FCWEI

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[Jason Locasale @LocasaleLab]

Real science is slow, uncertain, and humbling. It thrives on doubt, failure, revision, and debate.

Universities, funders, and journals want the opposite: speed, certainty, confidence, and narrative.

So we get bad models, fake breakthroughs, and flashy press releases. And everyone pretends it’s progress.

[Cell Metabolism @Cell_Metabolism]

New! Online now: A famsin-glucagon axis mediates glucose homeostasis https://t.co/GIAy8xYsbO

[Nature Aging @NatureAging]

Online now! @FCWEI2 et al. show that supplementing folic acid during methionine restriction in flies mitigates the decline in fertility while retaining the intervention’s life-extending benefits. @LocasaleLab (https://t.co/uRSF0zn041)
https://t.co/XxCcHz7nSn

[FCWEI @FCWEI2]

@LocasaleLab @NatureAging Thank you, Jason. I appreciate your help and guidance. Thanks also to the lab members for assistance.

[Jason Locasale @LocasaleLab]

Our study now published @NatureAging - we show that the tradeoff between lifespan extension and reduced reproduction can be uncoupled by modifying die. We considered methionine restriction as example. Congrats @FCWEI2 and everyone else who helped 🎉.

https://t.co/F0E9hyuFWh

[Nature Metabolism @NatMetabolism]

Online now! Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans https://t.co/rgRDrlG2ca

[Jason Locasale @LocasaleLab]

Our latest preprint led by @FCWEI2 - organismal lifespan extension is shown to be separable from reproduction limitations in the context of dietary methionine. We further investigate the underlying metabolism of the phenomenon.
https://t.co/R3xwAePqPU

[Immunity @ImmunityCP]

Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis https://t.co/StX3prNW8n

[Anirban Maitra @Aiims1742]

This month’s imaginative @Cancer_Cell cover:
The Monkey King (NK cells) recognizes & tries to kill the White Bone Demon (CTCs), who is disguised as a girl. However, the White Bone Demon pretends to be innocent & convinces Tripitaka (platelets) & Pigsy (HLA-E) to protect it.

[The Innovation | Medicine @Innov_Medicine]

Very creative way of studying anatomy

[Satchin Panda @SatchinPanda]

We will not see the real data in this #TRE paper. Because #NEJM allowed the authors not share any data. Terrible data sharing policy at #NEJM.
https://t.co/8sAE44vO7P

[Cell Metabolism @Cell_Metabolism]

How do dietary glucose and fat signal to the brain to alter feeding behavior? Revisit this exciting paper from @AmberAlhadeff's Lab to find out!
#gutbrainaxis #diet #macros #CellMet1YearAgo #OpenAccess @MonellSc

[Cell Metabolism @Cell_Metabolism]

Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction https://t.co/SjxYwyYBtc

[Cell Metabolism @Cell_Metabolism]

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist https://t.co/1Q2cJ7sdDu

[Cell Metabolism @Cell_Metabolism]

NEW ISSUE!: Featuring work from Vila et al. discovering that STING regulates polyunsaturated fatty acid (PUFA) metabolism, and in turn, PUFAs inhibit STING-dependent inflammation.
https://t.co/d6exB5BDGd

[Satchin Panda @SatchinPanda]

A chemical from grape seeds can reduce senescent cells and increase healthy lifespan in mice.
https://t.co/PgM85t1ffK

[Satchin Panda @SatchinPanda]

I am grateful to my research team and colleagues ⁦@salkinstitute⁩, my collaborators throughout the world, scientists and clinicians who have been rigorously testing the the power of an optimum circadian rhythm in fighting #diabetes. #circadiandiabetescode on sale now.

[Cell Metabolism @Cell_Metabolism]

Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape https://t.co/3udd5B6W04

[FCWEI @FCWEI2]

Fructose help a tyrant to victimize his subjects. https://t.co/bwtBA0kmxx null