Edward Hoefer

[hbd chick @hbdchick]

comedian Jimmy Carr on the importance of the church having banned cousin marriage in the middle ages.

now THAT'S my kinda stand-up routine! 😂👍 h/t @edwest

[Chloe @Chloe71207]

Husband Reaction when seen the strip...........

[Mario Nawfal @MarioNawfal]

😂 Something I didn’t expect to see today:

Cows are really good swimmers and in Ireland, farmers load them onto boats to take them to graze on offshore islands.

Who knew? Irish cows are living their best lives.

[Edward Hoefer @edhoefer]

@LibertyCappy Listen to her and egg her on to greater heights until she tells you you're going too far. Let her run half an hour then "Hey honey, we could move to another country, or maybe we should consider extreme, not so legal actions to get back at her for what she said about your hair."

[Pendragon Foundation @PendragonOrg]

Castles are our heritage in stone.

[Give A Shit About Nature @giveashitnature]

If you're worried about ticks, put up an owl box.

The animal driving most Lyme disease in the eastern US is the white-footed mouse. Ticks that feed on them are far more likely to come away infected than ticks that feed on other animals. The bigger the local mouse population, the worse the next year's tick year.

A single barred owl pair raising chicks can take hundreds of rodents in a breeding season. Owls also don't carry Lyme. The bacterium can't survive their digestive tract, so an owl that eats an infected mouse is a dead end for the disease.

Researchers at the Cary Institute, the leading lab on Lyme ecology, have been explicit about this: "Landscapes that support predators have reduced Lyme disease risk."

One owl box on its own isn't going to fix a tick year. But a yard with owls, foxes, bobcats, and weasels in it has fewer mice, and a yard with fewer mice has fewer infected ticks.

If you have woods or fields nearby, a properly sized barn owl or screech owl box (different species, different boxes) is one of the most useful single things you can do for tick exposure at the landscape scale. Match the box to the owl that lives near you.

The mouse is the problem, owls are the solution.

[Healthy Alfred 🏄🏻‍♀️ @HealthyAlfred]

BPC-157 fixed injuries that doctors called permanent.

Severed nerves — REGREW.
Torn ligaments — REBUILT.
Destroyed gut lining — REVERSED.
A punctured cornea — HEALED.
Parkinson’s tremors — GONE.

Not in years. In WEEKS.

→ regrew SEVERED nerves
→ reattached tendons to BONE
→ 90% knee pain relief in HUMANS
→ reversed gut damage from Advil
→ healed a PUNCTURED eye
→ reversed Parkinson’s and prevented DEATH
→ no lethal dose EVER found

A 15-amino-acid peptide from your own stomach juice. Your body makes it. Just not enough to finish the job.

That shoulder. That knee. That gut. Every injury you still carry is a repair your body started and never completed.

500+ published studies. Your doctor has never mentioned it.

BPC-157 finishes what your body quit on.

I take Barrier Health’s oral tablet BPC-157 personally. No injection. No prescription. Code ALFRED saves you 15%. I’ll drop the link below.

[Mario Nawfal @MarioNawfal]

🇮🇹 An Italian studio just built a robot that carves marble statues with millimeter precision.

Michelangelo's David took years. These machines finish complex sculptures in 11 to 15 days.

[Nature & Animals🌴 @naturelife_ok]

Damn, this is peak bird intelligence.

These birds saw someone feeding a wounded bird, so they started pretending they were also injured.

[Give A Shit About Nature @giveashitnature]

Farmers have figured out that the cheapest pesticide is a strip of flowers.

When you plant wildflowers through a crop field, not just around the edge but in strips running through the middle, you get ladybugs, lacewings, hoverflies, and parasitic wasps living in the field instead of visiting it.

They eat the aphids, the caterpillars, and the mites for free, all summer long.

In controlled trials, fields with tailored flower strips had leaf-beetle numbers 40 to 50% lower and crop damage cut by around 60%, enough to drop below the threshold where spraying was even considered worth it.

The flowers attract a standing army to our fields.

We spent decades engineering chemicals to kill the insects eating the crop, when the insects that eat those insects would have worked for the price of seed.

[Colossal Biosciences® @colossal]

We built an artificial egg and hatched chicks.

The Colossal artificial egg has a bioengineered shell designed to breathe like a real egg. And because a South Island giant moa egg was ~80x larger than a chicken’s, this will be critical tech for bird de-extinction.

