Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology in JBO - work by postdoc Yuli Heinson and PhD student Julie Han. One of two technology development papers. Highlighted by SPIE
https://t.co/rRSVTD66XA
Our article on parasystole is now out in PRL, with a APS news commentary by Phillip Ball. Congats to Khady, Tom, Leon and the rest of the team! News: https://t.co/UOa1lDJFeZ
Article: https://t.co/xhg7y5tlLk
And an optical mapping paper with Yuli Heinson and Julie Han - Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology https://t.co/Oitze02Pfv (there is a companion ms to be deposited).
Yet another cool paper by Leonardo's group: Fast Optical Investigation of Cardiac Electrophysiology by Parallel Detection in Multiwell Plates https://t.co/nwdvm13sA4
We present rapid projection imaging under variable viewing angles. We apply this method in light-sheet and spinning disk microscopy to visualize 3D samples in real time. We further demonstrate that 3D information can be gathered from a set of projections. https://t.co/d1fNqLYNCv
ChR2 cell spheroids were manufactured, cryopreserved, thawed and successfully deployed for cardiac pacing; integration was faster than it takes to genetically modify the cardiac cells.
Join us on Thursday 17 June, 6-7pm to hear from @GaryMirams. His lecture on Mathematical Matters of the Heart will explain how simulations are assessing the safety of new medicines. Open to all, booking required. https://t.co/KcTutJfe7y
@Maurice_Y_Lee Alternative implementations are available! At @UniofExeter we replace the reflector with a smaller transmissive lens to study the feeding habits of sea worm larvae (different food stock in each well). Credit: @MarInvMet and BSc student Natalie Wood.
Are you struggling to image multiple samples at the same time? A new high-throughput imaging system allows parallel imaging in a 96-well plate! Which dynamic process would you image? https://t.co/iKFwQZq4fT
Our Random Access Parallel ('RAP', previously 'ssHTS') #microscopy paper is out in elife:
https://t.co/gaQLQNy94z
(@McGillPhysioloG, @alexdcorbett, @SharikaMohanan)
RAP in action with a c-elegans prep:
Most imaging objectives try to minimise chromatic aberration. In this paper we exploit it to provide wavelength-dependent refocusing of brightfield images. DOI: 10.7554/eLife.56426
Creative new random access #microscopy from @gilbublab - high throughput, fast, no moving parts, using a reflector ala Newtonian telescope, #LED addressing, single camera, <$5000, #cardiac, C. elegance #imaging
https://t.co/g3viSSx0mX
It was fun working on this review with Matt @mwkaylab, covering the opportunities #optogenetics has brought to the #heart since 2010, when first used by @huiskenlab, P. Sasse, T. Bruegmann, O. Abilez, D. Pijnappels and several other labs including mine.