JCI - Complement-producing maternal microchimeric cells override infection susceptibility in complement-deficient murine offspring https://t.co/KBwDRNTUsE another example for what microchimeric cells can do, in this case offset disease severity associated with missing proteins
Our latest #EmerginLeaderinMI is Theresa Alenghat @AlenghatLab. Read her review on "Epithelial regulation of microbiota-immune cell dynamics" online now: https://t.co/sUrNxSyfvL
Excited to share my first 1st author paper! A review on how the epithelium regulates the dynamics between the #microbiota and immune cells. Thanks to @emeshlem and the @AlenghatLab for helping me throughout this process! @MucosalImmunol@CincyImmunology https://t.co/t1spmNvo5K
Featured on our latest episode: The @AlenghatLab found that #butyrate controls tuft cell dynamics through histone deacetylase 3.
Learn more about the connection with #Type2Immunity in the @ImmunityCP paper: https://t.co/e0Gem2milz
Listen to the episode: https://t.co/pgVXIxXq99
Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity: Immunity https://t.co/wBhYRbDLtP Thrilled to see work by amazing colleagues @AlenghatLab@emeshlem published in Immunity
#MicrobiotaPower! @AlenghatLab &co show @ImmunityCP that microbiota-derived butyrate inhibits HDAC3 in intestinal stem cells, preventing excessive tufts cell differentiation, thus calibrating type 2 immunity in the intestine! https://t.co/KXO8fBuHKr
Pleased to share our new study @ImmunityCP led by Dr. Emily Eshleman @emeshlem on tuft cell regulation in the intestine. Many thanks to our wonderful collaborators on this project! https://t.co/VB8iQZVD5x
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity. Congrats @emeshlem on your recent paper in @jclinicalinvest! @babiesresearch https://t.co/enfkuWLHna