[Muse @xmuse_]

One of the most shockingly underrated masterpieces of the Renaissance is Anthonis Mor’s portrait of Sir Thomas Gresham (c. 1560), now in the Rijksmuseum in Amsterdam.

When people see it today, especially in high-resolution pics, they often mistake it for a 19th-century photograph or even a hyper-realistic AI generation.

The skin texture, the eyes, the subtle sheen on the black fabric, make it feel almost disturbingly modern.

Yet this painting, created over 460 years ago, barely registers in the mainstream conversation about great art.

It deserves far more recognition.

[Massimo @Rainmaker1973]

The Netherlands has become the first country in the world to successfully eliminate stray dogs, ensuring that every dog has a home.

This remarkable achievement stems from a combination of strict animal welfare laws, large-scale spaying and neutering programs, and a strong culture of responsible pet ownership. The Dutch government has long supported widespread sterilization initiatives and enforces tough penalties for animal abuse and abandonment.

While an estimated 200 million stray dogs exist worldwide, the Netherlands stands out as a global leader. In Dutch cities, it is common to see dogs riding in bicycle baskets, relaxing under café tables, and even joining their owners on public transport, a reflection of how deeply integrated pets are into everyday life.

The country now serves as an inspiring model for animal welfare, demonstrating how coordinated policy, cultural awareness, and compassion can effectively solve a challenge that continues to affect many other nations.

[Massimo @Rainmaker1973]

Alzheimer’s may be linked to gum bacteria, new research shows.

Scientists have repeatedly found Porphyromonas gingivalis—the chief bacterium that causes periodontitis—inside the brains of people who died with Alzheimer’s.

When researchers deliberately infected mice with this oral bacterium, the animals rapidly developed key Alzheimer’s pathology, including the buildup of amyloid-beta plaques.

Perhaps most alarming, the bacteria’s toxic enzymes have been detected in the brains of people showing early Alzheimer’s changes years before memory loss or other symptoms appear, suggesting the infection may quietly initiate damage long in advance.

These discoveries have sparked serious interest in new treatment approaches. An experimental drug called COR388 (from the company Cortexyme) has already succeeded in lowering both bacterial load and amyloid-beta levels in preclinical models. Although large human trials are still needed, the evidence is mounting that at least some cases of Alzheimer’s may have an infectious trigger rather than being purely degenerative.

[Dominy, S. S., et al. "Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors", Science Advances, 5(1), eaau3333]

[Edward Hoefer @edhoefer]

X You are here. X

[Yun-Ta Tsai @yunta_tsai]

Attempted to write a Steam Engine hype at the era of Industrial Revolution as if it was the age of AI —

The steam engine breakthrough is insane right now.

Watt’s separate condenser + new GRPO optimization just dropped the 405 hp-class engine. We went from 7 hp → 70 hp → 405 hp+ in basically three years. One machine now does the work of 50+ men or water wheels — nonstop, rain or shine, anywhere.

Textile mills, ironworks, everything scaling 5-10x overnight. Productivity exploding.

This isn’t incremental. It’s automating physical labor at massive scale. Jobs shifting forever. Society about to look unrecognizable.

The Industrial Revolution isn’t coming. It’s here and accelerating faster than anyone predicted.

Terrified. Excited. Both.
What a time to be alive. 🚂💨

[Critically Thinking & Drinking 🧐 🥃🧉🍸🍹🤪 @TheCriticalDri1]

Stay with it 😂😂😂😂

[Saffron Sniper @Saffron_Sniper1]

These two giant turtles have been fighting each other for more than 120 years.

According to the zoo, one turtle stole the other’s food 120 years ago, and since that day they became enemies.

There hasn’t been a single day where they don’t fight for 2–3 minutes😂

[Megan Gafford @megan_gafford]

I was recently awarded a New Aesthetics grant from @patrickc and @tylercowen to try to invent a new ornamental style of architecture.
I’m going to do this through drawing, because just as writing is thinking, drawing is imagining. You might invent something new when you sit down to solve the problem of what your version of a thing should look like.
Link to my full project description below 👇

[David Sacks @DavidSacks]

Back-of-envelope numbers for 1 gigawatt data center:

All-in Capex: ~$50 bn
Enterprise revenue generated: ~$25-30 bn/year
Electricity cost: $1-2 bn/year

~2 year payback.

The boom is real.