Rodrigo Grassi-Oliveira

An Italian-Brazilian living between Brazil and Denmark. Aroid collector 🌱🍃interested in Early Life Stress & Addictions 🏳️‍🌈

[Rodrigo Grassi-Oliveira @grassirod]

Reforçando o compromisso da PUCRS com a ciência e a pesquisa no Brasil, oito pesquisadores da Universidade integraram o levantamento da plataforma Ranking Research, que destaca os cientistas de maior prestígio no cenário internacional. https://t.co/1aHojY5JZU

[Rodrigo Grassi-Oliveira @grassirod]

@e_brietzke Até ressurgi das masmorras do Twitter para citar a Odete Roitman original: “Dama de circo eu detesto desde criança. Vamos Celina. Com licença minha filha, se você precisar de alguma coisa, nós estamos aqui na ante-sala”. Democratização da ciência e seus efeitos paradoxais 🤌

[Rodrigo Grassi-Oliveira @grassirod]

@Grimezsz within faith, yes: God is reliable by definition, I just don’t have it 🫣

[Rodrigo Grassi-Oliveira @grassirod]

@Grimezsz “I contain multitudes. Do I contradict myself? Very well then, I contradict myself; I am large, I contain multitudes.” Whitman within The Life of Chuck

[Rodrigo Grassi-Oliveira @grassirod]

🚨 Excited to share our latest preprint: "Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes” #ExtracellularVesicles

https://t.co/QJXuwFT1DY

[JAMA Psychiatry @JAMAPsych]

A study of 25,252 Swedish twins indicates that adverse childhood experiences associated with elevated risk of adult psychiatric disorders notwithstanding considerable familial (genetic & early environmental) confounding revealed through MZ/DZ comparisons. https://t.co/Oc2hYCFH0N

[Eric J. Nestler, MD, PhD @EricJNestler]

Please see this new review on Neurobiology of Resilience by @ScottRussoPhD and me which just appeared online in @NeuroCellPress.
https://t.co/EVg0mkXeKy

[HappyMums Project @HappyMums_]

Meet Professor @grassirod, group leader at the Aarhus University. In the #HappyMumsProject🤰🧠 , he will guide the investigation of the sex-specific biological mechanisms underlying offspring risk to prenatal maternal depression. #perinatalmentalhealth #horizonproject

[Martin Picard @MitoPsychoBio]

The organism is a network of communicating, energy transforming mitochondria

https://t.co/mlpaJSLLAV

[HanganuOpatzLab @HanganuOpatzLab]

We are thrilled to share our latest paper published in @NatureComms! We report that sharp-wave ripples emerge around postnatal day 10, driven by the maturation of inhibition.
Brought to you by @IPochinok, @chini_mattia, Jochen Triesch, and @tristanstoeber.
https://t.co/CeyfBKeCua

[Rodrigo Grassi-Oliveira @grassirod]

🫶🏻

[Rodrigo Grassi-Oliveira @grassirod]

We profiled genome-wide DNA methylation (DNAm) of umbilical cord blood from newborns with and without cocaine exposure during pregnancy. We used DNAm data to (1) assess pediatric epigenetic clocks at birth and (2) to estimate epigenetic scores (ES) considering the large-scale DNAm data availability and existing evidence regarding prenatal cocaine exposure (PCE) as a risk for health problems later in life. We generated ES for tobacco smoking, psychosis, autism, diabetes, and obesity.

PCE was associated with protracted DNAm gestational age in newborns, and this effect remained significant when controlling for potential confounders, such as blood cell type composition predicted by DNAm and obstetric data. DNAmGA was negatively correlated with BDNF levels in the serum of UCB. Higher tobacco smoking, psychosis, and diabetes ES were found in the PCE group. The GO analysis revealed GABAergic synapses as a potential pathway altered by PCE.
@WViolaThiago @FriesGabriel

https://t.co/DV1KP1U1Mz

[Rodrigo Grassi-Oliveira @grassirod]

I am glad to announce it is official! We got the Better Framework for Psychiatry @DFF_raad grant! I can only think about I Ching Hexagram 53, Ji’an: “The best progress is slow but steady—slow enough to allow for bonds to knit properly and steady enough to keep moving in the right direction. A firmly rooted tree has deep roots and is not easily toppled.” Thanks Chioma Okeoma (NYMC), Chelo Walss-Bass (UTHealth) and @WViolaThiago (PUCRS) for the partnership!

[Rodrigo Grassi-Oliveira @grassirod]

@TWBredy @Paul_R_Marshall @AusNeuroSoc Handsome 😃

[Thiago Wendt Viola @WViolaThiago]

By using machine learning we found clinical and psychosocial variables that can be assessed in real-world clinical settings, potentially helping clinicians to identify individuals with severe cocaine withdrawal that is likely to be sustained over the course of detoxification.

[Schratt lab @SchrattL]

Save the date: Meeting on brain non-coding RNAs coming up in October 2024 in beautiful Ascona, Switzerland. Impressive line-up of speakers. Registration will open in March 2024. Visit https://t.co/h00R7c3KJZ for more info.

[Rodrigo Grassi-Oliveira @grassirod]

Thrilled to receive the Lundbeckfonden Ascending Investigators Grant 2023! 🥳 Exploring how THC & CBD during pregnancy impact brain cells DNA & future cognitive abilities. Let’s build bridges between Aarhus University 🇩🇰, PUCRS 🇧🇷, and Karolinska Institute 🇸🇪! 🧠🔬 #THC #CBD #Neuroscience @lundbeckfonden @AIAS_dk @AarhusUni

[Rodrigo Grassi-Oliveira @grassirod]

Dan Stein 🇿🇦

[Rodrigo Grassi-Oliveira @grassirod]

@WViolaThiago

[Rodrigo Grassi-Oliveira @grassirod]

Cocaine use disorder effects on blood oxytocin levels and OXTR DNAm https://t.co/PMLdylaSJe