Gino Ghioane

Passionate about AI, No-Code, autonomous organizations, and all the words with "tech" as a suffix (biotech, nanotech, etc.) 😂 How can I help? 🫶🏼🕉️

[dotta 📎 @dotta]

https://t.co/Kgdi4OsOrL

[Raphaël Dabadie (YC P26) @RaphaelDabadie]

https://t.co/DMhD8uaiUm

[Gino Ghioane @ginoghioane]

@vladstan Or you can look into Outcome-Driven Innovation :) 🤗

https://t.co/pAdANPuazL

[Gino Ghioane @ginoghioane]

“What seems more likely is that people use death to shield from the disappointment of not experiencing the potential of life without the limitations of death.”

[Bryan Johnson @bryan_johnson]

Ok, here is my trip report from 4.67 grams of magic mushrooms, 24.9 mg of psilocybin. The dose used in modern clinical trials.

First, the experience was exhilarating. Positive in every way. I felt like a kid finding and exploring a new playground.

My sensory perception was dialed up to levels I must have felt as a kid but have been dulled with time. I experienced sense of touch with awe. Feeling my fingers rub together felt novel. Touching my skin and running my feet over the threaded quilt lit up my brain. It seemed that my mind was insatiably curious and wanted to deploy its sensors into the world and discover all things.

I felt the same sensory joy in moving my body. Rolling my joints, curving my back, curling up in a ball, flexing muscles and moving all about in a fluid fashion. My body felt nimble, supple, fit, and strong.

My sense of hearing was equally as elevated. It helped that I was also wearing my new hearing aids which restore frequencies I’d long stopped noticing. The music I listened to hit more fully than I have memory.

My facilitator gave me some water in a glass jar. The visuals of the light reflections, water dynamics and sensory experience of holding the glass were so fascinating that I forgot to drink. My brain wanted to stare, study and marvel.

One of the most satisfying things I discovered was taking huge, deep breaths. Inhaling life and fueling the body’s needs and wants. I did it over and over and over. This material of existence, all around us, was available and free to be mined. You just needed to breathe in.

(After peaking and coming down, I ate a salad. It tasted like the most delicious food I’d ever eaten. The flavor exploded in my mouth. I savored every bite.)

At one point, I felt like my entire body was still. I had a perceived sense of total body control.  Like my heart had stopped. Complete stillness. This was surprising as I’m acutely tuned to my heart beat. I monitor my heart all day every day and can usually discern my heart rate by sensation. In that moment, I couldn’t feel my heart beat or any pulse pressure through my blood vessels. First time that’s ever happened. I asked Kate to check my heart rate on my wearable and it was mid 50s. I wasn’t worried. Just curious about my sensory experience.

With this heightened sense of sensory perception, it felt like my consciousness was dialed up to 10/10. I felt hyper aware and hyper alive.

It felt like mushrooms restored my perception to youthful levels, returning them to factory settings and dissolving my aged numbness.

Once my senses were reset, my attention sifted from the texture of existence to existence itself.

We spend most of our time playing games at the layers of people, dramas, companies, politics, jobs, money, ideologies, and status.  Underneath these games is the knowing that physical death has been inevitable. Everyone before us has died.

When death is inevitable, people pick their game among a wide array of options including reincarnation, heaven, legacy, offspring, ancestral veneration, existentialism and many more. These frameworks make death soothing, a virtue, and something positive to be anticipated.

But what if death is no longer inevitable? I’m not suggesting immortality. I am suggesting a radical remake of human life. The speed of progress in AI, biology and medicine point to a new frontier of possibility. Are we cavemen-equivalent now compared to what we will be like in 50 years? It’s now harder to argue why we should limit our imagination.

With so much promise, why have we not shifted our societal attention to secure our own existence? To solve aging. To address existential risks. To care for our planet. Why are we still messing around with self destruction, war and ignoring preserving our own existence?

We work hard to be fit. To learn a skill.  Build a relationship. To make money. When we identify an opportunity, we focus and work hard. It seems to me that we’re not yet aware or awake to the opportunity of what existence could become.

Whatever one’s life philosophy and belief of what happens after this life, the majority of us want to live to see tomorrow. We have stuff going on and things to look forward to. And when tomorrow arrives, we want to see the next day. Wanting tomorrow is functionally equivalent to wanting infinitely.

The want to exist is deeply embedded in all of us. Our actions prove this every day.

Humans have been the alpha form of intelligence for a while now, imposing our will upon all we can. Our powers have increased dramatically in the past few decades. We can edit our own DNA, design materials at the nano scale, and build thinking machines.

Our alpha status is now challenged by AI. Whether AI is friend or foe, and in what ways, and on what timelines is anyone’s guess. No one knows.

Mushrooms opened up my sensory awareness of this landscape to depths I hadn’t accessed before. My ability to see and understand felt like the movie Inception, where characters take a sedative to enter a different realm to carry out missions. A space as real as what we experience each day, but with different foundational pillars of reality.

It felt convincing that without the aid of a reality expanding intervention (like mushrooms), you can’t really see or understand this dimension, handicapping awareness.

While in this mushroom-induced dimension, it felt clear that we are about to start waking up from a slumber that has hypnotized us into accepting death. This will happen faster than people think. Once people see a practical path to extending a healthy life, they will adopt ferociously.

