Dan Spakowicz

Assistant prof at The Ohio State studying the microbiome & cancer

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔬 New in J Immunother Cancer by Dr. @dspakowicz.
#Tumor_infiltrating #microbes are emerging as key players in #TNBC therapy response. Check it out! https://t.co/4XJ2AcnLVU
@OhioStateMedOnc @OhioStatePIIO

[Ohio State Medical Oncology @OhioStateMedOnc]

📝New publication from @dspakowicz & colleagues in @jitcancer: Tumor-infiltrating microbes and therapy response: a new frontier in triple-negative breast cancer precision oncology https://t.co/QSbtE5QoAm

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔬 We're looking forward to the next #PIIO Research in Progress Seminar
“#Candida_albicans infiltrates #tumors causing radiation resistance and decreased survival”
🗓 Friday, Jan 23, 2026
⏰ 10:00 AM
📍 BRT 115
🎙 Presenter: Dennis Grencewicz III (@SciBehindSciPod)
🧠 Mentor: @dspakowicz

[Ohio State Medical Oncology @OhioStateMedOnc]

📝New publication from Ning Jin, @SciBehindSciPod, @dspakowicz & colleagues in @CRC_AACR: Epigenetic Modulation, Intra-tumoral Microbiome and Immunity in Early Onset Colorectal Cancer #exorienconsortium #microbiome
https://t.co/3FrYukFph5

[Nature Methods @naturemethods]

In another Perspective @QinMaBMBL, @dspakowicz and team explore the debate surrounding the role of the tumor microbiota and discuss strategies that might help answer these questions.

https://t.co/H6WJ5jOc8h

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🎉 Congrats to @QinMaBMBL, @dspakowicz & team on their new @naturemethods Perspective!

This exciting paper lays out evidence, pitfalls & next steps for studying the #tumor #microbiome.
Check it out!🔗 https://t.co/zzf0Z6Z0hP @OSUCCC_James @OSUWexMed

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🚨 New study finds that early acute kidney injury (AKI) during #pembrolizumab‐based treatment in metastatic #NSCLC is linked to worse 12-month survival.
Close monitoring & preventive strategies are key.
📄 Early AKI & Survival in Front‐Line #Immunotherapy
https://t.co/53YP5GV5sY

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Join us for the Pelotonia Institute for Immuno-Oncology Research-in-Progress!
📅 Friday, April 25 | 🕙 10 AM | 📍 EAIC 130
🧬 "The tumor microbiome affects the microenvironment as a function of the microbe and cancer type"
Presented by @OhioStateMedOnc, #PIIO researcher Dr. @dspakowicz.

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

@OSUCCC_JAMES, #PIIO researcher, Dr. @dspakowicz, is discussing how lifestyle-based modifications of the #microbiome can improve #cancer treatment outcomes—linking diet, microbes, and #immunotherapy response. #Host_Microbe in the Digestive Tract Symposium.

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🚨New publication from a research team that includes @OhioStateMedOnc, #PIIO researcher Dr. @dspakowicz on #GutMicrobiome, #immune shifts, & #MentalHealth during an immersive psychosocial intervention. Findings reveal links between Prevotella-dominant #microbiome & #depression resilience. 🧠🦠 Read more: https://t.co/IZRgV3H5Ah

[Journal of Geriatric Oncology @JGeriOnc]

Resiliency among older adults receiving lung cancer treatment (ROAR-LCT): A novel supportive care intervention for older adults with advanced lung cancer https://t.co/UtsyTqlI4a @CPresGeriOncMD @dspakowicz @e_paskett @WilliamDale_MD @rochgerionc @myCARG #GeriOnc #OlderAdults

[Ohio State Medical Oncology @OhioStateMedOnc]

📝New publication from @CPresGeriOncMD, David Carbone, @dspakowicz, @e_paskett & colleagues: Resiliency among older adults receiving lung cancer treatment (ROAR-LCT): a novel supportive care intervention for older adults with advanced lung cancer https://t.co/KCwt6pyHin

[Cell Host & Microbe @cellhostmicrobe]

From poo to promise: Fecal microbiota transplants support immunotherapy resensitization in solid tumors
@LAURAJMOULTON @SciBehindSciPod @dspakowicz highlight work showing FMT improves anti-PD-1 inhibitor efficacy in unresectable or metastatic solid cancers https://t.co/ZJOEmAkQkW

[Ohio State Medical Oncology @OhioStateMedOnc]

📝New publication from @dspakowicz, @SciBehindSciPod & Laura Chambers: From poo to promise: Fecal microbiota transplants support immunotherapy re-sensitization in solid tumors
https://t.co/TtiEf3GcS8

[Waggoner Lab @LabWaggoner]

From poo to promise: Fecal microbiota transplants support immunotherapy re-sensitization in solid tumors
@dspakowicz @cellhostmicrobe @LAURAJMOULTON
https://t.co/W30Pkh7Cl8

[Cancer Research Communications @CRC_AACR]

#ICYMI: The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors, by Caroline E. Dravillas et al.
https://t.co/VpPTyAagSh
@dspakowicz @ATarhiniMDPhD @OhioStateMedOnc @OSUCCC_James @MoffittNews #openaccess

[Ivan Zanoni @Lo_Zanzi]

#WeekendRead! #MicrobiotaPower! @dspakowicz @willahsueh &co show @NatureComms that microbiota from obese individuals drives accumulation of neutrophils in the fat of high fat diet fed mice, causing loss of Tregs & increased Th1 inflammatory lymphocytes! https://t.co/pzpsf2SEqM

[Waggoner Lab @LabWaggoner]

Obesity-associated microbiomes instigate visceral adipose tissue inflammation by recruitment of distinct neutrophils @willahsueh @dspakowicz
https://t.co/MrlEJimlid

[Dan Spakowicz @dspakowicz]

@OhioStateMedOnc @OhioStateMed Strong work, @SciBehindSciPod!

[Ohio State Medical Oncology @OhioStateMedOnc]

Dennis Grencewicz, @OhioStateMed student and AOA fellow working with @dspakowicz, presented research on gavage with Candida albicans leading to fungal colonization of colorectal tumors and decreased response to radiotherapy at #AACR24