Greg Tyrelle

Personal account, foucsed on health, fitness and programming 🇳🇱 🇹🇼 Oh, and maybe some Drum and Bass

[Jarno N. Alanko @[email protected] & Bluesky @jnalanko]

I asked ChatGPT to write a FASTA parser. It returned a fully working Python implementation with comments and everything. I asked it to port it to Rust. It did that, and produced a correct Rust program that compiles without any warnings. What is this sorcery??!

[Richard Kadrey @Richard_Kadrey]

https://t.co/wiVIcRlgpN

[Turing Post @TheTuringPost]

🔥3 free data science books, the most popular among our subscribers!

1. Fundamentals of Data Visualization by @ClausWilke
2. Python Data Science Handbook by @jakevdp
3. Hands-On Data Visualization by @HandsOnDataViz

Links⬇️

[Jonathan Jacobs 🧬🦠🕹️🏕️ @bioinformer]

At @nanopore’s pathogen event - @laura_boykin urges the global #publichealth community to stop doing “labs in a suitcase” and colonial science, but instead focus on building local in country infrastructure and jobs. #ASMicrobe

[Nils Homer @nilshomer]

@OmicsOmicsBlog @erlichya @UltimaGenomics Flow order can be leveraged for basecalling, mapping, and variant calling. Ion Torrent did this extensively.

[Nick Murphy @NicholasMMurphy]

Our article on preconception/preimplantation screening human embryos for pathogenic variants & mutations with #WGS https://t.co/jYiH3uA2lK #genome #genetics

[Erik Garrison @erikgarrison]

Evolution is tree-like, but not a tree. This is why in pggb we make genome graphs without a guide tree. Looking for further support of this, including study targets (clades and species), to convince ever-skeptical grant reviewers of the importance of this https://t.co/Ccg1H59nbo

[Nuria Lopez-Bigas @nlbigas]

Mutational signatures extracted from more than 12000 tumor whole genomes from #100kGenomesProject, including common and rare signatures.
Great work by @SerenaNikZainal team!
https://t.co/RmFG8rCL1J

[Paul Bieniasz @PaulBieniasz]

Wuhan-Hu-1. Alpha, Beta, Delta Omicron/BA.1, BA.2, BA.4, XE, XD, XF.

Once again, biologists do a bang-up job when it comes to nomenclature

[Sam Nicholls @samstudio8.bsky.social @samstudio8]

No less than four months since @MRCClimb's CLIMB-COVID pipelines reached the staggering and sombre milestone of 1 million genomes, we've done it all over again and the count now stands at over 2 million UK SARS-CoV-2 genomes🧵Thread on how our system works https://t.co/Bcg1HkTrcV

[Yoeri Albrecht @YoeriAlbrecht]

Hier schieten je toch de tranen van in de ogen! #opendecultuur

[Juleen R. Zierath @JuleenRZierath]

Atlas of exercise metabolism reveals time-dependent
signatures of metabolic homeostasis is now online @Cell_Metabolism Great collaboration w/@s8shogo @DyarKen @treebak @lutter_dominik @sassonecorsilab @srp_diabetes @Metabolcenter https://t.co/RdCIysw5ex

[Liz Worthey @lizworthey]

Bioinformatics (me paraphrasing: tools and methods) are 31-fold over-represented among the highest impact scientific papers of the past two decades https://t.co/pm8uubjhJE

[michi @archisound]

バインコルフストア1931atロッテルダムbyウィレムマリヌスデュドック

[📊 Ruben van Gaalen @rubenivangaalen]

Cumulative numbers diff age groups:
1⃣ Excess mortality (wk 50)
3⃣ C19-deaths, death certificates (wk35)

Since start vaccination campagne, in which 80+ and care home pop. got vaccinated first, 1⃣ did not increase for long time. Among 65-80 yes, but 1⃣ = 3⃣ during that period.

[📊 Ruben van Gaalen @rubenivangaalen]

3 types of mortality data per week in 1 graph:
1⃣ Excess mortality (EM, wk50)
2⃣ Reported deaths of C19 patients (wk 50)
3⃣ C19-deaths based on death certificates (wk35)

Untill now 3⃣ as high or much higher than 1⃣ or2⃣.

Recently, 1⃣ is really much higher than 2⃣.

[📊 Ruben van Gaalen @rubenivangaalen]

3⃣ Statistics Netherlands published Cause of Death statistics, based on info of medical doctors. CBS publishes figures on this since 1899. The C19 outbreak presented CBS with a challenge that had not arisen since the Spanish flu. Explainer:
https://t.co/FZgx6y3GFJ

[📊 Ruben van Gaalen @rubenivangaalen]

💡May be of interest for non-Dutch: a short explainer on the 3 sources of mortality data in the Netherlands🇳🇱.
1⃣ Total and excess mortality
2⃣ Reported deaths of C19 patients
3⃣ C19-deaths based on death certificates (filled in by MD)

@statisticscbs @GGDGHORNL @rivm

/Start 🧵

[UK Health Security Agency @UKHSA]

Our new variant technical briefing contains updated analysis on Omicron hospitalisation risk and vaccine efficacy against symptomatic disease and hospitalisation: https://t.co/254m2rwJN5

[sandeep chakraborty @sanchak74]

However, significant problems remain - these are long stretches of unknowns.

https://t.co/CvIWiUD4hl