Nigel Delaney

[𝕐 @nomad421]

Did @10xGenomics just make newer versions of Cell Ranger open source? https://t.co/5aGEEN9dL8 (cc @sjackman, @luizirber). This is a huge win for open, transparent, and reproducible science if it’s the case!

[10x Genomics @10xGenomics]

Help us shape the future of data analysis. Take this survey, sharing your experiences using Cell Ranger, Space Ranger & Cloud Analysis to analyze single cell or spatial datasets. The first 100 eligible respondents will get a pair of 10x Genomics socks! https://t.co/H9SVccUIv6

[Nigel Delaney @evolvedmicrobe]

Does anyone know someone who works at the Genomic Data Commons at NIH? Looking for someone I can ask about a recent data sharing policy there.

[Rahul Satija @satijalab]

We’re excited to release a Seurat update with support for Spatial Transcriptomics data! Includes clustering, interactive visualization, and integration with scRNA-seq references. Check out our vignette on @10xGenomics Visium data: https://t.co/jWPypTHvvi

[Emily Delaney @ipaemily]

Check out this super fly Christmas gift from @evolvedmicrobe! Beats our previous "Maita Honda" frame.

[Nigel Delaney @evolvedmicrobe]

@lopantano @lopantano by default Cell Ranger only uses 16 GB for the ALIGN_READS stage, someone had to manually set it to 220 GB and so override the default when they ran mkref. The 64 GB you found also seems too high, the _jobinfo file can help you refine that estimate.

[Nigel Delaney @evolvedmicrobe]

@RepGaramendi The NRDC wants you to support the SAVE Right Whales Act, where do you stand on this issue?

[PacBio @PacBio]

It's here! We’re thrilled to announce the launch of the Sequel II System, reducing project costs & timelines with approximately eight times the data output compared to the previous Sequel System. Look at that beauty! 1/3

[Nigel Delaney @evolvedmicrobe]

Received a bogus debt collection notice from a company that knows it would cost me more fighting it than paying it. @AGBecerra's office just put them on notice that parasites aren't welcome in California. #GovernmentWorking #CommonProblemsCommonSolutions

[Nigel Delaney @evolvedmicrobe]

@10xgenomics has an opening to help develop and lead the single cell revolution. If you’re smart, capable and have a desire to doing something impactful, send me a line! https://t.co/1CisJWujsc

[Spatial Transcriptomics - Part of 10x Genomics @STomics]

Today we announced the acquisition of our company by @10xgenomics and are excited to have our novel technology for spatially-resolved transcriptomics join their best-in-class product portfolio. https://t.co/PR529gUHCo

[Nigel Delaney @evolvedmicrobe]

@infoecho I may follow your lead and write that up sometime! Rewriting CCS to have an order of magnitude better accuracy while using 1/5th the input data remains a highlight of my career.

[Nigel Delaney @evolvedmicrobe]

Old job went from a cutting edge science start-up to $1.2B acquisition. Don't know how to guarantee that outcome, but know you're guaranteed not to get it without uniquely brilliant coworkers who are emotionally invested. @infoecho was one of those: https://t.co/fFn5H95ybI

[Graham Coop @Graham_Coop]

Re. Elizabeth Warren. A plot of the probability of inheriting exactly 5 blocks of your genome from a specific ancestor (as a function of # generations back to that ancestor). Details here: https://t.co/B3zL1K6J53

[Nigel Delaney @evolvedmicrobe]

Just came from the crowd @MikeReissWriter left in stitches. I knew why he had 4 Emmys, and after in person confirming his talent now know why he doesn’t have 10 (hint: his wife lacks the “Ex” prefix). If you liked the Simpsons, buy this book: https://t.co/ZPjdYQyIL3

[Johannes Köster (@johanneskoester.bsky.social) @johanneskoester]

I am happy to announce Rust-HTSlib 0.21 and Rust-Bio 0.22. Rust-HTSlib contains many small usability improvements (a lot of them implemented by @10xgenomics). Rust-Bio provides a comprehensive HMM implementation (thanks to Manuel Holtgrewe). Great work by a growing community!

[Graham Coop @Graham_Coop]

Interesting, @ucdavis has just introduced preprints category on the faculty merits/promotion file system. Nice way of moving things forward.

[Nigel Delaney @evolvedmicrobe]

Very happy to have been interviewed by the wonderful @biodids for the GSA blog! https://t.co/2TFh8mTE5M

[Graham Coop @Graham_Coop]

Folk asked about inbreeding. Here's sim. (1000 inds/deme) zoomed in, total & unique ancs in dark & lighter cols respectively. Genealogical ancs soon overlap, genetic ans still lag

[Nigel Delaney @evolvedmicrobe]

If @RepJeffDenham votes again for this tax bill I am going to make sure he isn't elected again. Higher taxes for Californians, no elimination of the AMT or carried interest deduction, and increased debt? Selling out your district will have consequences. #SimplerNotHigherTaxes