The FitzGerald Lab

The official page for Dr. Garret FitzGerald's Lab at @PennMedicine

#ProstanoidBiology #MolecularClocks #TranslationalMedicine

Tweets by lab members.

[The FitzGerald Lab @FitzGerald__Lab]

Thrilled to announce our latest publication in @ScienceTM :
"Sexual dimorphism in the response to chronic circadian misalignment on a high-fat diet"

https://t.co/Tq8YJRoeyu

[Penn Medicine CSO @PennMedCSO]

Congratulations to @FitzGerald__Lab (@UPENN_ITMAT), recipient of the 2024 @AAMCtoday Award for Distinguished Research in the Biomedical Sciences! https://t.co/wAHLFENbm1

[ROBIN JOSHI @ROBINJO81170006]

What a great day in the Britton Chance International Symposium on Metabolic Imaging and Spectroscopy, 2024. Grateful for opportunity to share our work with fellow and passionate researchers.
#Lipidomics
#Spatialbiology
@PennMedicine
@Penn
@FitzGerald__Lab

[Penn Medicine CSO @PennMedCSO]

After marrying & welcoming 4 children, Emma Meagher (@PennSysPharmATT) & Noel Williams (@PennSurgery) took a leap of faith to build their careers at @PennMedicine. This year, they celebrate 30 years at @Penn & 35 years of marriage ft. @FitzGerald__Lab https://t.co/ZL2UHLbF9H

[ROBIN JOSHI @ROBINJO81170006]

I am excited to present on "Spatiotemporal lipidomic and proteomic landscape of atherosclerotic plaques in hyperlipidemic mice using imaging mass spectrometry" #ASMS2024 in Anaheim,CA.
#Lipidomics
#Imagingmassspectrometry
#Proteomics
#ThP449
@PennMedicine @Penn @FitzGerald__Lab

[Zoltan Nagy @ZoltanNagyPhd]

Thorough and important study by Soon Yew Tang et al. @FitzGerald__Lab @atvbahajournals comparing the “Differential Impact In Vivo of #Pf4Cre–Mediated and #Gp1baCre–Mediated Depletion of Cox-1” 👏https://t.co/hRe96M7sTW

[NAVBO @vascularbiology]

#NAVBO Member Publication Alert

Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation

Zoltan Arany group @jclinicalinvest 2023 @BoaKim5 @WencaoZhao @FitzGerald__Lab @AranyLab
https://t.co/MjlMglu1B2

[The FitzGerald Lab @FitzGerald__Lab]

Happy to announce an excellent new review by Ricciotti et al.:

Prostanoids in Cardiac and Vascular Remodeling | Arteriosclerosis, Thrombosis, and Vascular Biology @atvbahajournals
https://t.co/GJaCFKo7gC

Congratulations, Emanuela and team!

[ATVB: An AHA Journal @atvbahajournals]

Prostanoids regulate cardiovascular remodeling. Targeting their biosynthesis or receptors have anti-remodeling effects https://t.co/mgX4uBkjUZ

[The FitzGerald Lab @FitzGerald__Lab]

Excellent work by @ThomasB57056224 and the bioinformatics team published today in @NatureRevGenet. Congratulations, all!

https://t.co/dWcTQMhMIp

[ITMATbioinf @ITMATbioinf]

Our article "Challenges and best practices in omics benchmarking" is out today in Nature Genetics Reviews:
https://t.co/ubto3Lx3E8

[Nadim El Jamal @Nadimeljamal]

Diurnal rhythms are linked to disease. In our most recent study just published in @JHHypertension we translate the use of the JTK_CYCLE algorithm from the bench to human blood pressure to detect a subset of CKD patients at risk for CV death.
https://t.co/qakmbzh7xt

[ASCI @the_asci]

ASCI member Garret A. FitzGerald @FitzGerald__Lab @PennMedicine in @JCI_insight: PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice: https://t.co/9JPCcAXneo
#Pulmonology

[Penn Medicine CSO @PennMedCSO]

High fat consumption & blood pressure elevation ft. @BoaKim5, @WencaoZhao, Soon Tang, @MGLevin, @_AyonIbrahim, Yifan Yang, Ling Lai, Jian Li, @FitzGerald__Lab, @AranyLab (@PennCVI/ @PennIDOM) Emilia Roberts & Richard Assoian (@PennSysPharmATT) https://t.co/uVOpjjEw2u

[JCI insight @JCI_insight]

PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice: https://t.co/58aQZcSiL6
@WestPhillyTough @FitzGerald__Lab @PennMedicine
#Pulmonology

[Penn Medicine CSO @PennMedCSO]

Interested in #translational science? Join ITMAT for their 18th annual symposium, “Origins, Emergence, Prediction and Perception of Disease: A Quantum of Solace,” on October 9-10th! Learn more & register for this free in-person & virtual event➡️ https://t.co/SJDNprUoq1

[Penn Medicine CSO @PennMedCSO]

New study out in @NatureComms finds an association between diurnal rhythms of wrist temperature & future disease risk ft. Thomas Brooks, @iScienceGood, @FitzGerald__Lab, @CarstenSkarke (#ITMAT), Gregory Grant (@PennGenetics) & Yvette Sheline (@PennPsych) https://t.co/n7DujGDBVl

[Ronan Lordan @el_ronan]

@kkariko & @WeissmanLab celebrating their @NobelPrize achievement @PennMedicine. It’s not every day you can stroll to work and witness a Nobel Prize! 🥇

[The FitzGerald Lab @FitzGerald__Lab]

Congratulations @kkariko and @WeissmanLab! Well-deserved for your extraordinary work and service to humankind.

#NobelPrize2023

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

[Penn @Penn]

Katalin Karikó and Drew Weissman, Penn’s historic mRNA vaccine research team, win 2023 @NobelPrize in Medicine https://t.co/ztt9x0Iumu #nobelprize

[Society for Research on Biological Rhythms @SRBR_Outreach]

It's often said that disrupted circadian rhythms increase disease risk. But what does 'disrupted' mean? A new study by @carstenskarke's team suggests that the size of the day-night difference, or rhythm amplitude, is predictive of future disease risk:

https://t.co/glKHTch0lm

[Ronan Lordan @el_ronan]

Delighted to be selected as the highlighted author for August in @JPET_Journal by @ASPET made possible by the support of @CarstenSkarke & @FitzGerald__Lab @PennMedicine @PennMedBench