Immunologist, group leader at Imperial College London.
We investigate the functional implications of Natural Killer cells and NK cell receptors in Cancer.
Shifting our attention to #cancer, @sophiecurio et al. focus on #NKG2D, which has anti-tumour functions. They show that signalling through this potent immunoreceptor can also promote cancer progression by modulating #IL17A-expressing #gdTcells https://t.co/zN6u98hHD4 5/10
Are NK cells or CD8 T cells better at killing tumors? Does it have to be one or the other?
1) Excited to share our group’s recent work, led by @BerengereSalome, demonstrating NKG2A+ CD8 T cells targeting HLA-I-neg. tumors like NK cells.
AddThis | Home https://t.co/P9NULI1tlz
For readers interested in cancer immunotherapy, this review in the August issue covers therapeutics being developed to stimulate natural killer (NK) cell responses, as well as NK cell adoptive transfer approaches https://t.co/nfe2W4qdB0
Fantastic talk @CChabannon discussing the solutions put forward by the scientific community at @TheEBMT_CTIWP towards a wider dissemination of CAR-T therapy in Europe.
Cell Therapy at the limits event https://t.co/qrSbEuYqFd
Congratulations @David_Tomaz for this PhD's achievement and coll. Ricardo Henriques, K. Gould and J. Dyson. Proud of our contribution to these studies demonstrating how the nanoscale organisation of NK cell receptors in the immune synapse impacts NKG2D-mediated NK cell killing.
🚨 Our paper together with @david_tomaz is out! "Nanoscale Colocalization of NK Cell Activating and Inhibitory Receptors Controls Signal Integration". With @MicrobeMatos, Nadia Guerra, Julian Dyson and Keith Gould. Check it out at: https://t.co/mz2zM8Nm4w
Nadia presented the latest work from the lab at the 19th meeting of the Society for Natural Immunity NK2022 in Fort Myers Florida. A great opportunity for a conceptual discussion around the paradoxical role played by NKG2D in Cancer Immunity!
Congratulations to Sophie and members of the Guerra and Coffelt labs for a remarkable study demonstrating how NKG2D signaling regulates IL-17A-producing γδT cells in mice to promote cancer progression https://t.co/SHoVC4v0VJ
There's still time to register for @Inst_Infection's online launch event, taking place Monday 4 - Tuesday 5 October!
Check out the programme and register here 👇https://t.co/zcOtzbMaR3