durocherlab

We are located at the Lunenfeld-Tanenbaum Research Institute and work on understanding the fascinating processes underlying genome integrity

[durocherlab @durocherlab]

Incredible stuff from Tiger in Pelletier lab

[Tiger Jian @tigerhzjian]

(1/6): How can we better test therapeutics without using animals or risking lives? Lab-grown human mini-organs, called “organoids”, provide an answer! Despite their progress, organoids and related methods lack realistic flow through blood vessels, the “plumbing” of our bodies.

[durocherlab @durocherlab]

@FGH_Lab @SEBBM_es @ibis_sevilla @InvestigaUS Congrats Fernando!

[Artem Babaian @RNA_Life]

Molecular Genetics @ University of Toronto 🇨🇦@UofT🦠 is recruiting an Assistant Professor in #Virology!!

Come build your dream lab!

🔗https://t.co/MMq1l7y1PA

[Premier ministre du Canada @PMcanadien]

Ce jour nous rappelle solennellement les graves conséquences de la violence fondée sur le sexe. En mémoire des 14 jeunes femmes assassinées à Polytechnique Montréal, réaffirmons notre devoir de combattre cette violence et d’associer le souvenir à l’action. https://t.co/jDl4uB2e44

[Ernst Schmid @ernstschmidd]

Thrilled to share that the final piece of my PhD work is now on bioRxiv! https://t.co/uS3S3epIHR With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at https://t.co/X3pDRrLPj9

[durocherlab @durocherlab]

@Arnab_RC1 Congrats Arnab! Very cool story!

[Dan Landau @landau_lab]

Big, beautiful trees!!

SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life.
https://t.co/pciw5yME0x

[durocherlab @durocherlab]

@jjonkers2 @luijsterburglab @keith_caldecott 😆

[durocherlab @durocherlab]

Kaima Tsukuda and Andy Blackford have a highly complementary study that indicates that mutations in DDIAS (and CIP2A) caused neurodevelopmental defects, pointing a role for this pathway in development. /fin

https://t.co/1IzP6sZBeQ

[durocherlab @durocherlab]

New work from the lab! 🔬 We report that DDIAS is a new component of the mitotic CIP2A-TOPBP1 pathway of genome maintenance.

https://t.co/oXoTdFwqO4

[durocherlab @durocherlab]

Longer thread on the Blue site.
Thanks to all authors and collaborators, chiefly
Yibo Xue but that's not all!

[Sinai Health @SinaiHealth]

Job Alert 🚨
We are looking for outstanding candidates to join our institute!
Find out more & apply:
Biomedical Discovery ➡️ https://t.co/HOjgJmHio7
Population Health Data Science ➡️ https://t.co/qBl4JkKXcf

[durocherlab @durocherlab]

@Hiom_Lab Kevin, wishing you many adventures in retirement!!!

[durocherlab @durocherlab]

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
https://t.co/pNPOg1u3ZB

Please repost!

[Fusion Conferences @Fusion_Conf]

⚠️DEADLINE APPROACHING ⚠️

#BGFP25 early bird and talk submission deadline closes on 30 Jan 2025! 🧬

Don't miss out on the opportunity to present at this fantastic conference, submit your abstract now ➡️ https://t.co/SPvZHEY0vB

[NatureRevClinOncol @NatRevClinOncol]

In a Review now available online, Natalie Ngoi, David Gallo, Carlos Torrado, Mirella Nardo, Daniel Durocher & Tim Yap provide an updated and comprehensive overview of the role of systhetic lethal strategies in cancer therapy https://t.co/Yx76Qvts6F

[Tycho Mevissen @TychoMevissen]

Excited that our work on transcription-coupled DNA repair is now published @CellCellPress! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples stalled Pol II to TFIIH. 🧬🐸

➡️ https://t.co/0SDr81nzhu

[Cell @CellCellPress]

Now online! Pervasive mislocalization of pathogenic coding variants underlying human disorders https://t.co/lcUaMg35JO

[Miguel Ramalho-Santos Lab @MRSantosLab]

Postdoc positions in the @MRSantosLab! Please RT. Upcoming departure of several very successful lab members + new funding = postdoc positions! Exciting new avenues in mouse development, hypertranscription, dormancy and environment-epigenome interactions.
https://t.co/1vyyptbUSb

[durocherlab @durocherlab]

Great start of the Durocher lab retreat. Some of the entries to our lab meme effort! You may notice a theme....