Gorkem Garipler, PhD

Senior Scientist @PatchBiosciences | Ph.D. @EstebanMazzoni Lab @NYU

[Gorkem Garipler, PhD @ggaripler]

Our work on transcription factor-wide CRISPR screen identifying essential TFs for stem cell pluripotency is officially out @CellReports!🎉 Special thanks to my advisor @EstebanMazzoni and collaborators @nevillesanjana and @congyilv for this great work!
https://t.co/vrE8iM4uIA

[Gorkem Garipler, PhD @ggaripler]

Super excited to share our latest publication
@NatureComms
identifying transcription factors required for neuronal differentiation with a CRISPR KO screen! 🥳 Coming from a great team w @congyilv @chaodai @nevillesanjana @EstebanMazzoni 🚀

[Neville Sanjana @nevillesanjana]

TWEETORIAL time! In new work, we identify required transcription factors for neural differentiation using a TFome-wide CRISPR knock-out library.

Congrats to first authors @congyiliv and @chaodai (from our lab) and @ggaripler (from @estebanmazzoni lab). 👏👏👏

[Muharrem İNCE @vekilince]

Seçimlere dair...

[Yılmaz ÖZDİL @Yilmaz_Ozdill]

Asla unutturmayacağımız bir gün… 20 yıldır karşı devrimle mücadele eden Mustafa Kemal’in askeri İzmirlilere bugün, mutant gazetecilerin borazanlığında, Davutoğlu’nu, Babacan’ı, kumpasçı The Taraf yazarını alkışlatacaklar

[Muharrem İNCE @vekilince]

AKP artıkları, eski partilerindeki tek adam zihniyetini aynen Millet İttifakı'na taşımış görünüyorlar. Bu tipler hiçbir zaman demokrasiyi içlerine sindiremediklerinden dolayı, sürekli her bulundukları ortamda "tek adam, tek seçenek" yaratma gayreti içinde oluyorlar. Milletimiz "tek adam" dayatmalarına seçim günü sandıkta gereken cevabı verecektir.

[Muharrem İNCE @vekilince]

Sayın Ali Babacan'ın hakkımda söylediği "Bizim eskiden de bir hukukumuz yok ki Sayın İnce'yle" sözü, sonuna kadar doğru. Benim ne geçmişte ne de bugün bu tiplerle bir hukukum olmadı, olmayacak.

[Gorkem Garipler, PhD @ggaripler]

@begum_aydin_ @FrontNeurosci @EstebanMazzoni @mahonylab Congrats @begum_aydin_!!!

[Tamer Onder @Tamer_Onder]

Holy grail of human reprogramming published ⁦⁦@Nature⁩ : Chemical reprogramming of human somatic cells to pluripotent stem cells https://t.co/1BUJIgJxM1

[Atilgan Yilmaz @Atilgan__Yilmaz]

Analysis of haploinsufficiency in human embryonic stem cells with a unique system that allowed the generation of a genome-wide heterozygous mutant library. Kudos to Roni Sarel-Gallily! https://t.co/aR469ViZiT @CellReports

[Tamer Onder @Tamer_Onder]

We are looking to recruit a postdoctoral fellow to work on chromatin modifiers in reprogramming, induced pluripotent stem cells and blastoid models of early human development. 🔬🧫🧬
See : https://t.co/lo3v83E5Dp for info about our lab.
And please share!

[Esteban O Mazzoni @EstebanMazzoni]

Amazing work here providing a much needed tool by @WenjunK @morris_lab @ggaripler

[Gorkem Garipler, PhD @ggaripler]

Super excited to share our latest publication @CellStemCell describing a new resource for measuring cell identity during differentiation and reprogramming! This great work is led by @WenjunK and @morris_lab. Congrats to all authors! @EstebanMazzoni

[Samantha Morris @morris_lab]

Our latest paper is online @CellStemCell! Capybara: A computational tool to measure cell identity and fate transitions https://t.co/oO78go18Qz led by @WenjunK

[ESC & iPSC News @ESC_iPSC_News]

Drs. Görkem Garipler (@ggaripler) and Congyi Lu (@congyilv) used a #CRISPR screen to identify ZBTB11 and ZFP131 as required transcription factors for #pluripotency.

🖇️ Read the @CellReports paper from Dr. @EstebanMazzoni's group: https://t.co/ulo4l5hQUm

[Shaun Mahony @mahonylab]

This is really great work from @ggaripler and @congyilv, using a CRISPR screen against all TFs to find two new zinc-finger regulators of pluripotency. Lexi Morrissey from our lab helped characterize the genomic binding of those TFs.

[Neville Sanjana @nevillesanjana]

Congrats to @congyilv from our group and @ggaripler from @EstebanMazzoni lab on this new study that uses TFome-wide CRISPR libraries (🐭 & 🧑‍🤝‍🧑) to find essential TFs to maintain pluripotency. 👏

Stay posted for more great work from Congyi & Gorkem still to come.... 🙂

[Esteban O Mazzoni @EstebanMazzoni]

This is Finally out!
Beautiful work by @ggaripler with @nevillesanjana @mahonylab identifying a pair of TF that maintain pluripotency by repressing pro-differentiation genes
https://t.co/7SSprZKkcp

[Gorkem Garipler, PhD @ggaripler]

Many thanks to our amazing collaborators @mahonylab for their analysis during identifying mechanisms of these TFs, @uwe_ohler & @lsofialz for their input on screen analysis, and to the rest of the team @YingzhenP @Anazenfiore @begum_aydin_ @SimonVidalV!

[Gorkem Garipler, PhD @ggaripler]

Our work on transcription factor-wide CRISPR screen identifying essential TFs for stem cell pluripotency is officially out @CellReports!🎉 Special thanks to my advisor @EstebanMazzoni and collaborators @nevillesanjana and @congyilv for this great work!
https://t.co/vrE8iM4uIA

[Sudarshan Pinglay @sudpinglay]

Excited to share our preprint with @BulajicMilica @JefBoeke @EstebanMazzoni on applying our ability to build big pieces of DNA (>100kb) to the problem of mammalian gene regulation at the HoxA cluster

(short videos summarizing the study are below)

https://t.co/G16HXNbDn6