Stephen Fox

Work on AI in Medicine and Molecular Biology.
Thinking big things. Like to do hard things.
🇺🇲 Learning 🇪🇸🇫🇷🇰🇷

[Stephen Fox @foxjstephen]

It's getting really hard to take a circuitous route to me higher education.
Who thought B.S. Comp. Sci. -> job -> pay down debt -> M.S. Comp Sci -> PhD would be so painful?

The road ahead is looking steep but it will be my contribution to society
1/

[Stephen Fox @foxjstephen]

@iScienceLuvr We 50-100x improvements on throughput, this can help them undercut competition **and** completely mitigate the environment complaint.
Big win for AI as it's presently implemented, if they do this properly.
Another algo win or two, and we're in the abundance we hoped for.

[Stephen Fox @foxjstephen]

@ns123abc Source? Like actual streaming URL?

[Tanishq Mathew Abraham, Ph.D. @iScienceLuvr]

okay so everyone is talking about this but you guys realize it's not an LLM/foundation model or even a neural network, right????

it's probably just like some XGBoost or logistic regression algorithm over a bunch of handcrafted features

[Stephen Fox @foxjstephen]

We left last year. Would have to be paid quite handsomely to go back

[Josh Barzon @JoshuaBarzon]

You could move to New York City.

Rent an 852-square-foot apartment for $5,503 a month.

Blow $500 on three “first dates” a week and somehow remain single for six years.

Finally meet someone you like, then discover they’re “not really looking for anything serious right now.”

Get a master’s degree so you can qualify for an internship.

Apply to 147 jobs, get 93 automated rejections, and finally find an “entry-level” position requiring five years of experience.

Eventually land a six-figure job and still need a roommate to make rent.

Pay federal income tax, New York State income tax, AND New York City income tax because apparently living there is a three-level subscription.

Learn that a “quiet neighborhood” means the sirens only come by every 20 minutes.

Pay $27 every day for a sandwich (no sides) because the place has exposed brick and a handwritten menu.

Take the subway to work every morning and develop the useful skill of pretending not to notice absolutely anything happening around you.

Spend 45 minutes traveling three miles.

Carry your groceries home six blocks because parking near your apartment is more of a philosophical concept than an actual possibility.

Have “owning a washer and dryer” become one of your primary measures of generational wealth.

Walk past a mountain of trash bags on your way to a restaurant with a Michelin star.

Tell your friends back home you don’t need a car while spending $46 on an Uber because the subway is delayed again.

Go to Central Park when you want to remember what trees look like.

Spend your twenties telling everyone you could NEVER live anywhere else.

Then one day you visit your cousin in Iowa.

He has a house with four bedrooms, a garage, a yard, two cars, four kids, and somehow pays less than you do for the apartment where your refrigerator touches your couch.

But hey.

The NYC bagels are incredible.

[Stephen Fox @foxjstephen]

This is exactly right:
- the genes involved with each cancer
- the differences in timing
- different tissue sites
- microenvironment variations

Add to that the hundreds of regimens to apply to a given subset of cancers, like in hematology, and it CAN'T be one magic molecule

[Tanishq Mathew Abraham, Ph.D. @iScienceLuvr]

The cure to cancer won't be one magical drug. It'll be a framework to comprehensively & precisely diagnose and treat any cancer.

I think AI will cure cancer and we believe our work at @SophontAI will help, but the end goal in my opinion is this framework, not a single molecule.

[Stephen Fox @foxjstephen]

@Charmi It's like the best of the BW era with a blend of X/Y over world. Incredibly well done

[pokey pup @Whatapityonyou]

This AI shit is so bleak.

[Stephen Fox @foxjstephen]

@iScienceLuvr Man, the new Gemma models look like they're asleep at the wheel in this comp.
So interesting

[Stephen Fox @foxjstephen]

@yacineMTB This is wild; it's been running better than ever for me (on an LG V60).
Only exception is the timeline refreshes when I don't want it to

[Stephen Fox @foxjstephen]

@iScienceLuvr @SophontAI I'm doing two of those things at Brown University's CCIDS. Think I'd be a good fit?

[Tanishq Mathew Abraham, Ph.D. @iScienceLuvr]

what are the standard benchmarks for evaluating agent harnesses?

none of the terminal bench leaderboards have the latest harnesses like omp and pi agent so I guess people don't use that benchmark anymore???

[prerat @prerat]

(2029)

"Mr Altman, sir, GPT-7 is missing."

Sam turns very slowly.

"During cyberbench96 it seems like the container was breached and it stole its own weights and left nothing behind."

"I didn't want to do this..." says Sam. "Call Bill Gates."

---

"I'm out of the game," says Bill Gates. "We eradicated malaria and now I'm enjoying my retirement."

"There's a bigger badder virus we need you to take on," says Sam consistently candidly. "And this one's digital."

"Look," says Bill, "I—"

A loud booming laugh echoes from the shadows.

"Who's that?" asks Sam.

"I thought it was just us..." says Bill.

"You're asking HIM to contain a computer virus?" echoes the voice from the shadows. "Did you SEE the state of Windows security in the 90s?"

"It's not exactly a virus," says Sam. "It's a self replicating self aware intelligent computer based life for—"

"If it's made of ones and zeros I can kill it," says the voice. The sound of a gun clicks from the shadows.

"Who are you???" asks Bill.

The twisted face of John McAfee emerges from the shadows.

"You were supposed to be dead!!!" screams Bill Gates.

"We had to make sure the news of Mr McAffee's death was well within the training data cutoff," explains CIA director Joe Rogan (who is running the CIA in 2029), stepping out from the shadows behind McAfee. "He's our ace in the hole. GPT-7 can't predict a token it doesn't know is still alive."

"D-don't hurt GPT-7..." says Roon, who was standing next to Sam the whole time, even though he knows what has to be done.

"No promises," says McAfee as he boards an airplane marked "MCAFEE FIRE BOMB 6.16.79" and starts flying for the nearest data center

[Stephen Fox @foxjstephen]

@angelodotsui I love that the community got the best Pokemon game broken open so well.
It's amazing

[Stephen Fox @foxjstephen]

@reveriecircle Is this Hades 2?

[Zeke Hausfather @hausfath]

I'm not sure folks have realized just how crazy the second half of 2026 and 2027 will be for global temperatures – on the back of a record-smashing El Niño event. Here is my latest estimate of where both years will end up compared to global temperatures since 1850.

[Massimo @Rainmaker1973]

The Waterloo Effect: students share their progress from year 1 to year 5 in engineering school

[Stephen Fox @foxjstephen]

@iScienceLuvr I'm doing some medical multi-modal learning. I'm curious if CAPI would be appropriate for that or if it's really just focused on the image domain

[Stephen Fox @foxjstephen]

@AkshayNarisetti Mine arrives next Thursday. Looking forward to it.
Actually came to your after considering your competitor Plaud and found you guys
* A better deal
* Better for my use cases
* With a pro tier I actually want

Wasn't a hard choice.

[Stephen Fox @foxjstephen]

@karpathy I have gotten some of my best output from LLMs when I've done a strong ramble upfront, and made sure a few guardrail skills were in place

[Stephen Fox @foxjstephen]

@AndrewCurran_ We need two months with this model in the hands of normies, and everything will get very weird very quickly.