The body positivity movement came to mind. Most people don’t really want to be overweight and unhealthy. But when we want something we can’t achieve, we come up with moral frameworks about why we didn’t want it in the first place (i.e. sour grapes). Once GLP-1s came about, people’s attitudes changed overnight. The same will happen with aging. No one wants to be crippled and handicapped by age.

This awakening will also come about with the emergence of new ideologies.

Revolutions erupt when a civilization’s founding myth becomes incompatible with its reality.  The system fractures, dissolves, and opens up space for new meaning to rush in and replace it.

This pattern has been repeated throughout history.

> The agrarian empires (800-200 BCE) ruled via tribal power and violence, creating a moral crisis that gave rise to Buddhism, Greek philosophy, Judaism and Confucianism.

> Feudalism (1600-1800) ruled via divine monarchy, creating a stagnation crisis that gave rise to rational inquiry, the scientific method, individual rights and democracy.

> Industrial capitalism (1848-1945) ruled via mechanization and labor exploitation, creating a crisis of alienation, mass poverty and urban chaos that gave rise to socialism, nationalism, regulation and collective rights.

> Liberal capitalism (1980-2025) ruled via consumer sovereignty and free markets, creating a crisis of attention capture, metabolic collapse and existential despair that will give rise to something new. Capitalism solved for scarcity. Its defining virtue was freedom to choose. Ironically and perhaps inevitably, compulsion replaced scarcity and freedom decayed into addiction.

Revolution is at our doorstep.

Our current systems are fractured, evolving, and opening up space for new meaning to rush in and replace it. Change has been a reliable feature of human society. It will happen on accelerated timescales given the pace of technological and scientific advance.

After journeying this terrain, I was left feeling unbridled enthusiasm for the future of existence. That we may be the equivalent of cavemen trying to anticipate a future that is unimaginable to our current minds. And that existence could be more exquisite than any can actually paint at this moment.

New archetypes will emerge: warriors and caretakers of existence. People who are defiant of death, and view self-destruction as primitive and low-status.  Who take the continuation of human existence as seriously as profits, fame or power. They will emerge as our high-status societal idols.

The irony is that people thought this experience would collapse my interest in life and have me willfully kneeling to death.

To find truth though, one must always invert.

What seems more likely is that people use death to shield from the disappointment of not experiencing the potential of life without the limitations of death.

[Gino Ghioane @ginoghioane]

@pk_iv Yep, other than Outcome-Driven Innovation… there are no shortcuts!

[Ethan Mollick @emollick]

Just a reminder that you can build a lot of different things with AI, and some of them can clearly help the world & some of them are going to make the world worse.

In addition to AI labs and AI users having responsibility for outcomes, all you builders and startup folks do, too.

[Anna ⏫ @annapanart]

It’d be a romantic experience to grow young together. 🥹

👵🏼👴🏻——👩🏻🧔🏻

[Vlad Stan 🔭 @vladstan]

It's probably the best metaphor for what it means to be a founder.

[Gino Ghioane @ginoghioane]

@SadhguruJV @S_Kartushina If it s not a tsunami?! 🤣

[Gino Ghioane @ginoghioane]

@toniengelhardt do you have any plans to integrate image gen into @PromptmetheusAI

[Francis Lucille @FrancisLucille]

Second Dialogue Between Francis Lucille and Dr. Bernardo Kastrup: Is AI Conscious?
https://t.co/YMVDgxphzW

[Gino Ghioane @ginoghioane]

@elonmusk I need a dislike button for this one! This is 100% unbiased , aha!!

[Gino Ghioane @ginoghioane]

@conspiredlife @stoimeniliev @sama I believe he meant that if DeepSeek R1 hadn’t been released, we wouldn’t be seeing O3 right now. OpenAI tends to release things when the industry pressures them, rather than when they have something truly new to offer. 😉

[Gino Ghioane @ginoghioane]

@annapanart It depend on what you mean by “I”! If you think about youself as something limited then no, otherwise, yes! 🤣

[Unitree @UnitreeRobotics]

Unitree G1 Bionic: Agile Upgrade 🥰
Unitree rolls out frequent updates nearly every month. This time, we present to you the smoothest walking and humanoid running in the world. We hope you like it.
#Unitree #AGI #EmbodiedAI #AI #Humanoid #Bipedal #WorldModel

[Dr Singularity @Dr_Singularity]

AGI won’t ‘replace’ humanity. It will help us replace all the things holding humanity back

[Dr Singularity @Dr_Singularity]

The robots won’t take over. They’ll take us further

[Dr Singularity @Dr_Singularity]

Huge breakthrough

New AI unveils strange chip designs, while discovering new functionalities, it's also slashing the time and cost of designing new wireless chips

"In a study published in Nature Communications researchers at Princeton Engineering and the Indian Institute of Technology describe their methodology, in which an AI creates complicated electromagnetic structures and associated circuits in microchips based on the design parameters. What used to take weeks of highly skilled work can now be accomplished in hours."

"Moreover, the AI behind the new system has produced strange new designs featuring unusual patterns of circuitry. Kaushik Sengupta, the lead researcher, said the designs were unintuitive and unlikely to be developed by a human mind. But they frequently offer marked improvements over even the best standard chips."

"We are coming up with structures that are complex and look randomly shaped, and when connected with circuits, they create previously unachievable performance. Humans cannot really understand them, but they can work better," said Sengupta, a professor of electrical and computer engineering and co-director of NextG.

[Gino Ghioane @ginoghioane]

@icreatelife

[Gino Ghioane @ginoghioane]

@annapanart That which is reading this words right now 😉