7 to 35.9 months). 1-year OS = 80.0% (95% CI, 69.6% to 91.9%), superior to the historical control of 47% (P < .001). 3-year OS = 31.5% (95% CI, 20.4% to 48.6%).
Definitely something I’ve been offering my patients if eligible. @WinshipAtEmory
https://t.co/dCjyqv8hVK
👽 Genetically engineered pig-to-human liver xenotransplantation !!!
🇨🇳 First successful auxiliary 🐖 liver xenotransplantation from 🧬 edited pig to a living recipient
no hyperacute or acute rejection… life saving bridge for liver failure ?! 🧐
https://t.co/k5XDlEcGhy
Dünyanın en önemli yayıncı kuruluşu olan Springer, Editörlüğünü ve Yazarlığını yaptığım Kist hidatik hastalığı konulu kitabımı yayınlamıştır. Ülkemiz ve İnönü üniversitesi adına hayırlara vesile olmasını dilerim.
What is your anticoagulation practice 💉 after portal vein resection in pancreas surgery ?!
🧑🧑🧒🧒 1k pts / 90 days thrombosis 7%
🔮 Predictors resection type / graft material
🩸 Therapeutic anticoagulation 📉 early thrombosis but 👎 at 90 days
https://t.co/16BWrpyt2Q
A positive resection margin does not determine long-term survival following colorectal liver metastasis resection
🌷https://t.co/8EgiB4rU0f
Ann Hepatobiliary Pancreat Surg 2025 Aug;29(3) Andreas Konstantinou
#Tumor_stage#Nodal_stage#Chemotherapy#Neoadjuvant
Prognostic factors for very early recurrence after neoadjuvant treatment and curative resection in pancreatic ductal adenocarcinoma @SurgJournal https://t.co/sGxdE6nIMq