Elizabeth Chun

Computational biologist | Research Associate in Park Lab @HarvardDBMI | Bioinformatics & Cancer Genomics | PhD @UBC @BCCancer_GSC, Marra Lab Alum

[Elizabeth Chun @echun77]

What an honour of a lifetime - Huge congratulations to my PhD advisor, Marco! @mmarra0630

[Michael Smith Labs @ubcmsl]

It is with heartfelt congratulations that we share that Dr. Marco Marra has been appointed an Officer of the Order of Canada.

Dr. Marra is recognized for how he “propelled Canada to the forefront of genome research.”

Learn more: https://t.co/rd9nYuQyjf

[Peter J Park @peter_j_park]

Mutational signature analysis has become a key tool for interpreting somatic mutations. Our tool MuSiCal (Mutational Signature Calculator) by the amazing Hu Jin (@hujin2hujin2) and Doga Gulhan (@dcgulhan) is out at Nat Genetics: https://t.co/8Cy6dWmhPa. Three key ideas below.

[Teng Gao @tGaoTeng]

Aneuploidy is a defining feature of cancer cells, but is it also present in healthy normal tissues? In our paper out today on @NatureGenet, we report hundreds of mosaic chromosomal alterations (mCAs) found in diverse tissues from #GTEx. A thread (1/7)
https://t.co/JtzP7d1oRL

[Dominik Glodzik @dominikglodzik]

Chromoscope is now published in @NatureMethods!

Chromoscope is open-source and well-documented. Try it out on example/your data and share your feedback!

@sehi_lyi @peter_j_park @ngehlenborg @trevmanz @chromoscope_bio
#CancerGenomics

[Cancer Discovery @CD_AACR]

Read this week's #ResearchWatch:
Estrogen-Induced Translocations Precede Amplification in #BreastCancer, a summary of the paper by @jakelee0711, @peter_j_park et al.
https://t.co/hNAZ6MNc2y
@harvardmed

[Elizabeth Chun @echun77]

@jakelee0711 @Nature Many congratulations, Jake! I am so impressed by your dedication and tenacity to decipher these complex rearrangement events to arrive at the causal mechanism. Congratulations again! 👏👏👏

[Jake June-Koo Lee @jakelee0711]

1/
We are excited to share our new story about how oncogenes are amplified in breast cancer genomes and the role of estrogen in igniting this process through genomic rearrangements. The story came out in @Nature today, and here is the thread!
https://t.co/wTARjKuVPH

[NIH Common Fund @NIH_CommonFund]

Following #FAIRData principles, our #SMaHTNetwork's Data Analysis Center will help #BiomedicalResearchers easily find and reuse #SomaticMosaicism data that can help catalyze discoveries in human #biology and #disease. Learn more: https://t.co/QNLjGLWxck

[Peter J Park @peter_j_park]

We are delighted to be the Data Analysis Center for this new NIH Common Fund effort!

NIH launches $140 million effort to investigate genetic variation in normal human cells and tissues https://t.co/51tbWtMnYZ

[Elizabeth Chun @echun77]

Congratulations, elim @LimEmilia ! 😀👏👏👏

[Charles Swanton @CharlesSwanton]

Today our important study on air pollutants in the promotion of lung cancer has been published in @Nature led by @WillHilliam @LimEmilia @DrClareWeeden @SwantonLab ...Thread below🧵https://t.co/q1ICykmVox

[Peter J Park @peter_j_park]

Here is a story of how @jinkukkim found an antisense oligonucleotide (ASO) that can up-regulate a key protein in a neurodegenerative disease. Joint work between my lab and @timyu. 1/n https://t.co/18QumKBju7

[Elizabeth Chun @echun77]

👏👏👏 Congratulations, Sally! @sarperotto

[UBC Science @ubcscience]

Congratulations to evolutionary biologist & @ZoolgyUBC prof Dr. Sarah Otto (@sarperotto) on winning a #KillamPrize2023.

@nrc_cnrc #UBC

https://t.co/ffOz4X5G9J

[Peter J Park @peter_j_park]

Trying to catching up on social activities after the pandemic, the Park lab headed to Florida for a lab retreat!

[AGBT - Advances in Genome Biology and Technology @agbt]

Abstract Select: @peter_j_park from @harvardmed focusing on single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements at the 2023 @AGBT General Meeting. #AGBT23

[Elizabeth Chun @echun77]

👏👏👏

[Yuka Takemon, PhD (竹門ゆか) @YukaTakemon]

I'm super honoured to make it into one of @ATJCagan's amazing illustrations! Thank you!

[Elizabeth Chun @echun77]

👏👏👏

[Harvard University @Harvard]

Claudine Gay has been elected the 30th president of Harvard University https://t.co/NH86VoTLit

[Peter J Park @peter_j_park]

Can we identify single nucleotide variants and indels accurately at the single cell level? Joe Luquette developed SCAN2 to examine >50 neurons and finds enrichment of indels at brain-specific enhancers/promoters. Collab with @ChrisAWalsh1
lab. Full text: https://t.co/jFIT1vkThE

[Doga Gulhan @dcgulhan]

I am thrilled that our work on predicting PARPi response in breast and ovarian cancers using mutational signatures from panel data is out at @CCR_AACR! Collaborating with @felipe_batalini and Gerburg Wulf was great, and many thanks to @peter_j_park!
👇
https://t.co/phHWIQP19f

[Yuka Takemon, PhD (竹門ゆか) @YukaTakemon]

Interested in mining #GeneticInteraction and #CoEssential networks from #DepMap? Try out GRETA! It's a simple-to-use R package with options to customize your queries based on mutations, cancer context, and much more.
https://t.co/xTfNdZCMsl

[Elizabeth Chun @echun77]

When the Golden Eye was opened... 😍😍😍

[NASA @NASA]

It's here–the deepest, sharpest infrared view of the universe to date: Webb's First Deep Field.

Previewed by @POTUS on July 11, it shows galaxies once invisible to us. The full set of @NASAWebb's first full-color images & data will be revealed July 12: https://t.co/63zxpNDi4I