Felicia Basilicata

Group Leader at @UnimedizinMainz | @ginsosagelab Res. Associate. Chromatin, rare diseases and organelle networks. Opinions expressed here are solely my own

[Molecular Cell @MolecularCell]

Online Now: A time-resolved atlas of histone modifications during mitotic entry https://t.co/CrbHvqSNfk

[Tugce Aktas @_taktas_]

Our most recent work on the “function and evolution” of #nuclear_speckles is now online at Cell @CellCellPress
https://t.co/8QvEbVcofu
Read the thread 👇for the highlights of our findings.

[Hao Yin @HaoYin20]

Transposable Elements LTR7 as mechano-responsive enhancer elements

Matrix stiffness (40 vs 1 kPa)▶️
YAP/TEAD1-BRD4-CTCF▶️
LTR7 (FAM-LTR7)▶️
FAM189A2▶️
⏬definitive endoderm differentiation hESC

352 TE subfamilies changed by Stiffness🤠

Among "238 LTR7 loci coregulated by both matrix stiffness & YAP, 59 regulated by stiffness alone and 8 by YAP alone"

@YaruiDiao @NatureCellBio 2025
https://t.co/4hvmBlOabv

[LifeScienceAlliance @LSAjournal]

KANSL3 controls hepatocyte differentiation and metabolism via histone acetylation. Loss of this epigenetic regulator leads to hyperplasia and liver fibrosis. #Epigenetics #Metabolism #Hepatology #NSLComplex @AsifaAkhtar1 @mpi_ie https://t.co/kGQBqzLMqk

[Max Planck Society @maxplanckpress]

Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️https://t.co/kz0macEMTX - Please share the Open Call among potential candidates.

[Zuzana Storchova @ZStorchova]

Just out! Aneuploidy alters cellular proteome and affects many functions. One protein, p62/ SQSTM1, becomes highly abundant and creates cytosolic bodies in cells with extra chromosomes.
https://t.co/4TGS1MltUy

[Daniel Andergassen @DAndergassen]

We are so happy to be on the cover @sarahhoelzl @amycaoart 🎉 The cover depicts the Three Fates, who manipulate the threads of life and death. The Fates are shown as three older women, unraveling the threads of the inactive X chromosome during aging. https://t.co/dP4Er7B4d6

[RaffaellaSantoroLab @LabSantoro]

Very excited to share our latest work in @MolecularCell showing NPM1 stabilizing the association of nucleolus associated domains (NADs) and recruiting G9a to establish their repressive chromatin states. https://t.co/3JLKZ04eYx

[Bedzhov lab / Embryonic Self-Organization @emselor]

Step-by-step protocol for induction, maintenance, and exit from embryo dormancy in mice
https://t.co/nES0Jk2GQ0

Congrats to Rui Chen and Rui Fan!

[Jan Żylicz @JZylicz]

Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. https://t.co/5Ms6tNyT5l @NatureCellBio

[Felicia Basilicata @Feli_Bas]

@JZylicz @NatureCellBio Beautiful work. Congratulations to the all team

[Felicia Basilicata @Feli_Bas]

Excited to be part of Freddie& Co's fascinating work! Who knew "Sea-Monkeys," a child's first pet for many, would reveal such cool insights about sex chromosome regulation and aging differences? A treat for fans of evo-devo and non-model organisms! #ScienceCollaboration #Genomics

[Claudia 🕊 Keller Valsecchi @KellerValsecchi]

🚨Happy to share our newest work from fabulous PhD student Frederic - he was brave enough to add a new species to our #zoo 🦀 enjoy what Crustacean #sexchromosomes and #H4K16ac teach us about #epigenome evolution and #ageing https://t.co/sGF0LiIeny

[Nature Metabolism @NatMetabolism]

✨New issue! ✨

Check out the latest in #metabolism research from across all disciplines.

Read about #Macrophages, #Tcells, #Circadian biology, the effects of #Diet on #Body and #Brain - and many more topics!

https://t.co/JKcHxpyhZv

[Felicia Basilicata @Feli_Bas]

Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals: Cell Stem Cell https://t.co/bb6ldXVN22

[Daniel Andergassen @DAndergassen]

I am super proud to share the first Andergassen Lab preprint! Here, we introduce a new framework to decode the non-coding genome, led by the outstanding work of @HasenbeinT and co-authors @sarahhoelzl, Stefan Engelhardt @TU_Muenchen @dfg_public @trr267 👇🧵

[Ali Max Erturk @erturklab]

🚀 Excited to share my journey in transformative tissue clearing for biomedical imaging! Our research at @HelmholtzMunich is making the invisible visible, unlocking new possibilities for medicine and AI-driven discoveries.

[GrazianoMartello @grazianone]

With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory @JZylicz @vincentpasque @Nrivron
https://t.co/cHWDqE0d7i

[Giuliano Granato @Giul_Granato]

Busta paga: 7,84€ l'ora, 24 ore a settimana.
Realtà: 7 su 7, 12 ore al giorno, 2€ l'ora.

Non è che i giovani non abbiano voglia di lavorare; è che sono stanchi di salari da fame e lavori irregolari.

Serve un #salariominimo di 10€ l'ora e un esercito di ispettori del lavoro!

[Daniel Andergassen @DAndergassen]

Excited to share our latest study, published in @NatureComms, on X-linked lncRNA loci and their epigenetic signatures! Here we dissected the in vivo roles of Crossfirre, Firre, and Dxz4, exploring their potential impacts on imprinted & random XCI, as well as on autosomes 👇

[Claudia 🕊 Keller Valsecchi @KellerValsecchi]

The second seXY story of the day 😃 with absolutely #KILLER mouse genetics 🤯🤯🤯 Incredibly well done! 👏👏👏