Elliot Hui

Scientist and educator

[Chroma Medicine @chromamedicine]

New data presented today at #AHA23 show that a single administration of our #PCSK9 epigenetic editor therapeutic durably lowered cholesterol levels in vivo.

Read more: https://t.co/QW7hsU2dFG

#EpigeneticEditing #Biotech

[Elliot Hui @elliothui]

This turned out beautifully! Congrats, @RonZhu2015 @P32jm and the rest of the team.

[ElowitzLab @ElowitzLab]

Two decades ago @AvigdorEldar & @BarkaiLab introduced concept of shuttling, in which protein circuits push morphogens away from their source, or smush them into narrower regions. We have now reconstituted shuttling in mammalian cell culture: https://t.co/mlQPLULGGS.

[Elliot Hui @elliothui]

Whaaaat is this!?!?!! 🤑 No more grant writing!

[CNN International @cnni]

A minuscule handbag measuring just 657 by 222 by 700 microns (or less than 0.03 inches wide) sold for over $63,000 at an online auction https://t.co/jtqChLXFOw

[Elliot Hui @elliothui]

@Droplet_guy @fordycelab @cidar_lab Thanks for the thoughtful replies, Ali. For the Matrigel, it’s complex enough that we generally just go for trial and error, which works well enough for now. Very nice work here!

[Elliot Hui @elliothui]

@Droplet_guy @fordycelab @cidar_lab Beyond simply size, can we address questions of stability and even biocompatibility?

[Elliot Hui @elliothui]

@Droplet_guy @fordycelab @cidar_lab What would it take to extend this work to predict behavior for viscous, non-linear fluids such as Matrigel?

[Elliot Hui @elliothui]

@Droplet_guy @fordycelab @cidar_lab And now that HFE 7500 is being discontinued, can such a tool be used to predict the behavior of replacement reagents?

[Elliot Hui @elliothui]

Very proud of @SeeAvash and our work on programmable pneumatic computers. Published today and featured in New Scientist. https://t.co/rq1ZTSRKM4

https://t.co/dtFyB0C909

https://t.co/opOzPOdq55

[Chroma Medicine @chromamedicine]

Thrilled to be presenting groundbreaking data today at #ASGCT23 demonstrating the power of harnessing an endogenous system to regulate gene expression. Check out this thread to learn how we did it. 🧵
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#EpigeneticEditing #Tweetorial

[Will Ratcliff @wc_ratcliff]

I’m delighted that our paper on the Multicellularity Long Term Evolution Experiment (MuLTEE) has, at long last, been published. This paper establishes the foundations of what I’d like to work on for the rest of my career. 1/25

Free, full access link: https://t.co/lWh33eHQrf

[Institute for Protein Design @UWproteindesign]

01. Today we report the computational design of highly efficient enzymes. Lab testing confirms that these novel luciferases can recognize specific synthetic substrates and efficiently catalyze the emission of light.

https://t.co/IeGKoGhc2g

[Elliot Hui @elliothui]

@fordycelab Congratulations, Polly! Time to celebrate and soak it in.

[Niko McCarty. @NikoMcCarty]

🖭🖭 A Brief History of Parafilm 🖭🖭

"Cling wrap on steroids." "Duct tape of science." "The forbidden lab cheese." Parafilm has many names.

But what is this stuff? Where did it come from? And can you actually eat it? 🧵

https://t.co/ba1s9v89mE

[Elliot Hui @elliothui]

Thank you! Have been looking for something like this for a while.

[Seth Bannon @sethbannon]

Introducing the Spinout Playbook, a free guide to spinning a startup out of academia.

https://t.co/tIs74dn4e8

Why is this needed? The process of “spinning out” science from universities is broken 👇🧵

[Zoran Nenadic @zoran_nenadic]

This piece of news was worth waiting for! Ronke's @OlabisiLab 2022 @BMESociety Diversity Lecture is finally up: https://t.co/evxNQJoaxp

Very comprehensive and highly informative!

Olabisi Presents 2022 Biomedical Engineering Society Diversity Lecture https://t.co/O5cdAZV3nz

[Transon Nguyen @transonn]

After a year of building in stealth, I’m really excited today to announce the launch of Eigen Therapeutics! At @EigenTx, we develop “priming therapies” that modulate target expression levels on cancer cells, making them easier to find and eliminate.

https://t.co/HJ3gKqyhsW

[Jim Brody @jpbrody]

Kamran Ali and Transon Nguyen, former UCI BME (@elliothui lab) students, started Eigen Therapeutics & just raised a $7 million seed round
Eigen's developing a highthroughput platform to discover priming therapies. This should enhance existing targeted therapies for cancers.

[Ons M'Saad @OnsMSaad1]

***See your cells without a microscope*** 👀
Introducing #UnclearingMicroscopy, where cells are expanded 8,000 volumetrically and opaqued with light-scattering molecules of high density to reveal cell microstructure with the naked eye
bioRxiv: https://t.co/owAt3oS5Rc

[Brian Cummings @DrBrianCummings]

Tenure Track position for someone broadly focused on stem cells and tissue engineering to join strong collaborative environment at UC Irvine. Applications due by Jan 6th 2023. #tenturetrack #stemcell #UCI #facultyjob https://t.co/BqUAybXcS4

[Elliot Hui @elliothui]

@ampenner Really excellent work, Andrew! I’m impressed by the size of your data set, but perhaps that is par for the course in your discipline. Might it be possible to obtain similar data for specific fields? Of course I’m personally interested in bioengineering, especially academia.