MG

[MG @grayfluorprot]

@betowbin @FluoProt @joachimgoedhart Not a single point mutation but the spaghetti monster FPs mutated the 65-67 SYG of GFP to GGG to create dark variants https://t.co/VXT7BiYZpA

[MG @grayfluorprot]

@SamantLab @AndrewWoodLab It’s pretty tough to have a stable C-terminal tag for Ub though

[MG @grayfluorprot]

@PShannonNeuro Hamartoma didn't fit with the aneuploidy anyways.

A. Olives, prominent because of lack of pyramids. But are really prominent.
B. Histology?
C. Dorsal cyst wall from a better dissector than me.
D. Fused thalami
E. Choroid plexus

Any polydactyly?

[MG @grayfluorprot]

@PShannonNeuro Let’s see if I’m on the right track. B. Hypothalamic hamartoma. D. Fused/single superior colliculus

[MG @grayfluorprot]

@PShannonNeuro @gemistocyte I think a genetic cause is odd for left-sided unilateral PMG. Isolated left MCA ischaemia? Maternal ischemia or infectious would be bilateral. Is there a vascular lesion/abnormality?

[MG @grayfluorprot]

@PShannonNeuro Hemimegalencephaly. Look for cutaneous vascular lesions, poly/syndactyly.