Daniel Semblano

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Full Stack Developer

[Eron @0xEronn]

Without the Pauli Exclusion Principle, every electron in every atom would collapse to the lowest energy level. No chemistry. No molecules. No life. No hardware to run Claude on.

It's not a fundamental law — it's a consequence of wavefunctions being anti-symmetric. Two identical fermions in the same quantum state cancel each other out completely. Every GPU chip, every transistor, every bit of silicon that runs GPT exists because of this one sign flip.

19 minutes. Bookmark & watch today. The universe runs on antisymmetry.

[Breaking911 @Breaking911]

INSANE FOOTAGE: Russian troops mounted a YakB-12.7 helicopter machine gun on a fixed stand for training, but the exercise quickly went wrong.

[Daniel Semblano @dsemblano]

Not just knowing things. Not just being educated.
But being able to question your own assumptions, recognize your blind spots, and revise your thinking when new evidence appears.

[Daniel Semblano @dsemblano]

Metacognition is the ability to think about your own thoughts. It's one of the clearest signs of genuine intelligence. For us software developers, metacognition is the ability to debug the code in real-time.

[Daniel Semblano @dsemblano]

@TrueSlazac For me, living in northern Brazil (where guaraná comes from), this is the best guaraná soda, hands down.

[All day Astronomy @forallcurious]

🚨: Speed up footage of Artemis II mission re-entry and splash down in the Pacific Ocean!

[The Best @TheBestqueenx]

Dozens of fishermen end up losing body parts to wolf fish.
This is because many people don't realize that even after being "dead" and without a body, it is still capable of this.

[Curiosity @MAstronomers]

Artemis II mission route in 3D

[Akhilesh Mishra @livingdevops]

No disrespect to Linus Torvalds, But Ken Thompson might be the biggest geek who ever lived. 🫡

And almost nobody knows his name.

At 28, he created Unix.
> The OS that inspired every modern operating system on the planet.

At 66, the age when most engineers retire, he co-created Go.
> A language millions of developers love, and used to build most of modern Devops tools like Kubernetes, Terraform, Prometheus, Grafana, etc.

But that is still not the full story.
- Dennis Ritchie built on Thompson’s B to create C.
- Linus built Linux inspired by Thompson’s Unix.
- He co-invented UTF-8, the encoding behind every website you visit.
- He built grep, a tool developers still use daily in 2024.

The internet you are scrolling right now exists because of him. And he did everything without Claude, cursor, ChatGPT.

Ken Thompson. Remember the name.

[Restoring Your Faith in Humanity @HumanityChad]

Strangers see hateful note on her back... quietly remove it so she never sees the words. “It’s just a joke” - they shield her heart.

This is protective kindness at its purest. ❤️

[Restoring Your Faith in Humanity @HumanityChad]

He called his stepmom "Mom" for the first time in so many years. 🥺

[Jason R. Williams, MD, DABR @jasonwilliamsmd]

This isn't my field. But the principle is everything I believe about medicine. The body was designed to regenerate. Give it the right environment and it will.

There is no approved treatment on earth that restores motor function after a complete spinal cord injury. A team led by Dr. Tatiana Coelho de Sampaio at @UFRJ in Brazil may be changing that.

They spent 25+ years developing polylaminin, a stabilized polymer of laminin. Laminin is a protein your body uses to build neural connections during embryonic development. After birth, it becomes scarce. They figured out how to recreate it in the lab.

One injection directly into the injured spinal cord. It acts as a biological scaffold. Axons regrow across the injury. Glial scarring is reduced. Neurons reconnect.

Their pilot study included 8 patients with complete spinal cord injuries. Two died from the severity of their trauma. The 6 who survived? All of them regained voluntary motor control. Normally only about 15% of these patients recover any motor function on their own.

In 2025 they tested it on chronically paralyzed dogs. Dogs that hadn't recovered after months of physiotherapy showed significant gait improvement.

ANVISA approved Phase 1 human trials on January 5, 2026. But patients couldn't wait. Brazilian courts have been ordering compassionate use access because the regulatory timeline can't match the biological urgency.

250,000 to 500,000 people suffer spinal cord injuries every year worldwide. For most of them, nothing exists that restores what they lost.

The body knows how to heal. Sometimes it just needs the right scaffold. Now watch how long the system takes to let everyone else have it.

[Restoring Your Faith in Humanity @HumanityChad]

Meet the story of Ryan Catterson, a delivery driver who, in 2020, in Rhode Island (USA), was going through the most difficult moment of his life: he had recently lost his teenage daughter. 💔

During a routine delivery, something extraordinary happened: a two-year-old boy named Cohen ran up and gave him a surprise hug, unaware of the grief Ryan was carrying.

This innocent gesture deeply touched the heart of the suffering man. ❤️‍🩹

A powerful reminder that, even in the darkest moments, empathy and unexpected kindness can bring a light of hope.

[Restoring Your Faith in Humanity @HumanityChad]

50 Cent gets emotional as he meets a girl from an orphanage he saved through his donations 🥺❤️

When 15-year-old Maya posted a simple video about how 50 Cent’s words helped her push through the hardest days at school, she never imagined he would actually see it. But he did.

And when he learned she’d been carrying far more than her share - juggling classes, a job, and raising her younger siblings - he stepped in without hesitation or spotlight. 👏

He covered her school expenses. He found her a tutor. He gave her the room to breathe, to dream, to just be a kid again.

With that support, Maya didn’t just finish school – she graduated with honors. 🥲🎓

And when she walked across that stage, 50 Cent whispered the words she’ll never forget: “You did the work. I just helped you believe you could get there.”

This moment right here, when they first came face-to-face, was incredibly-powerful. ❤️

[Jason R. Williams, MD, DABR @jasonwilliamsmd]

We've spent 50 years trying to kill cancer cells. What if the answer was never to kill them but to remind them who they are?

Cancer cells aren't foreign invaders. They're your own cells that lost their identity. They stopped differentiating, stopped maturing, and started growing without limits. Cancer doesn't create anything new. It hijacks normal biology.

Researchers at KAIST in South Korea identified three master regulators, MYB, HDAC2, and FOXA2, keeping colon cancer cells locked in a malignant state. When they silenced all three? The cancer cells differentiated back into normal, healthy tissue. MYC and WNT pathways shut down. In mice, tumors shrank significantly.

No chemo. No radiation. Just reprogramming.

Here's what most people will miss: HDAC2 is a histone deacetylase. It compacts DNA and silences tumor suppressor genes. We already use HDAC inhibitors in our protocols. This isn't new to us. But it's powerful validation.

Cancer and aging are the same problem. Cells that no longer serve the body but learned to hijack the immune system to survive. The answer isn't bigger bombs. It's restoration.

Still preclinical. But the direction is exactly right. Kudos to the @kaistpr team. 👏

[Curiosity @MAstronomers]

708 GB image of the Moon 🌑

[Wonder of Science @wonderofscience]

The LI-900 silica tiles used on the Space Shuttle were such poor heat conductors you could grab them with bare hands seconds after pulling them from a 2200 degree oven.

[Seán Ono Lennon @seanonolennon]

New @cl_delirium drop! (This is the intro to our upcoming epic-techno-psychedelic-rock-opera!)

https://t.co/ky9KTROrfu

[tiway🦋💙 @sitiwayyy]

That’s how mattress density works. Which one would you choose? 🛌

[Tobi Mülhauser 🍕 @iamtobi]

Why aren't parking lots drawn like this everywhere?