Want to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal : https://t.co/YmsR18WcRJ
The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity - Simonsen - New Phytologist - Wiley Online Library https://t.co/9IAzHfc7y1
Francis Collins resigned from NIH yesterday. He rightly pointed out that it's Human Genome Project revolutionized every aspect of biomedical research. He points out that NIH has historically been sens as high priority and non partisan.
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The Trump administration's efforts to slash research funding have US graduate students, postdocs and other early-career scientists fearing for their careers. Some are considering changing jobs or leaving the country. Others say them might abandon research altogether.
https://t.co/9afome3UzX
Happy to share our latest discovery of the autoactive CNGC15, sufficient to enhance root endosymbiosis in legume and field grown wheat: https://t.co/hjPLOxrIQI
Thank you to everyone involved! Special shout-out @NicMCook1, G.Gobbato, collaborators
@DaveLawson101 , @CristobalUauy
Excited to share our latest work on faba bean-rhizobium interactions https://t.co/e52LrriMNg headed by @marcemendoza at @MolBiolAU . A joint @ProFaba_SusCrop and @N2CROP_AU effort highlighting rhizobium diversity and its impact on plant growth.
Glad to share our new cryo-ET work
https://t.co/nB7RzQn1vo
I resolved ribosomes to sub-3 Å in cells, realizing the potential we demonstrated. In PTC core where our interested drug Chloramphenicol binds, the local res. hit 2.7 Å, enabling deciphering its MOAs in atomic details.
Hibernating ribosomes have a complex social life in starved yeast cells: they assemble into intricate clusters and bind to mitochondria, illustrating how ribosomes hibernate in their natural habitat. More—in this fascinating study by @jomaa_lab: https://t.co/wDSEkPPmRk
Did you know that nuclear pore complexes can turn up outside the nuclear envelope? Studying these, @JennySachweh, Bernhard Hampoelz and others uncover that the surrounding cellular milieu determines NPC composition via the nuclear transport system itself. #teamtomo#NPC A 🧵
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Happy to share our little discovery with @SimoneMattei19 team on how ribosomes hibernate upside down on mitochondria during cellular stress is now out @NatureComms! A collaboration between @medicineUVA, @EMBL, @EmblImaging, MEMC. Congrats to all authors! https://t.co/DE6eAamt5I
I will move to National University of Singapore. Several research assistant, PhD, and postdoc positions are open. I'm interested in nitrogen fixation under changing climates! Please contact me if you are interested! I will attend #ICBPI in Hangzhou. Come and talk to me!
I will move to National University of Singapore next April. There are several PhD and postdoc positions open (closest PhD deadline is 15 Nov 2024). You are welcome to apply. It will be great if you can RT. Look forward to the next chapter.
We have a new paper for you: “Structure of tetrameric forms of the serotonin-gated 5-HT3A receptor ion channel”.
Here we found that the prototypical pentameric ligand gated ion channel can form stable tetramers and characterized it with cryo-EM/ET and molecular simulations.