Happy to share env-MR-MEGA - first in our suite of environment-adjusted #GWAS methods
Use summary-level data to quantify environmental and ancestral heterogeneity
Amazing teamwork with @SiruRooney, @SolaOjewunmi, @ab_kamiza, Michele Ramsay, Andrew Morris, @tchikowore1, @SFatumo
New preprint - genetic analyses of latent factors from high-dimensional traits give enhanced power for #GWAS discovery and #finemapping
Highest gains are through multi-trait fine-mapping of latent factors - we introduce flashfmZero
@FZ_Cambridge, @WilliamAstle, @aidanbutty
Fantastic news!
We used multi-trait approaches to identify additional loci associated with lipids traits (MTAG) and refine 99% credible sets (flashfm) in 125,000 individuals of African ancestry
@ab_kamiza, Sounkou Touré, @FZ_Cambridge, @tchikowore1, @SFatumo@MRC_BSU
BSU researchers @FZ_Cambridge and @JennAsimit have made video tutorials of how to use their R shiny apps and flashfm-ivis software.
Fine-mapping of multiple quantitative traits.
Watch videos here 👇
https://t.co/swq7w5tYe7
New all-in-one web tool!!!
Explore and fine-map GWAS signals of traits in UK Biobank with many user-controlled features.
See: https://t.co/CKFb7gcxpc
Preprint at: https://t.co/Fb1P0waIhO
@FZ_Cambridge@aidanbutty@MRC_BSU@CAMBRIDGE_CEU
New interactive statistical tool, flashfm-ivis, developed by @JennAsimit, @FZ_Cambridge & colleagues to explore potential causal variants behind diseases.
https://t.co/RMIVBugA2Z
https://t.co/9RFjfQzFUS
Excited to share that our interactive visualisation tool for fine-mapping, flashfm-ivis, is out in Bioinformatics
https://t.co/kJyP7SWN87
@FZ_Cambridge@aidanbutty@MRC_BSU@CAMBRIDGE_CEU
Plot and Play! View potential causal variants that are shared or distinct between traits
Excited to share that our interactive visualisation tool for fine-mapping, flashfm-ivis, is out in Bioinformatics
https://t.co/kJyP7SWN87
@FZ_Cambridge@aidanbutty@MRC_BSU@CAMBRIDGE_CEU
Plot and Play! View potential causal variants that are shared or distinct between traits
New interactive visualisation tool!
Plot and Play with multi- and single-trait fine-mapping results – view potential causal variants that are shared or distinct between traits
@FZ_Cambridge@aidanbutty@MRC_BSU@CAMBRIDGE_CEU
https://t.co/3x4b1qgBwW
https://t.co/ARSnJHA3Nm
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