Dimitrios Tsallos

PhD candidate @FIMM_UH, excited to work in translational research for drug development, member @team_icombine. Globetrotter, infinitely curious.

[Peter Tennant has moved to Bluesky @PWGTennant]

Good data analysis is tricky. It requires knowledge, training, & thought. That's not gatekeeping, it's a fact for most scientific tasks!

Machine learning tools may be tempting, but naive data-driven analyses can be dangerously misleading. We need more thought not less.

[Peter Tennant has moved to Bluesky @PWGTennant]

"We should be afraid. Not of intelligent machines. But of machines making decisions that they do not have the intelligence to make. I am far more afraid of machine stupidity than of machine intelligence" - @MelMitchell1

[c0nc0rdance @c0nc0rdance]

In 2018, "Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial" was published in the British Medical Journal.

It sought to determine if wearing a parachute when jumping from a plane had any impact on survivability.

It did not.

[Darrion Nguyen @lab_shenanigans]

when you’re in the middle of an experiment and halfway you realize you’re out of a reagent

[David Juurlink @DavidJuurlink]

Next time you hear someone say "tHe sHoTs r KiLliNg peOpLe!" remind them which group is actually dying

https://t.co/zE6uiTDG6c

[Kjetil Tasken @KjetilTasken]

Great to be at the Functional #PrecisionMedicine for #BloodCancer Workshop and Symposium. Exciting yesterday on FPM and drug screening to stratify patients to therapy. Now Day2 and @DrTonyLetai speaking on what we have to do to prime cancer cells to therapy! @TheSFPM @kporkka

[Dimitrios Tsallos @dtsallos]

Great start of the second day at #FunctionalPrecisionMedicine for blood cancer symposium with focus on immunotherapy. Nice to see so much great work produced in transatlantic collaborations. @TheSFPM

[Olli Dufva @ollidufva]

Our work using single-cell and genome-scale CRISPR functional genomics to study the interaction of NK cells and blood cancer cells now out on bioRxiv: https://t.co/L9asxtKqy6

Close collaboration with co-first author @DrSGandalf and @CMitsiadesLab @hruh_research

🧵

1/

[Dimitrios Tsallos @dtsallos]

Great session at #FunctionalPrecisionMedicine for blood cancer workshop showing a lot about ex vivo assays and clinical trials. Very clear benefit using the assays on VenEx trial, great work by @LabKontro

[Journal of Experimental Medicine @JExpMed]

New pre-clinical study uncovers a therapeutically actionable molecular mechanism of #azacitidine mediated thrombocytopenia in #MDS #AML by Okoye-Okafor et al. @The_Will_Lab @Einsteinmed @Einstein_SCI: https://t.co/bSv6lcaHpF

@dsallos @Amitvermamds @aditishasMD
#Leukemia

[Britta Will @The_Will_Lab]

Very excited to see this online! Many thanks to project lead, Dr. Cynthia Okoye-Okafor, our fantastic collaborators, and @JExpMed for a smooth publishing process.

[Elli Papaemmanuil, PhD @PapaemmanuilLab]

Are physicians ready to adopt clinical decision support tools to interpret molecular profiling data?

2 months since publication (https://t.co/l6yIjCyeH9), the IPSS-M calculator (https://t.co/YCZG3yy7o6) has computed risk for 17,640K MDS patient profiles from >60 countries.

[Stephen Semler @stephensemler]

The amount Elon Musk just paid for Twitter ($44 billion) is nearly equal to Biden’s proposed climate budget ($44.9 billion), in case anyone's wondering how seriously we’re taking the climate crisis

[Oscar Brück @oscarbruck]

Welcome to join our team! We value also applications from researchers not pursuing master's or PhD degrees. Feel free to share. #ComputerVision #MachineLearning #DeepLearning #leusm #BigData

[Oscar Brück @oscarbruck]

Hello world! I’m happy to present you the Hematoscope Lab
https://t.co/mGivxhEECZ

[David Juurlink @DavidJuurlink]

"Omicron's milder so why get vaccinated now?"

Omicron:

[Theodore Lytras @TheodoreLytras]

Άρθρο μας με @STsiodras στο @JournalSjph για θνητότητα 🇬🇷 διασωληνωμένων #COVID19 ασθενών σε σχέση με το φόρτο του συστήματος υγείας, ως αρχές Μαϊου 2020.
https://t.co/XcRrXbxhRO
Αναδεικνύει τις χαμηλές "αντοχές" του ΕΣΥ, που δεν αφορούν μόνο τη διαθεσιμότητα ΜΕΘ. *Thread*

[Kontro Lab @LabKontro]

Ex vivo drug sensitivity testing predicts venetoclax+azacitidine treatment responses in AML. VenEx trial interim results presented at #ASH21

[Olli Dufva @ollidufva]

Excellent talk by @hkuusanm on predicting response to venetoclax+azacitidine in AML using ex vivo drug screening #ASH21

[Deirdre Gilhawley @DeeGilhawley]

New study on role of primary school children in transmission⬇️

▪️Genetic sequencing done on all positive cases

▪️Most household transmission "originated from within the school"

▪️"Children may play a larger role in the transmission of SARS-CoV-2 than previously assumed" [1/3]

[Nature News & Views @NatureNV]

A machine-learning algorithm has been used to optimise the allocation of COVID tests at the Greek border. Read more in this excellent N&V by Ziad Obermeyer @oziadias
https://t.co/yQ7jnbjuI7